ATE110084T1 - Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung. - Google Patents
Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung.Info
- Publication number
- ATE110084T1 ATE110084T1 AT86906958T AT86906958T ATE110084T1 AT E110084 T1 ATE110084 T1 AT E110084T1 AT 86906958 T AT86906958 T AT 86906958T AT 86906958 T AT86906958 T AT 86906958T AT E110084 T1 ATE110084 T1 AT E110084T1
- Authority
- AT
- Austria
- Prior art keywords
- monoclonal antibody
- human monoclonal
- anticytomegaloviral
- production
- cmv
- Prior art date
Links
- 230000001512 anti-cytomegaloviral effect Effects 0.000 title 1
- 241000701022 Cytomegalovirus Species 0.000 abstract 1
- 102000003886 Glycoproteins Human genes 0.000 abstract 1
- 108090000288 Glycoproteins Proteins 0.000 abstract 1
- 206010035226 Plasma cell myeloma Diseases 0.000 abstract 1
- 239000000427 antigen Substances 0.000 abstract 1
- 230000000890 antigenic effect Effects 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 230000004927 fusion Effects 0.000 abstract 1
- 210000004408 hybridoma Anatomy 0.000 abstract 1
- 201000000050 myeloid neoplasm Diseases 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 210000004989 spleen cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
- C07K16/088—Varicella-zoster virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
- C07K16/089—Cytomegalovirus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP27350485 | 1985-12-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE110084T1 true ATE110084T1 (de) | 1994-09-15 |
Family
ID=17528811
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT86906958T ATE110084T1 (de) | 1985-12-06 | 1986-12-02 | Anticytomegaloviraler menschlicher monoklonaler antikörper und dessen herstellung. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5043281A (de) |
EP (1) | EP0248909B1 (de) |
KR (1) | KR910000736B1 (de) |
AT (1) | ATE110084T1 (de) |
AU (1) | AU590656B2 (de) |
DE (1) | DE3650032T2 (de) |
WO (1) | WO1987003602A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5153311A (en) * | 1986-11-24 | 1992-10-06 | The Children's Hospital, Incorporated | Immunogenic glycoproteins of human cytomegalovirus gCII |
US5126130A (en) * | 1986-11-24 | 1992-06-30 | The Childrens Hospital Incorporated | Monoclonal antibodies reactive with specific antigenic sites on human cytomegalovirus glycoprotein a |
US6511665B1 (en) * | 1987-11-25 | 2003-01-28 | Immunex Corporation | Antibodies to interleukin-1 receptors |
WO1989007143A1 (en) * | 1988-01-29 | 1989-08-10 | Chiron Corporation | Recombinant cmv neutralizing proteins |
SE9201281L (sv) * | 1992-04-23 | 1993-10-24 | Bioinvent Int Ab | Nya humana monoklonala antikroppar och förfarande för framställning därav |
GB9221654D0 (en) * | 1992-10-15 | 1992-11-25 | Scotgen Ltd | Recombinant human anti-cytomegalovirus antibodies |
US5750106A (en) * | 1993-01-28 | 1998-05-12 | Novartis Ag | Human monoclonal antibodies to cytomegalovirus |
AU3993695A (en) * | 1994-12-07 | 1996-06-26 | Fujisawa Pharmaceutical Co., Ltd. | Method of measuring the concentration of fk506-binding protein |
ES2187796T3 (es) | 1996-07-12 | 2003-06-16 | Organon Teknika Bv | Reactivo de peptidos que permiten la deteccion de citomegalovirus (cmv) humano. |
WO2007094423A1 (ja) * | 2006-02-15 | 2007-08-23 | Evec Incorporated | ヒトサイトメガロウイルスに結合するヒトのモノクローナル抗体並びにその抗原結合部分 |
GB0700133D0 (en) | 2007-01-04 | 2007-02-14 | Humabs Llc | Human cytomegalovirus neutralising antibodies and use thereof |
US7947274B2 (en) | 2007-01-04 | 2011-05-24 | Humabs, LLC. | Human cytomegalovirus neutralising antibodies and use thereof |
WO2009085383A1 (en) * | 2007-12-19 | 2009-07-09 | Dcb-Usa Llc | Anti-human cytomegalovirus antibodies |
NZ591055A (en) * | 2008-07-16 | 2012-08-31 | Inst Research In Biomedicine | Human cytomegalovirus neutralising antibodies and use thereof |
UA106354C2 (ru) | 2008-07-16 | 2014-08-26 | Инститьют Фо Рисерч Ин Байомедсин | Антитела, нейтрализующие цитомегаловирус человека, и их применение |
KR101390015B1 (ko) | 2009-04-01 | 2014-04-29 | 에베크 인코포레이티드 | 인간 사이토메갈로바이러스 gB 당단백질의 AD1 영역에 존재하는 특정한 불연속 에피토프에 결합하는 모노클로날 항체 및 그의 항원 결합성 단편 |
US20110033389A1 (en) * | 2009-04-29 | 2011-02-10 | Zhifeng Chen | Modified antibodies for passive immunotherapy |
BR112012015523A2 (pt) | 2009-12-23 | 2017-04-18 | 4-Antibody Ag | membros de ligação do citomegalovirus humano, composição contendo os mesmos, método de tratamento, moléculas de anticorpo, método de produção, molecular de ácido nucléico, célula hospedeira, e, método de neutralização do hcmv. |
JP7350716B2 (ja) * | 2018-03-27 | 2023-09-26 | 森永乳業株式会社 | 微生物の細胞及び/又はウイルスの測定方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4574116A (en) * | 1983-01-13 | 1986-03-04 | The Board Of Trustees Of The Leland Stanford Jr. University | Methods and cell lines for immortalization and monoclonal antibody production by antigen-stimulated B-lymphocytes |
FR2543570B1 (fr) * | 1983-03-31 | 1985-08-09 | Pasteur Institut | Anticorps monoclonaux anticytomegalovirus humains, hybridomes secreteurs de ces anticorps et polypeptides porteurs d'un determinant antigenique sequentiel de cytomegalovirus humains |
GB8404368D0 (en) * | 1984-02-20 | 1984-03-28 | Cogent Ltd | Monoclonal antibodies to human cytomegalovirus |
EP0198086B1 (de) * | 1984-09-28 | 1991-01-16 | Teijin Limited | Maus/mensch-hybridoma mit erzeugung von antiviralen menschlichen antikörpern, deren herstellung und antivirale menschliche monoklonale antikörper |
JP2933786B2 (ja) * | 1992-10-13 | 1999-08-16 | 甲南電機株式会社 | 逃がし弁 |
JPH06181782A (ja) * | 1992-12-21 | 1994-07-05 | Mitsubishi Petrochem Co Ltd | 酵素反応方法 |
-
1986
- 1986-12-02 KR KR1019870700674A patent/KR910000736B1/ko not_active IP Right Cessation
- 1986-12-02 AU AU67218/87A patent/AU590656B2/en not_active Expired
- 1986-12-02 AT AT86906958T patent/ATE110084T1/de not_active IP Right Cessation
- 1986-12-02 WO PCT/JP1986/000613 patent/WO1987003602A1/ja active IP Right Grant
- 1986-12-02 DE DE3650032T patent/DE3650032T2/de not_active Expired - Lifetime
- 1986-12-02 EP EP86906958A patent/EP0248909B1/de not_active Expired - Lifetime
-
1990
- 1990-09-27 US US07/590,446 patent/US5043281A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0248909A1 (de) | 1987-12-16 |
AU590656B2 (en) | 1989-11-09 |
EP0248909A4 (de) | 1989-11-07 |
DE3650032D1 (de) | 1994-09-22 |
EP0248909B1 (de) | 1994-08-17 |
KR880700823A (ko) | 1988-04-12 |
KR910000736B1 (ko) | 1991-02-06 |
WO1987003602A1 (en) | 1987-06-18 |
AU6721887A (en) | 1987-06-30 |
US5043281A (en) | 1991-08-27 |
DE3650032T2 (de) | 1995-03-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EELA | Cancelled due to lapse of time |