ES8401982A1 - "procedimiento de preparacion de globulina antilinfocitaria t". - Google Patents
"procedimiento de preparacion de globulina antilinfocitaria t".Info
- Publication number
- ES8401982A1 ES8401982A1 ES509504A ES509504A ES8401982A1 ES 8401982 A1 ES8401982 A1 ES 8401982A1 ES 509504 A ES509504 A ES 509504A ES 509504 A ES509504 A ES 509504A ES 8401982 A1 ES8401982 A1 ES 8401982A1
- Authority
- ES
- Spain
- Prior art keywords
- lymphocyte globulin
- cells
- preparation
- lymphocytes
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
- Y10S530/809—Fused cells, e.g. hybridoma
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/829—Blood
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
- Y10S530/851—Placenta; amniotic fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
PROCEDIMIENTO DE PREPARACION DE GLOBULINA ANTILINFOCITARIA T.COMPRENDE LAS SIGUIENTES ETAPAS: 1) CENTRIFUGADO DE LAS CELULAS DE LINFOBLASTOS T; 2) FIJACION DE LA SUSPENSION CELULAR, CON UN MEDIO CELULAR FISIOLOGICO (CL 15), A UNA CONCENTRACION CELULAR DE, POR EJEMPLO, 30 D 10 CELULAS POR ML; 3) INMUNIZACION DE LOS CONEJOS MEDIANTE LA APLICACION INTRAVENOSA DE 3 ML DE SUSPENSION CELULAR EN LA VENA AURICULAR Y DEGRADACION DE LOS ANIMALES DESPUES DE UN PERIODO DE INMUNIZACION DE 4 SEMANAS; 4) OBTENCION DEL SUERO POR CENTRIFUGADO DE LA SANGRE; 5) DETERMINACIONDE LA TITULACION DE LOS ANTICUERPOS Y DE LAS PRUEBAS DE ESTERILIDAD Y POSTERIOR MEZCLA DEL SUERO; 6) ABSORCION DEL SUERO CON DISTINTAS CELULAS HUMANAS; 7) DEPURACION DEL ANTISUERO Y SU FRACCIONAMIENTO PARA LA OBTENCION DE LA FRACCION GLOBULINICA; 8) AJUSTE DE LA FRACCION INMUNOGLOBULINA A UNA CONCENTRACION DE ALBUMINA DE 20 MG/ML; 9) ULTRACENTRIFUGACION Y ESTERILIZACION FINALMENTE DE LA GLOBULINA ANTILINFOCITARIA T.EFECTO INHIBIDOR DEL RECHACE DE ORGANOS TRANSPLANTADOS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813105150 DE3105150A1 (de) | 1981-02-12 | 1981-02-12 | Herstellung von anti-t-lymphozyten-globulin. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8401982A1 true ES8401982A1 (es) | 1984-01-16 |
ES509504A0 ES509504A0 (es) | 1984-01-16 |
Family
ID=6124731
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES509504A Granted ES509504A0 (es) | 1981-02-12 | 1982-02-11 | "procedimiento de preparacion de globulina antilinfocitaria t". |
Country Status (19)
Country | Link |
---|---|
US (1) | US4541953A (es) |
AT (1) | AT377698B (es) |
AU (1) | AU550257B2 (es) |
BE (1) | BE891944A (es) |
CA (1) | CA1184491A (es) |
CH (1) | CH652410A5 (es) |
DE (1) | DE3105150A1 (es) |
DK (1) | DK56882A (es) |
ES (1) | ES509504A0 (es) |
FI (1) | FI72139C (es) |
FR (1) | FR2499413B1 (es) |
GB (1) | GB2093037B (es) |
HU (1) | HU189998B (es) |
IT (1) | IT1195296B (es) |
LU (1) | LU83932A1 (es) |
NL (1) | NL8200458A (es) |
NO (1) | NO157422C (es) |
SE (1) | SE460826B (es) |
ZA (1) | ZA82905B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3483996D1 (de) * | 1983-09-15 | 1991-02-28 | Univ Leland Stanford Junior | Allotransplantat mit verminderter immunogenitaet und verfahren und reagenz fuer seine herstellung. |
US4681760A (en) * | 1985-04-17 | 1987-07-21 | The Board Of Trustees Of The Leland Stanford Junior University | Method of conferring immunotolerance to a specific antigen |
US5011684A (en) * | 1985-09-05 | 1991-04-30 | Beth Israel Hospital Association | Lysing or blocking unwanted cells with IL-2 receptor-specific binding substance |
US5785966A (en) * | 1994-06-15 | 1998-07-28 | Coles; John G. | Inhibition of human xenogenic or allogenic antibodies to reduce xenograft or allograft rejection in human recipients |
FR2878852B1 (fr) * | 2000-09-28 | 2007-02-23 | Imtix Sangstat | Procede de production d'immunoglobulines anti-thymocytes humains |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4363799A (en) * | 1979-03-20 | 1982-12-14 | Ortho Pharmaceutical Corporation | Monoclonal antibody to human T cells, and methods for preparing same |
US4361549A (en) * | 1979-04-26 | 1982-11-30 | Ortho Pharmaceutical Corporation | Complement-fixing monoclonal antibody to human T cells, and methods of preparing same |
US4364933A (en) * | 1979-12-04 | 1982-12-21 | Ortho Pharmaceutical Corporation | Monoclonal antibody to a human thymocyte antigen and methods of preparing same |
US4364935A (en) * | 1979-12-04 | 1982-12-21 | Ortho Pharmaceutical Corporation | Monoclonal antibody to a human prothymocyte antigen and methods of preparing same |
US4361550A (en) * | 1979-12-04 | 1982-11-30 | Ortho Pharmaceutical Corporation | Complement-fixing monoclonal antibody to human suppressor T cells and methods of preparing same |
-
1981
- 1981-02-12 DE DE19813105150 patent/DE3105150A1/de active Granted
- 1981-11-23 GB GB8135192A patent/GB2093037B/en not_active Expired
- 1981-11-24 IT IT25247/81A patent/IT1195296B/it active
- 1981-12-11 FR FR8123180A patent/FR2499413B1/fr not_active Expired
-
1982
- 1982-01-05 NO NO820014A patent/NO157422C/no unknown
- 1982-01-14 AT AT0011482A patent/AT377698B/de not_active IP Right Cessation
- 1982-01-26 FI FI820233A patent/FI72139C/fi not_active IP Right Cessation
- 1982-01-29 BE BE0/207174A patent/BE891944A/fr not_active IP Right Cessation
- 1982-02-04 SE SE8200639A patent/SE460826B/sv not_active IP Right Cessation
- 1982-02-05 NL NL8200458A patent/NL8200458A/nl not_active Application Discontinuation
- 1982-02-08 CA CA000395714A patent/CA1184491A/en not_active Expired
- 1982-02-10 DK DK56882A patent/DK56882A/da not_active Application Discontinuation
- 1982-02-10 LU LU83932A patent/LU83932A1/de unknown
- 1982-02-11 HU HU82426A patent/HU189998B/hu not_active IP Right Cessation
- 1982-02-11 ES ES509504A patent/ES509504A0/es active Granted
- 1982-02-11 AU AU80373/82A patent/AU550257B2/en not_active Ceased
- 1982-02-12 CH CH905/82A patent/CH652410A5/de not_active IP Right Cessation
- 1982-02-12 ZA ZA82905A patent/ZA82905B/xx unknown
-
1984
- 1984-02-21 US US06/582,030 patent/US4541953A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATA11482A (de) | 1984-09-15 |
CA1184491A (en) | 1985-03-26 |
NO157422B (no) | 1987-12-07 |
BE891944A (fr) | 1982-05-17 |
GB2093037A (en) | 1982-08-25 |
DK56882A (da) | 1982-08-13 |
IT1195296B (it) | 1988-10-12 |
US4541953A (en) | 1985-09-17 |
FI72139C (fi) | 1987-04-13 |
SE460826B (sv) | 1989-11-27 |
DE3105150A1 (de) | 1982-08-19 |
ES509504A0 (es) | 1984-01-16 |
NO157422C (no) | 1988-03-16 |
AT377698B (de) | 1985-04-25 |
FR2499413A1 (fr) | 1982-08-13 |
FI72139B (fi) | 1986-12-31 |
IT8125247A0 (it) | 1981-11-24 |
SE8200639L (sv) | 1982-08-13 |
AU8037382A (en) | 1982-08-19 |
FR2499413B1 (fr) | 1985-08-30 |
FI820233L (fi) | 1982-08-13 |
CH652410A5 (de) | 1985-11-15 |
NO820014L (no) | 1982-08-13 |
NL8200458A (nl) | 1982-09-01 |
DE3105150C2 (es) | 1989-02-23 |
GB2093037B (en) | 1984-07-18 |
LU83932A1 (de) | 1982-07-07 |
HU189998B (en) | 1986-08-28 |
ZA82905B (en) | 1982-12-29 |
AU550257B2 (en) | 1986-03-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20001009 |