ES8505409A1 - Procedimiento para purificar interferon de humano - Google Patents

Procedimiento para purificar interferon de humano

Info

Publication number
ES8505409A1
ES8505409A1 ES535509A ES535509A ES8505409A1 ES 8505409 A1 ES8505409 A1 ES 8505409A1 ES 535509 A ES535509 A ES 535509A ES 535509 A ES535509 A ES 535509A ES 8505409 A1 ES8505409 A1 ES 8505409A1
Authority
ES
Spain
Prior art keywords
cell lines
hybrid cell
preparing
cells
immunoglobin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES535509A
Other languages
English (en)
Other versions
ES535509A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of ES535509A0 publication Critical patent/ES535509A0/es
Publication of ES8505409A1 publication Critical patent/ES8505409A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

METODO DE PURIFICACION DE INTERFERON DE HUMANO.CONSISTE EN PURIFICAR INTERFERON DE HUMANO DEL TIPO BAB MEDIANTE CROMATOGRAFIA A TRAVES DE UNA COLUMNA DE AFINIDAD DE ANTICUERPO DE IGC, FIJADO COVALENTEMENTE A UN SOPORTE, TAL COMO SEPHAROSE ACTIVADO; SEGUIDO DE LA PURIFICACION A TRAVES DE UN INTERCAMBIADOR DE CATIONES ACIDO.
ES535509A 1983-02-22 1984-08-30 Procedimiento para purificar interferon de humano Expired ES8505409A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19833306060 DE3306060A1 (de) 1983-02-22 1983-02-22 Neue immunglobulin-produzierende hybridzellinien, deren verwendung und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
ES535509A0 ES535509A0 (es) 1985-05-16
ES8505409A1 true ES8505409A1 (es) 1985-05-16

Family

ID=6191474

Family Applications (2)

Application Number Title Priority Date Filing Date
ES529912A Expired ES8503371A1 (es) 1983-02-22 1984-02-21 Procedimiento para preparar nuevos anticuerpos de igg de raton con especificidad anti-interferon de humano
ES535509A Expired ES8505409A1 (es) 1983-02-22 1984-08-30 Procedimiento para purificar interferon de humano

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES529912A Expired ES8503371A1 (es) 1983-02-22 1984-02-21 Procedimiento para preparar nuevos anticuerpos de igg de raton con especificidad anti-interferon de humano

Country Status (7)

Country Link
EP (1) EP0119476A3 (es)
JP (1) JPS59224687A (es)
DE (1) DE3306060A1 (es)
DK (1) DK85084A (es)
ES (2) ES8503371A1 (es)
FI (1) FI840675A (es)
IL (1) IL71017A (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
AU6032786A (en) * 1985-07-25 1987-01-29 University Of Minnesota Detection, imaging and therapy of renal cell carcinoma with monoclonal antibodies in vivo
GB8615353D0 (en) * 1986-06-24 1986-07-30 Antibioticos Sa Interferon
DE3633323A1 (de) * 1986-10-01 1988-04-07 Boehringer Ingelheim Int Neue monoklonale antikoerper gegen ifn-omega, verfahren zu ihrer herstellung und deren verwendung zur reinigung sowie zum nachweis von ifn-omega
SE468251B (sv) 1989-06-20 1992-11-30 Bionative Ab Reningsprocess foer interferon
ATE104348T1 (de) * 1990-07-10 1994-04-15 Boehringer Ingelheim Int O-glycosyliertes ifn-alpha.
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
US20100143372A1 (en) 2006-12-06 2010-06-10 Medimmune, Llc Interferon alpha-induced pharmacodynamic markers
AU2008247398B2 (en) 2007-05-03 2013-10-10 Medimmune, Llc Interferon alpha-induced pharmacodynamic markers
AU2008324800B2 (en) 2007-11-05 2014-03-27 Astrazeneca Ab Methods of treating scleroderma
US20110262928A1 (en) 2008-02-08 2011-10-27 Medimmune Llc Disease markers and uses thereof
AU2010289383B2 (en) 2009-09-03 2015-04-16 Medimmune, Llc Type 1 interferon diagnostic
CA3128785A1 (en) 2019-02-15 2020-08-20 Astrazeneca Ab Type i interferon-mediated disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI77877C (fi) * 1979-04-20 1989-05-10 Technobiotic Ltd Foerfarande foer framstaellning och rening av human le-formig interferonprotein.
JPH0611235B2 (ja) * 1980-04-11 1994-02-16 セルテック・リミテッド モノクロ−ナル抗体
AU561649B2 (en) * 1981-02-27 1987-05-14 F. Hoffmann-La Roche Ag Antibodies to proteins
WO1984003106A1 (en) * 1983-02-04 1984-08-16 Wadley Inst Of Molecular Medic Production and characterization of hybridoma antibodies directed specifically against common determinant(s) present among closely related, but distinct proteins
GB8303165D0 (en) * 1983-02-04 1983-03-09 Secher D S Monoclonal antibody

Also Published As

Publication number Publication date
FI840675A0 (fi) 1984-02-20
ES535509A0 (es) 1985-05-16
EP0119476A3 (de) 1987-04-08
DK85084A (da) 1984-08-23
ES529912A0 (es) 1985-02-16
FI840675A (fi) 1984-08-23
JPS59224687A (ja) 1984-12-17
IL71017A0 (en) 1984-05-31
EP0119476A2 (de) 1984-09-26
DE3306060A1 (de) 1984-08-23
DK85084D0 (da) 1984-02-21
IL71017A (en) 1987-12-31
ES8503371A1 (es) 1985-02-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990301