NO167533C - Fremgangsmaate ved fremstilling av faktor viii koagulerende polypeptider og monoklonale antistoffer overfor disse. - Google Patents

Fremgangsmaate ved fremstilling av faktor viii koagulerende polypeptider og monoklonale antistoffer overfor disse.

Info

Publication number
NO167533C
NO167533C NO841277A NO841277A NO167533C NO 167533 C NO167533 C NO 167533C NO 841277 A NO841277 A NO 841277A NO 841277 A NO841277 A NO 841277A NO 167533 C NO167533 C NO 167533C
Authority
NO
Norway
Prior art keywords
polypeptides
reacts
factor viii
those
react
Prior art date
Application number
NO841277A
Other languages
English (en)
Other versions
NO167533B (no
NO841277L (no
Inventor
Theodore S Zimmermann
Carol A Fulcher
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27046849&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO167533(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of NO841277L publication Critical patent/NO841277L/no
Publication of NO167533B publication Critical patent/NO167533B/no
Publication of NO167533C publication Critical patent/NO167533C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745Blood coagulation or fibrinolysis factors
    • C07K14/755Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO841277A 1983-03-31 1984-03-30 Fremgangsmaate ved fremstilling av faktor viii koagulerende polypeptider og monoklonale antistoffer overfor disse. NO167533C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US48110583A 1983-03-31 1983-03-31
US55650883A 1983-11-30 1983-11-30

Publications (3)

Publication Number Publication Date
NO841277L NO841277L (no) 1984-10-01
NO167533B NO167533B (no) 1991-08-05
NO167533C true NO167533C (no) 1991-11-13

Family

ID=27046849

Family Applications (1)

Application Number Title Priority Date Filing Date
NO841277A NO167533C (no) 1983-03-31 1984-03-30 Fremgangsmaate ved fremstilling av faktor viii koagulerende polypeptider og monoklonale antistoffer overfor disse.

Country Status (12)

Country Link
EP (3) EP0123945B2 (no)
JP (2) JPH0829089B2 (no)
AT (2) ATE135400T1 (no)
AU (1) AU572128B2 (no)
CA (1) CA1341506C (no)
DE (2) DE3486453T2 (no)
DK (2) DK172036B1 (no)
FI (1) FI841281A (no)
IE (2) IE80858B1 (no)
NO (1) NO167533C (no)
SG (2) SG49675A1 (no)
ZA (1) ZA842418B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4657894A (en) * 1983-03-31 1987-04-14 Scripps Clinic & Research Foundation New factor VIII coagulant polypeptides
DE152746T1 (de) * 1984-01-12 1986-04-10 Chiron Corp., Emeryville, Calif. Monoklonale antikoerper gegen faktor-viii-c.
DK165506C (da) * 1984-01-12 1993-04-19 Chiron Corp Proteinpraeparat med koagulationsaktivitet samt fremgangsmaade til fremstilling deraf
US5045455A (en) * 1984-01-12 1991-09-03 Chiron Corporation Factor VIII:C cDNA cloning and expression
US4716117A (en) * 1984-10-26 1987-12-29 Chiron Corporation Monoclonal antibodies to factor VIIIC
US7138505B1 (en) 1984-01-12 2006-11-21 Novartis Vaccines And Diagnostics, Inc. Factor VIII:C nucleic acid molecules
US5004804A (en) * 1984-01-12 1991-04-02 Nordisk Gentofte Method and composition for preparation of factor VIIIC
US4965199A (en) * 1984-04-20 1990-10-23 Genentech, Inc. Preparation of functional human factor VIII in mammalian cells using methotrexate based selection
IL74909A (en) * 1984-04-20 1992-01-15 Genentech Inc Preparation of functional human factor viii and dna sequences,expression vectors,transformed microorganisms and cell lines used therein
SE8501050D0 (sv) * 1985-03-05 1985-03-05 Kabivitrum Ab Biologically active fragments of human antihemophilic factor and method for preparation thereof
KR910006424B1 (ko) * 1985-08-21 1991-08-24 인코텍스 비.브이 편성브리프(brief) 제조방법
WO1988000210A1 (en) * 1986-06-24 1988-01-14 Nordisk Gentofte A/S A process for producing a coagulation active complex of factor viii fragments
CA1339946C (en) * 1987-03-31 1998-07-07 Michael J. Griffith Ultrapurification process for polypeptides
EP0690126B1 (en) 1987-06-12 2001-11-28 Baxter Aktiengesellschaft Novel proteins with factor VIII activitiy: process for their preparation using genetically-engineered cells and pharmaceutical compositions containing them
IL88309A0 (en) * 1987-11-17 1989-06-30 Scripps Clinic Res Peptides for use in the purification of factor viii
FR2662166A1 (fr) * 1990-05-18 1991-11-22 Fondation Nale Transfusion San Procede de preparation de facteur viii de tres haute purete comprenant une etape rapide d'immunoadsorption.
WO1995003332A1 (en) * 1993-07-23 1995-02-02 Baxter International Inc. Activated human factor viii and method of preparation
US5576291A (en) * 1993-09-13 1996-11-19 Baxter International Inc. Activated factor VIII as a therapeutic agent and method of treating factor VIII deficiency
CN100553678C (zh) 1999-02-22 2009-10-28 巴克斯特国际有限公司 新的无白蛋白的因子ⅷ制剂
EP1418810A4 (en) 2001-08-03 2006-08-02 Us Gov Health & Human Serv TREATMENT OF HEMOPHILIA ORAL
ES2706296T3 (es) 2008-11-07 2019-03-28 Univ Connecticut Formulaciones de Factor VIII
BRPI1105317A2 (pt) 2011-01-24 2013-04-30 Fundacco Hemoct De Ribeirco Preto produÇço estÁvel e em larga escala de fviii humano em linhagem celular humana sk-hep-1

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364937A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human T cell antigen and methods of preparing same
US4364936A (en) * 1980-01-08 1982-12-21 Ortho Pharmaceutical Corporation Monoclonal antibody to a human monocyte antigen and methods of preparing same
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4397841A (en) * 1982-06-28 1983-08-09 Monsanto Company Production of blood coagulation factor VIII:C

Also Published As

Publication number Publication date
IE80858B1 (en) 1999-04-21
JPS59184130A (ja) 1984-10-19
DK50497A (da) 1997-05-02
AU572128B2 (en) 1988-05-05
ZA842418B (en) 1984-11-28
IE960783L (en) 1984-09-30
DE3486423T2 (de) 1996-09-19
EP0123945A1 (en) 1984-11-07
DE3486453T2 (de) 1998-02-26
DK172036B1 (da) 1997-09-22
ATE135400T1 (de) 1996-03-15
JPH0638790A (ja) 1994-02-15
JPH0829089B2 (ja) 1996-03-27
NO167533B (no) 1991-08-05
DE3486453D1 (de) 1997-08-21
EP0770396A2 (en) 1997-05-02
DK174984A (da) 1984-10-01
DE3486423T3 (de) 2001-02-08
SG49675A1 (en) 1998-06-15
CA1341506C (en) 2006-06-06
DE3486423D1 (de) 1996-04-18
ATE155490T1 (de) 1997-08-15
IE80638B1 (en) 1998-10-21
FI841281A (fi) 1984-10-01
IE840788L (en) 1984-09-30
EP0561427A1 (en) 1993-09-22
EP0561427B1 (en) 1997-07-16
AU2627284A (en) 1984-10-04
DK174984D0 (da) 1984-03-30
NO841277L (no) 1984-10-01
EP0770396A3 (en) 1997-07-23
EP0123945B2 (en) 2000-04-19
FI841281A0 (fi) 1984-03-30
EP0123945B1 (en) 1996-03-13
SG48229A1 (en) 1998-04-17

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