DE3854904T2 - Peptide, die von der Faktor VIII-Bindungsdomäne des von Willebrand-Faktors abgeleitet sind - Google Patents
Peptide, die von der Faktor VIII-Bindungsdomäne des von Willebrand-Faktors abgeleitet sindInfo
- Publication number
- DE3854904T2 DE3854904T2 DE3854904T DE3854904T DE3854904T2 DE 3854904 T2 DE3854904 T2 DE 3854904T2 DE 3854904 T DE3854904 T DE 3854904T DE 3854904 T DE3854904 T DE 3854904T DE 3854904 T2 DE3854904 T2 DE 3854904T2
- Authority
- DE
- Germany
- Prior art keywords
- factor
- von willebrand
- binding domain
- factor viii
- peptides derived
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07045032 US5043429B1 (en) | 1987-05-01 | 1987-05-01 | Protein fragments containing factor VIII binding domain of von willebrand factor |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3854904D1 DE3854904D1 (de) | 1996-02-29 |
DE3854904T2 true DE3854904T2 (de) | 1996-07-04 |
Family
ID=21935641
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE3854904T Expired - Lifetime DE3854904T2 (de) | 1987-05-01 | 1988-04-27 | Peptide, die von der Faktor VIII-Bindungsdomäne des von Willebrand-Faktors abgeleitet sind |
Country Status (9)
Country | Link |
---|---|
US (3) | US5043429B1 (de) |
EP (1) | EP0294025B1 (de) |
JP (1) | JP2631127B2 (de) |
AT (1) | ATE133183T1 (de) |
AU (1) | AU626255B2 (de) |
CA (1) | CA1341097C (de) |
DE (1) | DE3854904T2 (de) |
ES (1) | ES2081804T3 (de) |
GR (1) | GR3018870T3 (de) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5043429B1 (en) * | 1987-05-01 | 1997-10-14 | Scripps Research Inst | Protein fragments containing factor VIII binding domain of von willebrand factor |
FR2632309B1 (fr) * | 1988-06-07 | 1990-08-24 | Lille Transfusion Sanguine | Procede de purification par voie chromatographique de proteines, notamment de facteur viii, et les produits obtenus |
US5849536A (en) * | 1990-03-02 | 1998-12-15 | Bio-Technology General Corp. | Cloning and production of human von willebrand factor GPIb binding domain polypeptides and methods of using same |
US6008193A (en) * | 1990-03-02 | 1999-12-28 | Bio-Technology General Corp. | Methods of using human von Willebrand factor GPIb binding domain polypeptides |
US5530100A (en) * | 1990-05-07 | 1996-06-25 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Methods for purification of recombinantly produced proteins |
US5629287A (en) * | 1991-01-18 | 1997-05-13 | University College London | Depot formulations |
US5610148A (en) * | 1991-01-18 | 1997-03-11 | University College London | Macroscopically oriented cell adhesion protein for wound treatment |
ES2233924T3 (es) * | 1991-06-20 | 2005-06-16 | Aventis Behring L.L.C. | Un procedimiento para preparar fragmentos terapeuticos de factor von willebrand. |
US5847086A (en) * | 1991-06-20 | 1998-12-08 | Centeon L.L.C. | Therapeutic fragments of von Willebrand factor |
AU3972793A (en) * | 1992-04-10 | 1993-11-18 | General Hospital Corporation, The | Cartilage matrix protein and methods for use |
US6005077A (en) * | 1995-11-10 | 1999-12-21 | Immuno Aktiengesellschaft | Use of von willebrand factor and pharmaceutical formulation |
DE19740310A1 (de) * | 1997-09-13 | 1999-04-01 | Octapharma Ag | Peptid mit Affinität zu Gerinnungsfaktor VIII |
KR100398058B1 (ko) * | 2001-05-18 | 2003-09-19 | 주식회사 경동도시가스 | 수식된 θ-알루미나에 담지되어 이루어진 니켈계 개질촉매및 이를 이용한 천연가스로부터 합성가스의 제조방법 |
US7566701B2 (en) * | 2004-09-07 | 2009-07-28 | Archemix Corp. | Aptamers to von Willebrand Factor and their use as thrombotic disease therapeutics |
AU2005282380A1 (en) * | 2004-09-07 | 2006-03-16 | Archemix Corp. | Aptamer medicinal chemistry |
EP1789096A4 (de) * | 2004-09-07 | 2009-07-08 | Archemix Corp | Aptamere für den von-willebrand-faktor und ihre verwendung als therapeutika für thrombotische erkrankungen |
WO2008150495A2 (en) * | 2007-06-01 | 2008-12-11 | Archemix Corp. | Vwf aptamer formulations and methods for use |
NZ600278A (en) | 2009-11-13 | 2014-04-30 | Grifols Therapeutics Inc | Von willebrand factor (vwf)-containing preparations, and methods, kits, and uses related thereto |
SG191186A1 (en) | 2010-12-15 | 2013-07-31 | Baxter Int | Eluate collection using conductivity gradient |
AU2012340501A1 (en) | 2011-12-19 | 2013-07-11 | Grifols, S.A. | Compositions, methods, and kits for preparing sialylated recombinant proteins |
NL2013007B1 (en) | 2014-06-16 | 2016-07-05 | Ablynx Nv | Methods of treating TTP with immunoglobulin single variable domains and uses thereof. |
KR102175878B1 (ko) | 2016-06-24 | 2020-11-06 | 재단법인 목암생명과학연구소 | Fviii 및 vwf 인자를 포함하는 키메라 단백질 및 그 용도 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4361509A (en) * | 1981-12-14 | 1982-11-30 | Scripps Clinic And Research Foundation | Ultrapurification of factor VIII using monoclonal antibodies |
US4661471A (en) * | 1984-04-10 | 1987-04-28 | New England Deaconess Hospital | Method of inhibiting and inducing human platelet aggregation |
US4683291A (en) * | 1985-10-28 | 1987-07-28 | Scripps Clinic And Research Foundation | Platelet binding inhibitors |
US5198349A (en) * | 1986-01-03 | 1993-03-30 | Genetics Institute, Inc. | Method for producing factor VIII:C and analogs |
WO1987004187A1 (en) * | 1986-01-03 | 1987-07-16 | Genetics Institute, Inc. | METHOD FOR PRODUCING FACTOR VIII:c-TYPE PROTEINS |
US5043429B1 (en) * | 1987-05-01 | 1997-10-14 | Scripps Research Inst | Protein fragments containing factor VIII binding domain of von willebrand factor |
-
1987
- 1987-05-01 US US07045032 patent/US5043429B1/en not_active Expired - Lifetime
-
1988
- 1988-04-26 CA CA000565057A patent/CA1341097C/en not_active Expired - Fee Related
- 1988-04-27 ES ES88303796T patent/ES2081804T3/es not_active Expired - Lifetime
- 1988-04-27 AT AT88303796T patent/ATE133183T1/de not_active IP Right Cessation
- 1988-04-27 EP EP88303796A patent/EP0294025B1/de not_active Expired - Lifetime
- 1988-04-27 DE DE3854904T patent/DE3854904T2/de not_active Expired - Lifetime
- 1988-04-28 AU AU15271/88A patent/AU626255B2/en not_active Expired
- 1988-05-02 JP JP63109854A patent/JP2631127B2/ja not_active Expired - Lifetime
-
1991
- 1991-07-03 US US07725560 patent/US5260274B1/en not_active Expired - Lifetime
-
1995
- 1995-03-24 US US08/410,574 patent/US5597711A/en not_active Expired - Lifetime
-
1996
- 1996-02-01 GR GR960400264T patent/GR3018870T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
ES2081804T3 (es) | 1996-03-16 |
DE3854904D1 (de) | 1996-02-29 |
JP2631127B2 (ja) | 1997-07-16 |
ATE133183T1 (de) | 1996-02-15 |
AU1527188A (en) | 1988-11-03 |
AU626255B2 (en) | 1992-07-30 |
JPS6456697A (en) | 1989-03-03 |
GR3018870T3 (en) | 1996-05-31 |
US5260274B1 (en) | 1998-01-20 |
US5043429A (en) | 1991-08-27 |
US5260274A (en) | 1993-11-09 |
EP0294025A2 (de) | 1988-12-07 |
US5597711A (en) | 1997-01-28 |
CA1341097C (en) | 2000-09-12 |
US5043429B1 (en) | 1997-10-14 |
EP0294025B1 (de) | 1996-01-17 |
EP0294025A3 (en) | 1989-11-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: THE SCRIPPS RESEARCH INSTITUTE, LA JOLLA, CALIF., |
|
8364 | No opposition during term of opposition |