DE3434104A1 - Wasserunloesliche zubereitung von hyaluronsaeure und verfahren dazu - Google Patents

Wasserunloesliche zubereitung von hyaluronsaeure und verfahren dazu

Info

Publication number
DE3434104A1
DE3434104A1 DE19843434104 DE3434104A DE3434104A1 DE 3434104 A1 DE3434104 A1 DE 3434104A1 DE 19843434104 DE19843434104 DE 19843434104 DE 3434104 A DE3434104 A DE 3434104A DE 3434104 A1 DE3434104 A1 DE 3434104A1
Authority
DE
Germany
Prior art keywords
hyaluronic acid
water
insoluble
minutes
film
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19843434104
Other languages
German (de)
English (en)
Other versions
DE3434104C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html
Inventor
Endre A. Riverdale N.Y. Balazs
Adolf Brooklyn N.Y. Leshchiner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Biosurgery Inc
Original Assignee
Biomatrix Inc Ridgefield NJ
Biomatrix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomatrix Inc Ridgefield NJ, Biomatrix Inc filed Critical Biomatrix Inc Ridgefield NJ
Publication of DE3434104A1 publication Critical patent/DE3434104A1/de
Application granted granted Critical
Publication of DE3434104C2 publication Critical patent/DE3434104C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Materials For Medical Uses (AREA)
DE19843434104 1983-12-15 1984-09-17 Wasserunloesliche zubereitung von hyaluronsaeure und verfahren dazu Granted DE3434104A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56181883A 1983-12-15 1983-12-15
US59807184A 1984-04-09 1984-04-09

Publications (2)

Publication Number Publication Date
DE3434104A1 true DE3434104A1 (de) 1985-08-29
DE3434104C2 DE3434104C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-06-20

Family

ID=27072762

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19843434104 Granted DE3434104A1 (de) 1983-12-15 1984-09-17 Wasserunloesliche zubereitung von hyaluronsaeure und verfahren dazu

Country Status (6)

Country Link
AU (1) AU551628B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1238043A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3434104A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FR (1) FR2556728B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2151244B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IT (1) IT1178588B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3520008A1 (de) * 1984-12-06 1986-06-19 Biomatrix Inc Hyaluronsaeure-gele und -mischgele sowie verfahren zu deren herstellung
DE3607897A1 (de) * 1985-03-12 1986-09-18 Biomatrix Inc., Ridgefield, N.J. Verfahren zur herstellung einer chemisch modifizierten hyaluronsaeurezubereitung

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5202431A (en) * 1985-07-08 1993-04-13 Fidia, S.P.A. Partial esters of hyaluronic acid
US4851521A (en) * 1985-07-08 1989-07-25 Fidia, S.P.A. Esters of hyaluronic acid
IT1198449B (it) * 1986-10-13 1988-12-21 F I D I Farmaceutici Italiani Esteri di alcoli polivalenti di acido ialuronico
US4937270A (en) * 1987-09-18 1990-06-26 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
US6174999B1 (en) 1987-09-18 2001-01-16 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US6610669B1 (en) 1987-09-18 2003-08-26 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5527893A (en) * 1987-09-18 1996-06-18 Genzyme Corporation Water insoluble derivatives of polyanionic polysaccharides
US5017229A (en) * 1990-06-25 1991-05-21 Genzyme Corporation Water insoluble derivatives of hyaluronic acid
AU619760B2 (en) * 1987-12-10 1992-02-06 Genzyme Biosurgery Corporation Hylan preparation and method of recovery thereof from animal tissues
US4888016A (en) * 1988-02-10 1989-12-19 Langerman David W "Spare parts" for use in ophthalmic surgical procedures
JP2975105B2 (ja) * 1988-12-29 1999-11-10 アン・ルイス・チヤング ダイヤフラムポンプ
IT1260154B (it) * 1992-07-03 1996-03-28 Lanfranco Callegaro Acido ialuronico e suoi derivati in polimeri interpenetranti (ipn)
US5550112A (en) * 1992-12-30 1996-08-27 Patent Biopharmaceutics, Inc. Hyaluronic acid-urea pharmaceutical compositions and uses
US5679655A (en) * 1993-08-04 1997-10-21 Patent Biopharmaceutics, Inc. Method of treating lesions resulting from genital herpes with hyaluronic acid-urea pharmaceutical compositions
US5531716A (en) * 1993-09-29 1996-07-02 Hercules Incorporated Medical devices subject to triggered disintegration
US6294202B1 (en) 1994-10-06 2001-09-25 Genzyme Corporation Compositions containing polyanionic polysaccharides and hydrophobic bioabsorbable polymers
ES2248817T3 (es) * 1995-06-06 2006-03-16 C.R. Bard, Inc. Procedimiento de preparacion de particulas reticuladas de polimeros hidrosolubles, las particulas obtenidas y su utilizacion.
US6214331B1 (en) 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6060534A (en) 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
US6368356B1 (en) 1996-07-11 2002-04-09 Scimed Life Systems, Inc. Medical devices comprising hydrogel polymers having improved mechanical properties
DE69822285T2 (de) * 1998-02-27 2005-01-27 Stichting Hyppomedics Verfahren zur Herstellung von vernetzter Hyaluronsäure
GB9902652D0 (en) * 1999-02-05 1999-03-31 Fermentech Med Ltd Process
US6521223B1 (en) * 2000-02-14 2003-02-18 Genzyme Corporation Single phase gels for the prevention of adhesions
US20050222081A1 (en) * 2002-04-17 2005-10-06 Gianolio Diego A Cross-linked hyaluronate compounds
AU2003234140A1 (en) 2002-04-17 2003-11-03 Genzyme Corporation Aziridine compounds and their use in medical devices
AU2003901834A0 (en) * 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions
US8313765B2 (en) 2003-12-04 2012-11-20 Industrial Technology Research Institute Biodegradable hyaluronic acid derivative, biodegradable polymeric micelle composition and pharmaceutical or bioactive composition
GB2408741B (en) 2003-12-04 2008-06-18 Ind Tech Res Inst Hyaluronic acid derivative with urethane linkage
US20050220721A1 (en) 2004-03-17 2005-10-06 Kablik J J Anti-adhesion spraying
US7858107B2 (en) 2004-09-10 2010-12-28 Medtronic Xomed, Inc. Flexible bioresorbable hemostatic packing and stent having a preselectable in-vivo residence time
FR2882366B1 (fr) 2005-02-18 2008-04-18 Coletica Sa Polymere reticule de carbohydrate, notamment a base de polysaccharides et/ou de polyols
GB2423252B (en) * 2005-02-18 2007-10-17 Engelhard Lyon Cross-linked polymer of carbohydrate, notably based on polysaccharides, and/or on oligosaccharides and/or on polyols
WO2007015579A1 (ja) 2005-08-04 2007-02-08 Teijin Limited セルロース誘導体
FR2918377B1 (fr) 2007-07-05 2010-10-08 Estelle Piron Gel co-reticule de polysaccharides
KR100990301B1 (ko) 2007-09-28 2010-10-26 가부시키가이샤 시세이도 팽윤성 가교 히알루론산 분말과 그 제조 방법
FR2924615B1 (fr) 2007-12-07 2010-01-22 Vivacy Lab Hydrogel cohesif biodegradable.
US10266684B2 (en) 2012-03-12 2019-04-23 Colorado State University Research Foundation Glycosaminoglycan and synthetic polymer materials for blood-contacting applications
NZ629494A (en) 2012-03-12 2017-02-24 Univ Colorado State Res Found Glycosaminoglycan and synthetic polymer materials for blood-contacting applications
ITMI20131193A1 (it) 2013-07-16 2015-01-17 Ira Srl Acido ialuronico reticolato, processo per la sua preparazione ed applicazioni in ambito estetico
ITUA20161822A1 (it) * 2016-03-18 2017-09-18 Indena Spa Composizioni utili nella prevenzione e/o nel trattamento di patologie del cavo orale, delle prime vie aeree e dell’esofago

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2312615A1 (de) * 1972-03-14 1973-09-27 Exploaterings Ab Tbf Verfahren zum kuppeln von verbindungen mit hydroxyl- und/oder aminogruppen an polymere
DE2627125A1 (de) * 1975-06-18 1976-12-30 Hayashibara Biochem Lab Vernetztes pullulan
DE2631908A1 (de) * 1975-07-15 1977-02-10 Massachusetts Inst Technology Vernetztes polymeres

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2312615A1 (de) * 1972-03-14 1973-09-27 Exploaterings Ab Tbf Verfahren zum kuppeln von verbindungen mit hydroxyl- und/oder aminogruppen an polymere
DE2627125A1 (de) * 1975-06-18 1976-12-30 Hayashibara Biochem Lab Vernetztes pullulan
DE2631908A1 (de) * 1975-07-15 1977-02-10 Massachusetts Inst Technology Vernetztes polymeres

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Acta. Chem. Scand., 1964, 18 (1), S.274-275 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3520008A1 (de) * 1984-12-06 1986-06-19 Biomatrix Inc Hyaluronsaeure-gele und -mischgele sowie verfahren zu deren herstellung
DE3607897A1 (de) * 1985-03-12 1986-09-18 Biomatrix Inc., Ridgefield, N.J. Verfahren zur herstellung einer chemisch modifizierten hyaluronsaeurezubereitung

Also Published As

Publication number Publication date
CA1238043A (en) 1988-06-14
FR2556728B1 (fr) 1987-06-26
GB8420560D0 (en) 1984-09-19
GB2151244A (en) 1985-07-17
IT8423225A1 (it) 1986-04-18
GB2151244B (en) 1987-01-07
FR2556728A1 (fr) 1985-06-21
IT8423225A0 (it) 1984-10-18
AU551628B2 (en) 1986-05-08
IT1178588B (it) 1987-09-09
AU3337984A (en) 1985-06-20
DE3434104C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1991-06-20

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Owner name: GENZYME BIOSURGERY CORPORATION, CAMBRIDGE, MASS.,