DE3048421C2 - Antibiotische Substanz, Verfahren zu deren Herstellung und antimykotisches Mittel, welches diese enthält - Google Patents

Antibiotische Substanz, Verfahren zu deren Herstellung und antimykotisches Mittel, welches diese enthält

Info

Publication number
DE3048421C2
DE3048421C2 DE3048421A DE3048421A DE3048421C2 DE 3048421 C2 DE3048421 C2 DE 3048421C2 DE 3048421 A DE3048421 A DE 3048421A DE 3048421 A DE3048421 A DE 3048421A DE 3048421 C2 DE3048421 C2 DE 3048421C2
Authority
DE
Germany
Prior art keywords
substance
methanol
reaction
acetone
soluble
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3048421A
Other languages
German (de)
English (en)
Other versions
DE3048421A1 (de
Inventor
Norio Ezaki
Shigeharu Yokohama Kanagawa Inouye
Tatsuo Isehara Kanagawa Ito
Michio Tokyo Kojima
Tomizo Yokohama Kanagawa Niwa
Takashi Shomura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Meiji Seika Kaisha Ltd
Original Assignee
Meiji Seika Kaisha Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Meiji Seika Kaisha Ltd filed Critical Meiji Seika Kaisha Ltd
Publication of DE3048421A1 publication Critical patent/DE3048421A1/de
Application granted granted Critical
Publication of DE3048421C2 publication Critical patent/DE3048421C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/42—Nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/465—Streptomyces

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrrole Compounds (AREA)
DE3048421A 1979-12-24 1980-12-22 Antibiotische Substanz, Verfahren zu deren Herstellung und antimykotisches Mittel, welches diese enthält Expired DE3048421C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16692679A JPS5690099A (en) 1979-12-24 1979-12-24 Novel antibiotic and its preparation

Publications (2)

Publication Number Publication Date
DE3048421A1 DE3048421A1 (de) 1981-10-15
DE3048421C2 true DE3048421C2 (de) 1983-03-24

Family

ID=15840213

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3048421A Expired DE3048421C2 (de) 1979-12-24 1980-12-22 Antibiotische Substanz, Verfahren zu deren Herstellung und antimykotisches Mittel, welches diese enthält

Country Status (7)

Country Link
US (1) US4376778A (https=)
JP (1) JPS5690099A (https=)
DE (1) DE3048421C2 (https=)
FR (1) FR2472611A1 (https=)
GB (1) GB2066816B (https=)
IT (1) IT1188979B (https=)
MX (1) MX6925E (https=)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5690099A (en) 1979-12-24 1981-07-21 Meiji Seika Kaisha Ltd Novel antibiotic and its preparation
DE3268983D1 (en) * 1981-10-07 1986-03-20 Meiji Seika Kaisha Heterocyclic compounds and antibacterial and antifungal compositions containing the same as active ingredients
US5204332A (en) * 1988-12-05 1993-04-20 American Cyanamid Company Pyrrole carbonitrile and nitropyrrole insecticidal and acaricidal and molluscicidal agents
BR8906202A (pt) * 1988-12-05 1990-09-25 American Cyanamid Co Processo e composicao para o controle de pragas de insetos,acaros e moluscos,composto para tal controle e processo para sua preparacao
US5162308A (en) * 1988-12-05 1992-11-10 American Cyanamid Company Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof
US5371239A (en) * 1989-12-22 1994-12-06 American Cyanamid Company Methods and compositions for protecting animals against attack and infestation by helminth, acarid and arthropod endo- and ectoparasites
JPH0641067A (ja) * 1992-04-20 1994-02-15 Kitasato Inst:The 新規カルパイン阻害物質ｋｐ−１２４１及びその製造法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL23184A (en) * 1964-03-25 1968-11-27 Fujisawa Pharmaceutical Co New antibiotic substance designated as pyrrolnitrin and production thereof
US3932458A (en) * 1971-11-04 1976-01-13 Sterling Drug Inc. Antimicrobial and plant-active 4,5-dihalopyrrole-2-carbonitriles
JPS5690099A (en) 1979-12-24 1981-07-21 Meiji Seika Kaisha Ltd Novel antibiotic and its preparation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Also Published As

Publication number Publication date
FR2472611B1 (https=) 1984-02-17
IT8050448A0 (it) 1980-12-23
JPS6220984B2 (https=) 1987-05-11
MX6925E (es) 1986-11-28
IT1188979B (it) 1988-01-28
FR2472611A1 (fr) 1981-07-03
JPS5690099A (en) 1981-07-21
US4376778A (en) 1983-03-15
DE3048421A1 (de) 1981-10-15
GB2066816B (en) 1984-01-18
GB2066816A (en) 1981-07-15
IT8050448A1 (it) 1982-06-23

Similar Documents

Publication Publication Date Title
DE2347682C2 (de) Rapamycin, Verfahren zu seiner Herstellung und pharmazeutisches Mittel
DE2754326C2 (de) Antibiotikum AM 2282, seine Herstellung und Arzneimittel
DE2532568A1 (de) Aclacinomycine a und b und verfahren zu ihrer herstellung
DE2743654C3 (https=)
DE2900591A1 (de) Antibiotica, ein verfahren zu ihrer herstellung sowie ihre verwendung als pflanzenschutzmittel
DE2344020C2 (de) Verfahren zur Herstellung des Antibiotikums Cephemimycin
DE3048421C2 (de) Antibiotische Substanz, Verfahren zu deren Herstellung und antimykotisches Mittel, welches diese enthält
DE2167325C2 (de) Antibiotikum A-201B und Verfahren zu seiner Herstellung
DE3012014C2 (de) Istamycine, Verfahren zu deren Herstellung sowie Verwendung derselben als antibakterielle Mittel
DE2746253C2 (de) Verfahren zur Herstellung von Maytansinol und dessen Derivaten
DE3003624A1 (de) Antibiotica c-19393 s tief 2 und h tief 2
DE2725163C2 (https=)
DE3041130C2 (https=)
DE1208449B (de) Verfahren zur Herstellung des Antibiotikums Ussamycin
DE69129924T2 (de) Antibiotikum und Verfahren zu seiner Herstellung
DE3003359C2 (https=)
DE2236599C3 (de) Fungizides Antibiotikum, sowie Herstellung und Verwendung desselben
DE2818544A1 (de) Antibiotikum sf-1942, verfahren zu dessen herstellung und pharmazeutische zusammensetzung, die das antibiotikum sf-1942 enthaelt
DE2444110A1 (de) Neues antibiotikum
DE3687189T2 (de) Antitumor- und antimikroben-verbindung, deren mikrobiologische herstellung und deren benutzung als arzneimittel.
DE1617768A1 (de) Neuartige antibiotische Polyoxine D,E,F,G und H und Verfahren zu ihrer Herstellung
DE2938993A1 (de) Herbicolin, verfahren zu seiner herstellung und es enthaltende mittel
DE1492111C (de) Verfahren zur Herstellung von Poly oxm A und B
DE1077380B (de) Herstellung des Antibiotikums Lemacidin
DE2905066C2 (de) Antibiotikum SF-2050B, Verfahren zur Herstellung desselben und antibakterielle Mittel, welche dasselbe enthalten

Legal Events

Date Code Title Description
OP8 Request for examination as to paragraph 44 patent law
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee