DE3017861C2 - Verfahren zur enzymatischen Herstellung von L-Tryptophan - Google Patents

Verfahren zur enzymatischen Herstellung von L-Tryptophan

Info

Publication number
DE3017861C2
DE3017861C2 DE3017861A DE3017861A DE3017861C2 DE 3017861 C2 DE3017861 C2 DE 3017861C2 DE 3017861 A DE3017861 A DE 3017861A DE 3017861 A DE3017861 A DE 3017861A DE 3017861 C2 DE3017861 C2 DE 3017861C2
Authority
DE
Germany
Prior art keywords
serine
tryptophan
reaction
racemase
tryptophanase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3017861A
Other languages
German (de)
English (en)
Other versions
DE3017861A1 (de
Inventor
Yoshiyuki Yokohama Kanagawa Asai
Masao Yamato Kanagawa Shimada
Kenji Uji Kyoto Soda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5564579A external-priority patent/JPS55148095A/ja
Priority claimed from JP7961979A external-priority patent/JPS565098A/ja
Priority claimed from JP3619780A external-priority patent/JPS56134992A/ja
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Publication of DE3017861A1 publication Critical patent/DE3017861A1/de
Application granted granted Critical
Publication of DE3017861C2 publication Critical patent/DE3017861C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE3017861A 1979-05-09 1980-05-09 Verfahren zur enzymatischen Herstellung von L-Tryptophan Expired DE3017861C2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP5564579A JPS55148095A (en) 1979-05-09 1979-05-09 Enzymatic preparation of l-tryptophan
JP7961979A JPS565098A (en) 1979-06-26 1979-06-26 Production of l-triptophane by use of enzyme
JP3619780A JPS56134992A (en) 1980-03-24 1980-03-24 Suppressing method of decomposition of serine

Publications (2)

Publication Number Publication Date
DE3017861A1 DE3017861A1 (de) 1981-01-22
DE3017861C2 true DE3017861C2 (de) 1984-11-22

Family

ID=27289013

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3017861A Expired DE3017861C2 (de) 1979-05-09 1980-05-09 Verfahren zur enzymatischen Herstellung von L-Tryptophan

Country Status (10)

Country Link
US (1) US4335209A (OSRAM)
AU (1) AU530435B2 (OSRAM)
CA (1) CA1128443A (OSRAM)
CH (1) CH642947A5 (OSRAM)
DE (1) DE3017861C2 (OSRAM)
FR (1) FR2456140A1 (OSRAM)
GB (1) GB2048266B (OSRAM)
IT (1) IT1145337B (OSRAM)
MX (1) MX6037E (OSRAM)
NL (1) NL8002603A (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3123937C2 (de) * 1980-06-17 1984-06-07 Asahi Kasei Kogyo K.K., Osaka Verfahren zur Herstellung von L-Tryptophan oder seiner Derivate
DE3134901A1 (de) * 1981-08-31 1983-03-17 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur extraktion von aromatischen aminosaeuren aus waessriger phase
US4600692A (en) * 1983-02-10 1986-07-15 Purification Engineering, Inc. Immobilized cells for preparing phenylalanine
US4710467A (en) * 1983-07-29 1987-12-01 Purification Engineering, Inc. Process for preparing phenylalanine
EP0217862A4 (en) * 1985-03-18 1989-12-28 Genex Corp IN VITRO SYNTHESIS PROCEDURE OF L-TRYPTOPHANE.
JPS62205781A (ja) * 1986-03-03 1987-09-10 Res Assoc Util Of Light Oil シユ−ドモナス属菌株の培養方法
DE3630878C1 (en) * 1986-09-11 1988-03-10 Amino Gmbh Process for the preparation of L-tryptophan and DL-serine
EP0299715A3 (en) * 1987-07-13 1990-07-04 MITSUI TOATSU CHEMICALS, Inc. Process for preparing L-tryptophan
US5525501A (en) * 1990-09-14 1996-06-11 Takeda Chemical Industries, Ltd. DNA Fragment encoding acylamino acid racemase
US5629202A (en) * 1994-07-19 1997-05-13 Development Center For Biotechnology Computer-controlled bioreactor system for enzymatic synthesis of L-tryptophan
JPH1142097A (ja) * 1997-01-09 1999-02-16 Daicel Chem Ind Ltd Ｄ−トリプトファンの製造方法
PL364984A1 (en) * 1999-01-19 2004-12-27 The Johns Hopkins University School Of Medicine Mammalian serine racemase
US6984484B1 (en) 1999-01-19 2006-01-10 The Johns Hopkins University Mammalian serine racemase
JP2001245689A (ja) 2000-03-09 2001-09-11 Ajinomoto Co Inc ハロ−ｌ−トリプトファンの製造法
EP1870454B1 (en) * 2005-03-18 2009-12-09 Kyowa Hakko Bio Co., Ltd. Process for producing dipeptides
CA3061340A1 (en) 2017-04-25 2018-11-01 Temple Otorongo Llc Pharmaceutical composition comprising tryptophan and phyllokinin derivative for use in treating psychiatric and psychological conditions
CN110878029A (zh) * 2019-11-13 2020-03-13 上海星酶生物科技有限公司 一种d-丝氨酸的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT989051B (it) * 1971-04-23 1975-05-20 Snam Progetti Procedimento per la produzione enzimatica di l triptofano
JPS5137353B2 (OSRAM) * 1973-12-29 1976-10-15
JPS51121597A (en) * 1975-04-11 1976-10-23 Ajinomoto Co Inc Process for producing tryptophan and its derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Also Published As

Publication number Publication date
GB2048266B (en) 1983-11-30
AU530435B2 (en) 1983-07-14
DE3017861A1 (de) 1981-01-22
IT1145337B (it) 1986-11-05
US4335209A (en) 1982-06-15
CA1128443A (en) 1982-07-27
FR2456140A1 (fr) 1980-12-05
IT8048605A0 (it) 1980-05-07
CH642947A5 (fr) 1984-05-15
NL8002603A (nl) 1980-11-11
GB2048266A (en) 1980-12-10
AU5797980A (en) 1980-11-13
MX6037E (es) 1984-10-08
FR2456140B1 (OSRAM) 1984-10-26

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Legal Events

Date Code Title Description
8180 Miscellaneous part 1

Free format text: DER ANMELDER LAUTET RICHTIG MITSUITOATSU CHEMICALS, INC., TOKYO, JP

8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee