CA1128443A - Process for the preparation of l-tryptophan by enzyme - Google Patents

Process for the preparation of l-tryptophan by enzyme

Info

Publication number
CA1128443A
CA1128443A CA350,695A CA350695A CA1128443A CA 1128443 A CA1128443 A CA 1128443A CA 350695 A CA350695 A CA 350695A CA 1128443 A CA1128443 A CA 1128443A
Authority
CA
Canada
Prior art keywords
serine
tryptophan
reaction
racemase
tryptophanase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA350,695A
Other languages
English (en)
French (fr)
Inventor
Yoshiyuki Asai
Kenji Soda
Masao Shimada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsui Toatsu Chemicals Inc
Original Assignee
Mitsui Toatsu Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP5564579A external-priority patent/JPS55148095A/ja
Priority claimed from JP7961979A external-priority patent/JPS565098A/ja
Priority claimed from JP3619780A external-priority patent/JPS56134992A/ja
Application filed by Mitsui Toatsu Chemicals Inc filed Critical Mitsui Toatsu Chemicals Inc
Application granted granted Critical
Publication of CA1128443A publication Critical patent/CA1128443A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
    • C12P13/227—Tryptophan

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA350,695A 1979-05-09 1980-04-25 Process for the preparation of l-tryptophan by enzyme Expired CA1128443A (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP5564579A JPS55148095A (en) 1979-05-09 1979-05-09 Enzymatic preparation of l-tryptophan
JP54-55645 1979-05-09
JP54-79619 1979-06-26
JP7961979A JPS565098A (en) 1979-06-26 1979-06-26 Production of l-triptophane by use of enzyme
JP55-36197 1980-03-24
JP3619780A JPS56134992A (en) 1980-03-24 1980-03-24 Suppressing method of decomposition of serine

Publications (1)

Publication Number Publication Date
CA1128443A true CA1128443A (en) 1982-07-27

Family

ID=27289013

Family Applications (1)

Application Number Title Priority Date Filing Date
CA350,695A Expired CA1128443A (en) 1979-05-09 1980-04-25 Process for the preparation of l-tryptophan by enzyme

Country Status (10)

Country Link
US (1) US4335209A (OSRAM)
AU (1) AU530435B2 (OSRAM)
CA (1) CA1128443A (OSRAM)
CH (1) CH642947A5 (OSRAM)
DE (1) DE3017861C2 (OSRAM)
FR (1) FR2456140A1 (OSRAM)
GB (1) GB2048266B (OSRAM)
IT (1) IT1145337B (OSRAM)
MX (1) MX6037E (OSRAM)
NL (1) NL8002603A (OSRAM)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3123937C2 (de) * 1980-06-17 1984-06-07 Asahi Kasei Kogyo K.K., Osaka Verfahren zur Herstellung von L-Tryptophan oder seiner Derivate
DE3134901A1 (de) * 1981-08-31 1983-03-17 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur extraktion von aromatischen aminosaeuren aus waessriger phase
US4600692A (en) * 1983-02-10 1986-07-15 Purification Engineering, Inc. Immobilized cells for preparing phenylalanine
US4710467A (en) * 1983-07-29 1987-12-01 Purification Engineering, Inc. Process for preparing phenylalanine
WO1986005515A1 (en) * 1985-03-18 1986-09-25 Genex Corporation In vitro synthesis of l-tryptophan
JPS62205781A (ja) * 1986-03-03 1987-09-10 Res Assoc Util Of Light Oil シユ−ドモナス属菌株の培養方法
DE3630878C1 (en) * 1986-09-11 1988-03-10 Amino Gmbh Process for the preparation of L-tryptophan and DL-serine
EP0299715A3 (en) * 1987-07-13 1990-07-04 MITSUI TOATSU CHEMICALS, Inc. Process for preparing L-tryptophan
US5525501A (en) * 1990-09-14 1996-06-11 Takeda Chemical Industries, Ltd. DNA Fragment encoding acylamino acid racemase
US5629202A (en) * 1994-07-19 1997-05-13 Development Center For Biotechnology Computer-controlled bioreactor system for enzymatic synthesis of L-tryptophan
JPH1142097A (ja) * 1997-01-09 1999-02-16 Daicel Chem Ind Ltd Ｄ−トリプトファンの製造方法
PL364984A1 (en) * 1999-01-19 2004-12-27 The Johns Hopkins University School Of Medicine Mammalian serine racemase
US6984484B1 (en) 1999-01-19 2006-01-10 The Johns Hopkins University Mammalian serine racemase
JP2001245689A (ja) * 2000-03-09 2001-09-11 Ajinomoto Co Inc ハロ−ｌ−トリプトファンの製造法
DE602006010990D1 (de) * 2005-03-18 2010-01-21 Kyowa Hakko Bio Co Ltd Verfahren zur dipeptidherstellung
EP3615053A4 (en) 2017-04-25 2021-07-14 Temple Otorongo LLC PHARMACEUTICAL COMPOSITION CONSISTING OF TRYPTOPHAN AND A PHYLLOKININ DERIVATIVE FOR USE IN THE TREATMENT OF PSYCHIATRIC AND PSYCHOLOGICAL DISORDERS
CN110878029A (zh) * 2019-11-13 2020-03-13 上海星酶生物科技有限公司 一种d-丝氨酸的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT989051B (it) * 1971-04-23 1975-05-20 Snam Progetti Procedimento per la produzione enzimatica di l triptofano
JPS5137353B2 (OSRAM) * 1973-12-29 1976-10-15
JPS51121597A (en) * 1975-04-11 1976-10-23 Ajinomoto Co Inc Process for producing tryptophan and its derivatives

Also Published As

Publication number Publication date
DE3017861C2 (de) 1984-11-22
DE3017861A1 (de) 1981-01-22
MX6037E (es) 1984-10-08
AU530435B2 (en) 1983-07-14
GB2048266B (en) 1983-11-30
GB2048266A (en) 1980-12-10
NL8002603A (nl) 1980-11-11
CH642947A5 (fr) 1984-05-15
AU5797980A (en) 1980-11-13
FR2456140B1 (OSRAM) 1984-10-26
IT1145337B (it) 1986-11-05
US4335209A (en) 1982-06-15
FR2456140A1 (fr) 1980-12-05
IT8048605A0 (it) 1980-05-07

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Legal Events

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