DE3017015A1 - Steroide, verfahren zu ihrer herstellung und sie enthaltende zubereitungen - Google Patents

Steroide, verfahren zu ihrer herstellung und sie enthaltende zubereitungen

Info

Publication number
DE3017015A1
DE3017015A1 DE19803017015 DE3017015A DE3017015A1 DE 3017015 A1 DE3017015 A1 DE 3017015A1 DE 19803017015 DE19803017015 DE 19803017015 DE 3017015 A DE3017015 A DE 3017015A DE 3017015 A1 DE3017015 A1 DE 3017015A1
Authority
DE
Germany
Prior art keywords
mmol
added
ether
compound
tetrahydrofuran
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
DE19803017015
Other languages
German (de)
English (en)
Other versions
DE3017015C2 (es
Inventor
Thomas R Blohm
Brian W Metcalf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richardson Vicks Inc
Original Assignee
Richardson Merrell Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richardson Merrell Inc filed Critical Richardson Merrell Inc
Publication of DE3017015A1 publication Critical patent/DE3017015A1/de
Application granted granted Critical
Publication of DE3017015C2 publication Critical patent/DE3017015C2/de
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19803017015 1979-05-02 1980-05-02 Steroide, verfahren zu ihrer herstellung und sie enthaltende zubereitungen Granted DE3017015A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3535779A 1979-05-02 1979-05-02
US6974179A 1979-08-27 1979-08-27

Publications (2)

Publication Number Publication Date
DE3017015A1 true DE3017015A1 (de) 1980-11-20
DE3017015C2 DE3017015C2 (es) 1989-04-20

Family

ID=26712031

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19803017015 Granted DE3017015A1 (de) 1979-05-02 1980-05-02 Steroide, verfahren zu ihrer herstellung und sie enthaltende zubereitungen

Country Status (16)

Country Link
AT (1) AT390794B (es)
AU (1) AU532558B2 (es)
CA (1) CA1154008A (es)
CH (1) CH643863A5 (es)
DE (1) DE3017015A1 (es)
DK (1) DK166501B1 (es)
ES (1) ES491010A0 (es)
FR (1) FR2455610A1 (es)
GB (1) GB2048888B (es)
IE (1) IE49704B1 (es)
IL (1) IL59934A (es)
IT (1) IT1188932B (es)
NL (1) NL191387C (es)
NO (1) NO154884C (es)
NZ (1) NZ193527A (es)
SE (1) SE448097B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT396239B (de) * 1985-02-15 1993-07-26 Erba Carlo Spa Verfahren zur herstellung von neuen in 4-stellung substituierten androstendionderivaten

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143909A (en) * 1991-03-19 1992-09-01 Merrell Dow Pharmaceuticals Inc. Aminosteroids in a method for inhibiting c17-20 lyase
NZ239141A (en) * 1990-08-01 1994-04-27 Merrell Dow Pharma 4-amino-delta-4,6-steroids; preparatory processes and pharmaceutical compositions
AU637247B2 (en) * 1990-08-01 1993-05-20 Merrell Dow Pharmaceuticals Inc. 4-amino-delta4-steroids and their use as 5alpha-reductase inhibitors
EP0794456B1 (en) 1996-03-07 2003-01-29 Agfa-Gevaert Method of reproducing an electronically stored medical image on a light-sensitive photographic material

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917829A (en) * 1971-11-08 1975-11-04 Research Corp Novel methods of inhibiting the activity of testosterone 5{60 -reductase
US4088760A (en) * 1976-06-23 1978-05-09 Richardson-Merrell Inc. Testosterone 5α-reductase inhibitors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917829A (en) * 1971-11-08 1975-11-04 Research Corp Novel methods of inhibiting the activity of testosterone 5{60 -reductase
US4088760A (en) * 1976-06-23 1978-05-09 Richardson-Merrell Inc. Testosterone 5α-reductase inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT396239B (de) * 1985-02-15 1993-07-26 Erba Carlo Spa Verfahren zur herstellung von neuen in 4-stellung substituierten androstendionderivaten

Also Published As

Publication number Publication date
FR2455610A1 (fr) 1980-11-28
FR2455610B1 (es) 1982-04-30
IT8048559A0 (it) 1980-04-30
NO154884B (no) 1986-09-29
IL59934A (en) 1983-06-15
NL191387B (nl) 1995-02-01
IE800806L (en) 1980-11-02
NO154884C (no) 1987-01-07
ES8105012A1 (es) 1981-05-16
AU532558B2 (en) 1983-10-06
NZ193527A (en) 1984-10-19
IL59934A0 (en) 1980-06-30
NL191387C (nl) 1995-07-03
IT1188932B (it) 1988-01-28
SE448097B (sv) 1987-01-19
IE49704B1 (en) 1985-11-27
GB2048888B (en) 1983-05-25
AU5774780A (en) 1980-11-06
AT390794B (de) 1990-06-25
NL8002529A (nl) 1980-11-04
CH643863A5 (de) 1984-06-29
NO801254L (no) 1980-11-03
IT8048559A1 (it) 1981-10-30
SE8003242L (sv) 1980-11-03
GB2048888A (en) 1980-12-17
DK194180A (da) 1980-11-03
ES491010A0 (es) 1981-05-16
DK166501B1 (da) 1993-06-01
DE3017015C2 (es) 1989-04-20
CA1154008A (en) 1983-09-20
ATA232880A (de) 1989-12-15

Similar Documents

Publication Publication Date Title
US4317817A (en) Novel steroid 5α-reductase inhibitors
DE3124780C2 (es)
DD298106A5 (de) 4-substituierte 17 beta-(cyclopropyloxy)-androst-5-en-3beta-ole und verwandte verbindungen, verfahren zu ihrer herstellung und ihre verwendung
DE2631915A1 (de) 16-dehydroandrostan-derivate
DE3017015C2 (es)
DE1253707B (de) Verfahren zur Herstellung von Steroiden der 9beta, 10alpha-Androstan oder Pregnanreih
DE2954699C2 (es)
CH621560A5 (en) Process for the preparation of 3-ketosteroids disubstituted in position 16
CH634083A5 (de) Verfahren zur herstellung neuer kortikoide.
DE2933258C2 (es)
DE2425822A1 (de) 17 beta-hydroxy-16,16-dimethyloestr-4en-3-on und verfahren zur herstellung desselben
DE1468985A1 (de) 17alpha-Alkyl-,17alpha-Alkenyl- und 17alpha-Alkinyl-4,5-epoxy-19-norandrostan-17beta-diole und deren Carbonsaeureester sowie Verfahren zur Herstellung dieser Verbindungen
DE2100319C3 (de) Neue Östranverbindungen, ihre Herstellung und sie enthaltende Arzneimittel
EP0225272A1 (de) 1-Methyl-15alpha-alkyl-androsta-1,4-dien-3,17-dione, Verf. zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE60026608T2 (de) 3-methylen steroid derivate zur behandlung von autoimmunerkrankungen
DD143912A5 (de) Verfahren zum aufbau der hydroxyacetyl-seitenkette von steroiden des pregnan-typs
DE2362718A1 (de) 2,2-dimethylsteroide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE1793677C3 (de) Verfahren zur Herstellung von 8-Hydroxygona-13r5(10)-trienen und 8-Hydroxygona-13,5(10),9(ll)-tetraenen und gewisse neue 8-Hydroxygona-133(10)-triene und 8-Hydroxygona-13Ä10),9(l l)-tetraene
DE2651364A1 (de) Neue d-homosteroide
DE2639600A1 (de) Neue 2,2-dimethylsteroide, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen
DE3040200A1 (de) Neue chlorierte acetylen-derivate des androst-4-en, deren herstellung, deren verwendung als arzneimittelund die sie enthaltenden zusammensetzungen
DE2223343C2 (de) 12ß-Alkylgonadiene und pharmazeutische Zusammensetzungen
DE1902641C3 (de) 3-Cyclopentyloxysteroide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE1793749C3 (de) Verfahren zur Herstellung von 1,4-Diensteroiden
DE2158260C3 (de) 11-Alkoxysteroide, Verfahren zu deren Herstellung sowie diese enthaltende pharmazeutische Zusammensetzungen

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition