IT1188932B - Composti steroidi inibitori di 5alfa-riduttasi e procedimento di preparazione - Google Patents

Composti steroidi inibitori di 5alfa-riduttasi e procedimento di preparazione

Info

Publication number
IT1188932B
IT1188932B IT48559/80A IT4855980A IT1188932B IT 1188932 B IT1188932 B IT 1188932B IT 48559/80 A IT48559/80 A IT 48559/80A IT 4855980 A IT4855980 A IT 4855980A IT 1188932 B IT1188932 B IT 1188932B
Authority
IT
Italy
Prior art keywords
5alpha
reductase inhibitor
preparation procedure
steroid compounds
inhibitor steroid
Prior art date
Application number
IT48559/80A
Other languages
English (en)
Italian (it)
Other versions
IT8048559A0 (it
IT8048559A1 (it
Inventor
Thomas R Blohm
Brian W Metcalf
Original Assignee
Merrell Inc Richard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Inc Richard filed Critical Merrell Inc Richard
Publication of IT8048559A0 publication Critical patent/IT8048559A0/it
Publication of IT8048559A1 publication Critical patent/IT8048559A1/it
Application granted granted Critical
Publication of IT1188932B publication Critical patent/IT1188932B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J1/00Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003Androstane derivatives
    • C07J1/0011Androstane derivatives substituted in position 17 by a keto group
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J17/00Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J21/00Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J3/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J31/00Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J51/00Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT48559/80A 1979-05-02 1980-04-30 Composti steroidi inibitori di 5alfa-riduttasi e procedimento di preparazione IT1188932B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3535779A 1979-05-02 1979-05-02
US6974179A 1979-08-27 1979-08-27

Publications (3)

Publication Number Publication Date
IT8048559A0 IT8048559A0 (it) 1980-04-30
IT8048559A1 IT8048559A1 (it) 1981-10-30
IT1188932B true IT1188932B (it) 1988-01-28

Family

ID=26712031

Family Applications (1)

Application Number Title Priority Date Filing Date
IT48559/80A IT1188932B (it) 1979-05-02 1980-04-30 Composti steroidi inibitori di 5alfa-riduttasi e procedimento di preparazione

Country Status (16)

Country Link
AT (1) AT390794B (es)
AU (1) AU532558B2 (es)
CA (1) CA1154008A (es)
CH (1) CH643863A5 (es)
DE (1) DE3017015A1 (es)
DK (1) DK166501B1 (es)
ES (1) ES491010A0 (es)
FR (1) FR2455610A1 (es)
GB (1) GB2048888B (es)
IE (1) IE49704B1 (es)
IL (1) IL59934A (es)
IT (1) IT1188932B (es)
NL (1) NL191387C (es)
NO (1) NO154884C (es)
NZ (1) NZ193527A (es)
SE (1) SE448097B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8503940D0 (en) * 1985-02-15 1985-03-20 Erba Farmitalia 4-substituted androstendione derivatives
US5143909A (en) * 1991-03-19 1992-09-01 Merrell Dow Pharmaceuticals Inc. Aminosteroids in a method for inhibiting c17-20 lyase
NZ239141A (en) * 1990-08-01 1994-04-27 Merrell Dow Pharma 4-amino-delta-4,6-steroids; preparatory processes and pharmaceutical compositions
AU637247B2 (en) * 1990-08-01 1993-05-20 Merrell Dow Pharmaceuticals Inc. 4-amino-delta4-steroids and their use as 5alpha-reductase inhibitors
EP0794456B1 (en) 1996-03-07 2003-01-29 Agfa-Gevaert Method of reproducing an electronically stored medical image on a light-sensitive photographic material

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917829A (en) * 1971-11-08 1975-11-04 Research Corp Novel methods of inhibiting the activity of testosterone 5{60 -reductase
US4088760A (en) * 1976-06-23 1978-05-09 Richardson-Merrell Inc. Testosterone 5α-reductase inhibitors

Also Published As

Publication number Publication date
FR2455610A1 (fr) 1980-11-28
FR2455610B1 (es) 1982-04-30
IT8048559A0 (it) 1980-04-30
NO154884B (no) 1986-09-29
IL59934A (en) 1983-06-15
NL191387B (nl) 1995-02-01
IE800806L (en) 1980-11-02
NO154884C (no) 1987-01-07
ES8105012A1 (es) 1981-05-16
AU532558B2 (en) 1983-10-06
NZ193527A (en) 1984-10-19
IL59934A0 (en) 1980-06-30
NL191387C (nl) 1995-07-03
SE448097B (sv) 1987-01-19
IE49704B1 (en) 1985-11-27
GB2048888B (en) 1983-05-25
AU5774780A (en) 1980-11-06
AT390794B (de) 1990-06-25
NL8002529A (nl) 1980-11-04
CH643863A5 (de) 1984-06-29
NO801254L (no) 1980-11-03
IT8048559A1 (it) 1981-10-30
SE8003242L (sv) 1980-11-03
GB2048888A (en) 1980-12-17
DK194180A (da) 1980-11-03
ES491010A0 (es) 1981-05-16
DK166501B1 (da) 1993-06-01
DE3017015C2 (es) 1989-04-20
DE3017015A1 (de) 1980-11-20
CA1154008A (en) 1983-09-20
ATA232880A (de) 1989-12-15

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Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19990430