DE2930070A1 - Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden aminosaeuren - Google Patents

Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden aminosaeuren

Info

Publication number
DE2930070A1
DE2930070A1 DE19792930070 DE2930070A DE2930070A1 DE 2930070 A1 DE2930070 A1 DE 2930070A1 DE 19792930070 DE19792930070 DE 19792930070 DE 2930070 A DE2930070 A DE 2930070A DE 2930070 A1 DE2930070 A1 DE 2930070A1
Authority
DE
Germany
Prior art keywords
substrate
membrane
formate
dehydrogenase
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19792930070
Other languages
German (de)
English (en)
Inventor
Andreas Dipl Ing Bueckmann
Maria-Regina Dipl Chem Dr Kula
Wolfgang Dipl C Leuchtenberger
Christian Prof Dipl Ch Wandrey
Rolf Dipl Chem Wichmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Evonik Operations GmbH
Original Assignee
Degussa GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa GmbH filed Critical Degussa GmbH
Priority to DE19792930070 priority Critical patent/DE2930070A1/de
Priority to SU802954169A priority patent/SU1069622A3/ru
Priority to DE8080104345T priority patent/DE3064127D1/de
Priority to CA000356910A priority patent/CA1139697A/en
Priority to EP80104345A priority patent/EP0023346B1/de
Priority to US06/172,446 priority patent/US4304858A/en
Priority to JP10144480A priority patent/JPS5664792A/ja
Publication of DE2930070A1 publication Critical patent/DE2930070A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/36—Dinucleotides, e.g. nicotineamide-adenine dinucleotide phosphate
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/813—Continuous fermentation

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19792930070 1979-07-25 1979-07-25 Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden aminosaeuren Withdrawn DE2930070A1 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
DE19792930070 DE2930070A1 (de) 1979-07-25 1979-07-25 Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden aminosaeuren
SU802954169A SU1069622A3 (ru) 1979-07-25 1980-07-24 Способ получени низших @ - @ -аминокислот
DE8080104345T DE3064127D1 (en) 1979-07-25 1980-07-24 Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding amino acids
CA000356910A CA1139697A (en) 1979-07-25 1980-07-24 PROCESS FOR THE CONTINUOUS ENZYMATIC CONVERSION OF WATER-SOLUBLE AND .alpha.-KETOCARBOXYLIC ACIDS INTO THE CORRESPONDING AMINO ACIDS
EP80104345A EP0023346B1 (de) 1979-07-25 1980-07-24 Verfahren zur kontinuierlichen enzymatischen Umwandlung von wasserlöslichen alpha-Ketocarbonsäuren in die entsprechenden Aminosäuren
US06/172,446 US4304858A (en) 1979-07-25 1980-07-25 Process for the continuous enzymatic change of water soluble α-ketocarboxylic acids into the corresponding amino acids
JP10144480A JPS5664792A (en) 1979-07-25 1980-07-25 Continuous enzymatic conversion of water soluble alphaaketocarboxylic acid to corresponding to amino acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792930070 DE2930070A1 (de) 1979-07-25 1979-07-25 Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden aminosaeuren

Publications (1)

Publication Number Publication Date
DE2930070A1 true DE2930070A1 (de) 1981-02-19

Family

ID=6076684

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19792930070 Withdrawn DE2930070A1 (de) 1979-07-25 1979-07-25 Verfahren zur kontinuierlichen enzymatischen umwandlung von wasserloeslichen alpha -ketocarbonsaeuren in die entsprechenden aminosaeuren
DE8080104345T Expired DE3064127D1 (en) 1979-07-25 1980-07-24 Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding amino acids

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8080104345T Expired DE3064127D1 (en) 1979-07-25 1980-07-24 Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding amino acids

Country Status (6)

Country Link
US (1) US4304858A (https=)
EP (1) EP0023346B1 (https=)
JP (1) JPS5664792A (https=)
CA (1) CA1139697A (https=)
DE (2) DE2930070A1 (https=)
SU (1) SU1069622A3 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772749A (en) * 1982-12-24 1988-09-20 Degussa Aktiengesellschaft Process for the recovery of malic acid

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4481292A (en) * 1980-07-01 1984-11-06 The Coca-Cola Company Process for the generation of acetaldehyde from ethanol
EP0076266B1 (en) * 1981-04-08 1988-11-09 GORTON, Lo Electrode for the electrochemical regeneration of co-enzyme, a method of making said electrode, and the use thereof
US4451566A (en) * 1981-12-04 1984-05-29 Spencer Donald B Methods and apparatus for enzymatically producing ethanol
US4600692A (en) * 1983-02-10 1986-07-15 Purification Engineering, Inc. Immobilized cells for preparing phenylalanine
DE3307094A1 (de) * 1983-03-01 1984-09-06 Degussa Ag, 6000 Frankfurt Verfahren zur kontinuierlichen enzymatischen umwandlung von (alpha)-hydroxycarbonsaeuren in entsprechende optisch aktive (alpha)-aminocarbonsaeuren
DE3307095A1 (de) * 1983-03-01 1984-09-06 Degussa Ag, 6000 Frankfurt Mikrobiologisch hergestellte l-phenylalanin-dehydrogenase, verfahren zu ihrer gewinnung und ihre verwendung
US4728611A (en) * 1983-07-29 1988-03-01 Purification Engineering, Inc. Production of phenylalanine with immobilized cells
KR850001802A (ko) * 1983-08-16 1985-04-01 월터 에이취. 드래거 박테리아에서 l-아미노산을 제조하는 방법
AU3187984A (en) * 1983-08-16 1985-02-21 Genentech Inc. Recombinant process for preparing l-amino acids
US4525454A (en) * 1983-09-01 1985-06-25 Genetics Institute, Inc. Production of L-4-phenyl-2-aminobutanoic acid by transamination
US4518692A (en) * 1983-09-01 1985-05-21 Genetics Institute, Inc. Production of L-amino acids by transamination
JPS60184393A (ja) * 1984-03-02 1985-09-19 Ajinomoto Co Inc アラニンの製造法
US4657862A (en) * 1984-07-31 1987-04-14 International Flavors & Fragrances Inc. Preparation of naturally-occurring C2-C5 alkyl esters of C4-C5 carboxylic acids by means of fermentation of C5-C6 amino acids in the presence of C2-C5 alcohols
JPS6198962U (https=) * 1984-12-05 1986-06-25
DE3446304A1 (de) * 1984-12-19 1986-07-10 Degussa Ag, 6000 Frankfurt Verfahren zur gewinnung von phenylalanin-dehydrogenase enthaltenden mikroorganismen, mikroorganismen, die in ihnen enthaltene phenylalanin-dehydrogenase und deren verwendung zur herstellung von l-(alpha)-aminosaeuren
JPS61185194A (ja) * 1985-02-13 1986-08-18 Mitsui Toatsu Chem Inc アミノ酸の生産法
JPS61185195A (ja) * 1985-02-13 1986-08-18 Mitsui Toatsu Chem Inc アミノ酸の製造法
JPS6236196A (ja) * 1985-04-15 1987-02-17 Ajinomoto Co Inc アラニンの製造法
US4849345A (en) * 1985-04-17 1989-07-18 Sagami Chemical Research Center L-phenylalanine dehydrogenase and use thereof
FR2583432B1 (fr) * 1985-06-13 1988-11-04 Inst Francais Du Petrole Procede de production enzymatique de l-a-aminoacides a partir d'a-cetoacides
JPS6261594A (ja) * 1985-09-11 1987-03-18 Kuraray Co Ltd Ｌ−フエニルアラニンの製造方法
US4826766A (en) * 1985-09-23 1989-05-02 Genetics Institute, Inc. Production of amino acids using coupled aminotransferases
DE3733198A1 (de) * 1987-10-01 1989-04-13 Kernforschungsanlage Juelich Enzymatisches verfahren zur herstellung von dipeptiden
DE3842025A1 (de) * 1988-12-14 1990-07-05 Hoechst Ag Verfahren zur herstellung von l-phosphinothricin
CA2008702A1 (en) * 1989-02-27 1990-08-27 Ronald L. Hanson Process for transformation of hydroxyketo acids to hydroxyamino acids
WO1992005268A1 (fr) * 1990-09-20 1992-04-02 Nippon Steel Corporation PROCEDE DE PRODUCTION DE L-β-HALOALANINE
ES2100819B1 (es) * 1995-11-27 1997-12-16 Univ Murcia Metodo de rentencion de nad (p) (h) en estado nativo con membranas de ultrafiltracion no cargadas.
US6432688B1 (en) * 1999-01-18 2002-08-13 Daicel Chemical Industries, Ltd. Amino alcohol dehydrogenase converts keto alcohol to amino alcohol and amino alcohol to keto alcohol
DE19926770A1 (de) 1999-06-11 2000-12-14 Basf Ag Nukleinsäurefragment und Vektor, enthaltend eine Halogenase, sowie ein Verfahren zur Halogenierung chemischer Verbindungen
WO2011035978A1 (de) 2009-09-23 2011-03-31 Basf Se Oligosaccharide und deren herstellung durch saure hydrolyse von stärke
EP3330380A1 (en) * 2016-12-05 2018-06-06 Evonik Degussa GmbH Process for producing l-methionine from methional

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3183170A (en) * 1961-10-03 1965-05-11 Sanraku Ocean Kabushiki Kaisha Method of l-amino acid manufacture
DE2008842A1 (de) * 1969-02-27 1970-11-05 Kyowa Hakko Kogyo Co., Ltd., Tokio Verfahren und Vorrichtung zur kontinuierlichen Durchführung von Enzymreaktionen
FR2217296A1 (en) * 1972-10-10 1974-09-06 Inst Francais Du Petrole Organic cpds. prepn. by co-enzymatic reduction - with continuous regeneration of the oxidised coenzyme with a reducing agent
US3915799A (en) * 1974-07-05 1975-10-28 Dow Chemical Co Method of minimizing cofactor loss in enzymatic reactors
IL46178A (en) * 1974-12-03 1978-10-31 Rehovot Res Prod Method for the performance of enzymatic reactions
FR2398046A1 (fr) * 1977-07-18 1979-02-16 Inst Francais Du Petrole Synthese enzymatique de la l-carnitine
US4251631A (en) * 1978-02-23 1981-02-17 Research Products Rehovot Ltd. Cross-linked enzyme membrane

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772749A (en) * 1982-12-24 1988-09-20 Degussa Aktiengesellschaft Process for the recovery of malic acid

Also Published As

Publication number Publication date
JPH022595B2 (https=) 1990-01-18
EP0023346A3 (en) 1981-05-13
DE3064127D1 (en) 1983-08-18
SU1069622A3 (ru) 1984-01-23
CA1139697A (en) 1983-01-18
US4304858A (en) 1981-12-08
EP0023346B1 (de) 1983-07-13
EP0023346A2 (de) 1981-02-04
JPS5664792A (en) 1981-06-02

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Legal Events

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8139 Disposal/non-payment of the annual fee