FR2217296A1 - Organic cpds. prepn. by co-enzymatic reduction - with continuous regeneration of the oxidised coenzyme with a reducing agent - Google Patents

Organic cpds. prepn. by co-enzymatic reduction - with continuous regeneration of the oxidised coenzyme with a reducing agent

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Publication number
FR2217296A1
FR2217296A1 FR7235901A FR7235901A FR2217296A1 FR 2217296 A1 FR2217296 A1 FR 2217296A1 FR 7235901 A FR7235901 A FR 7235901A FR 7235901 A FR7235901 A FR 7235901A FR 2217296 A1 FR2217296 A1 FR 2217296A1
Authority
FR
France
Prior art keywords
acid
prepn
imine
reducing agent
aldehyde
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7235901A
Other languages
French (fr)
Other versions
FR2217296B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IFP Energies Nouvelles IFPEN
Original Assignee
IFP Energies Nouvelles IFPEN
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IFP Energies Nouvelles IFPEN filed Critical IFP Energies Nouvelles IFPEN
Priority to FR7235901A priority Critical patent/FR2217296A1/en
Publication of FR2217296A1 publication Critical patent/FR2217296A1/en
Application granted granted Critical
Publication of FR2217296B1 publication Critical patent/FR2217296B1/fr
Granted legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/14Glutamic acid; Glutamine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56Lactic acid

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The matls. reduced contain aldehyde, ketone, acid, imine, quinone, quinone-imine, hydroxy acid, hydroxy aldehyde gps., and are reduced by an enzyme and a coreactor (I) (coenzyme) which is regenerated by redn. with cpd. (II) contg. alcohol, aldehyde, acid, imine, thiol functions. (I) is nicotinamide adenin dinucleotide (phosphate) or flavin adenin dinucleotide. (II) is an alcohol (ethanol) in presence of ethanol dehydrogenase. pH of reaction mixt. is 8.0-9.0, reaction temp. is room temp. -40 degrees C. The process is used for reductive amination of alpha-ketoglutaric acid or pyruvic acid, or reductive carboxylation of amino acetone.
FR7235901A 1972-10-10 1972-10-10 Organic cpds. prepn. by co-enzymatic reduction - with continuous regeneration of the oxidised coenzyme with a reducing agent Granted FR2217296A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7235901A FR2217296A1 (en) 1972-10-10 1972-10-10 Organic cpds. prepn. by co-enzymatic reduction - with continuous regeneration of the oxidised coenzyme with a reducing agent

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7235901A FR2217296A1 (en) 1972-10-10 1972-10-10 Organic cpds. prepn. by co-enzymatic reduction - with continuous regeneration of the oxidised coenzyme with a reducing agent

Publications (2)

Publication Number Publication Date
FR2217296A1 true FR2217296A1 (en) 1974-09-06
FR2217296B1 FR2217296B1 (en) 1975-03-28

Family

ID=9105450

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7235901A Granted FR2217296A1 (en) 1972-10-10 1972-10-10 Organic cpds. prepn. by co-enzymatic reduction - with continuous regeneration of the oxidised coenzyme with a reducing agent

Country Status (1)

Country Link
FR (1) FR2217296A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0023346A2 (en) * 1979-07-25 1981-02-04 Degussa Aktiengesellschaft Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding amino acids
EP0024547A2 (en) * 1979-07-25 1981-03-11 Degussa Aktiengesellschaft Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding alpha-hydroxy carbonic acids
EP0034213A1 (en) * 1980-02-13 1981-08-26 Ivan Endre Modrovich A stabilized aqueous coenzyme solution for use in a clinical assay, a method of stabilizing a labile coenzyme in an aqueous clinical assay solution and a kit for use in said clinical assay
EP0118750A2 (en) * 1983-02-09 1984-09-19 Phillips Petroleum Company Regeneration of NAD(P) cofactor
FR2583432A1 (en) * 1985-06-13 1986-12-19 Inst Francais Du Petrole PROCESS FOR THE ENZYMATIC PRODUCTION OF L-A-AMINO ACIDS FROM A-KETOACIDES
EP0215414A2 (en) * 1985-09-09 1987-03-25 Kuraray Co., Ltd. Process for producing L-phenylalanine

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Cited By (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0023346A2 (en) * 1979-07-25 1981-02-04 Degussa Aktiengesellschaft Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding amino acids
EP0024547A2 (en) * 1979-07-25 1981-03-11 Degussa Aktiengesellschaft Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding alpha-hydroxy carbonic acids
EP0024547A3 (en) * 1979-07-25 1981-05-06 Degussa Aktiengesellschaft Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding alpha-hydroxy carbonic acids
EP0023346A3 (en) * 1979-07-25 1981-05-13 Degussa Aktiengesellschaft Process for the continuous enzymatic transformation of water-soluble alpha-keto carbonic acids into the corresponding amino acids
EP0034213A1 (en) * 1980-02-13 1981-08-26 Ivan Endre Modrovich A stabilized aqueous coenzyme solution for use in a clinical assay, a method of stabilizing a labile coenzyme in an aqueous clinical assay solution and a kit for use in said clinical assay
EP0118750A3 (en) * 1983-02-09 1986-02-05 Phillips Petroleum Company Regeneration of nad(p) cofactor
EP0118750A2 (en) * 1983-02-09 1984-09-19 Phillips Petroleum Company Regeneration of NAD(P) cofactor
FR2583432A1 (en) * 1985-06-13 1986-12-19 Inst Francais Du Petrole PROCESS FOR THE ENZYMATIC PRODUCTION OF L-A-AMINO ACIDS FROM A-KETOACIDES
EP0206904A2 (en) * 1985-06-13 1986-12-30 Institut Français du Pétrole Process for the enzymatic production of L-alpha amino acids from alpha keto acids
EP0206904A3 (en) * 1985-06-13 1989-03-08 Institut Francais Du Petrole Process for the enzymatic production of l-alpha amino acids from alpha keto acids
EP0215414A2 (en) * 1985-09-09 1987-03-25 Kuraray Co., Ltd. Process for producing L-phenylalanine
EP0215414A3 (en) * 1985-09-09 1988-05-04 Kuraray Co., Ltd. Process for producing l-phenylalanine
US5420023A (en) * 1985-09-09 1995-05-30 Kuraray Co., Ltd. Process for producing L-phenylalanine

Also Published As

Publication number Publication date
FR2217296B1 (en) 1975-03-28

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