DE2900961A1 - Cephalosporine und verfahren zu deren herstellung - Google Patents

Cephalosporine und verfahren zu deren herstellung

Info

Publication number
DE2900961A1
DE2900961A1 DE19792900961 DE2900961A DE2900961A1 DE 2900961 A1 DE2900961 A1 DE 2900961A1 DE 19792900961 DE19792900961 DE 19792900961 DE 2900961 A DE2900961 A DE 2900961A DE 2900961 A1 DE2900961 A1 DE 2900961A1
Authority
DE
Germany
Prior art keywords
oxo
salt
group
ppm
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19792900961
Other languages
German (de)
English (en)
Inventor
Akira Morimoto
Michihiko Ochiai
Taiiti Okada
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DE2900961A1 publication Critical patent/DE2900961A1/de
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19792900961 1978-01-13 1979-01-11 Cephalosporine und verfahren zu deren herstellung Ceased DE2900961A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP303278A JPS5498795A (en) 1978-01-13 1978-01-13 Cephalosporin derivative and its preparation

Publications (1)

Publication Number Publication Date
DE2900961A1 true DE2900961A1 (de) 1979-07-19

Family

ID=11545964

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19792900961 Ceased DE2900961A1 (de) 1978-01-13 1979-01-11 Cephalosporine und verfahren zu deren herstellung

Country Status (6)

Country Link
JP (1) JPS5498795A (fr)
CH (1) CH642662A5 (fr)
DE (1) DE2900961A1 (fr)
FR (1) FR2414508A1 (fr)
GB (1) GB2012276B (fr)
IT (1) IT1111686B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030294A2 (fr) * 1979-11-21 1981-06-17 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Procédé de préparation de dérivés de céphalosporine; intermédiaires et leur préparation
US4465831A (en) * 1980-12-24 1984-08-14 Isf S.P.A. Ketoiminocephalosporin derivatives
EP0336202A1 (fr) * 1988-03-24 1989-10-11 Hoechst Aktiengesellschaft Procédé de préparation d'esters de l'acide 4-halo-3-oxo-2-alkoximinobutyrique
WO2004083216A1 (fr) * 2003-03-20 2004-09-30 Orchid Chemicals & Pharmaceuticals Ltd Procede de preparation de cephalosporines

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0009671B1 (fr) * 1978-09-12 1984-06-13 Fujisawa Pharmaceutical Co., Ltd. Produits de départ pour la préparation de composés du type céphem et procédé pour leur préparation
JPS56125392A (en) * 1980-03-06 1981-10-01 Fujisawa Pharmaceut Co Ltd Cepham and cephem compound and preparation thereof
JPS5984890A (ja) * 1982-11-05 1984-05-16 Hisayasu Ishimaru 経口用セフアロスポリン化合物
GB8410991D0 (en) * 1984-04-30 1984-06-06 Glaxo Group Ltd Process
JPS60260583A (ja) * 1985-05-14 1985-12-23 Sankyo Co Ltd セフアロスポリン誘導体の製法
WO1987003585A1 (fr) * 1985-12-06 1987-06-18 Mect Corporation 4-halo-2-hydroxyimino-3-oxobutyronitriles et leur procede de preparation
JPH0830051B2 (ja) * 1986-05-21 1996-03-27 武田薬品工業株式会社 ４−ハロゲノ−２−置換オキシイミノ−３−オキソ酪酸のエステルまたはアミドの製造法
EP0257275A3 (fr) * 1986-07-28 1990-05-23 American Cyanamid Company Dérivés de céphalosporine et de pénicilline
JPH01230547A (ja) * 1988-01-14 1989-09-14 Takeda Chem Ind Ltd ３−オキソ酪酸第三ブチルの製造法及びその用途
JP2595605B2 (ja) * 1988-01-18 1997-04-02 武田薬品工業株式会社 ２−置換オキシイミノ−３−オキソ酪酸の製造法
JPH0393762A (ja) * 1989-09-04 1991-04-18 Wako Pure Chem Ind Ltd ４‐ハロゲノ‐２‐アルコキシイミノ‐３‐オキソ脂肪酸の製造方法
IN192139B (fr) 2001-11-26 2004-02-21 Lupin Ltd
WO2005019227A1 (fr) * 2003-08-22 2005-03-03 Orchid Chemicals & Pharmaceuticals Ltd Procede de preparation d'un antibiotique a base de cephalosporine
US20050119244A1 (en) 2003-12-02 2005-06-02 Acs Dobfar S.P.A. Process for preparing cephalosporins with salified intermediate
KR100904068B1 (ko) 2007-09-04 2009-06-23 제일모직주식회사 컬러필터용 감광성 수지 조성물 및 이를 이용한 컬러필터

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2702501A1 (de) * 1976-01-23 1977-07-28 Roussel Uclaf Neue oxime der 7-aminothiazolylacetamidocephalosporansaeure, herstellungsverfahren und pharmazeutische zusammensetzungen
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2728766A1 (de) * 1976-06-28 1978-01-05 Fujisawa Pharmaceutical Co 2-niedrigalkyl-7-substituierte-2- oder -3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2707565A1 (de) * 1976-04-12 1978-02-23 Fujisawa Pharmaceutical Co Syn-isomere von 3,7-disubstituierten-3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
DE2810922A1 (de) * 1977-03-14 1978-09-21 Fujisawa Pharmaceutical Co Neue cephem- und cepham-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1576625A (en) * 1976-04-12 1980-10-08 Fujisawa Pharmaceutical Co Syn isomer 3,7 disubstituted 3 cephem 4 carboxylic acid compounds and processes for the preparation thereof

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2702501A1 (de) * 1976-01-23 1977-07-28 Roussel Uclaf Neue oxime der 7-aminothiazolylacetamidocephalosporansaeure, herstellungsverfahren und pharmazeutische zusammensetzungen
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
DE2707565A1 (de) * 1976-04-12 1978-02-23 Fujisawa Pharmaceutical Co Syn-isomere von 3,7-disubstituierten-3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische mittel
DE2715385A1 (de) * 1976-04-14 1977-11-10 Takeda Chemical Industries Ltd Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2728766A1 (de) * 1976-06-28 1978-01-05 Fujisawa Pharmaceutical Co 2-niedrigalkyl-7-substituierte-2- oder -3-cephem-4-carbonsaeureverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2810922A1 (de) * 1977-03-14 1978-09-21 Fujisawa Pharmaceutical Co Neue cephem- und cepham-verbindungen, verfahren zu ihrer herstellung und sie enthaltende arzneimittel

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0030294A2 (fr) * 1979-11-21 1981-06-17 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Procédé de préparation de dérivés de céphalosporine; intermédiaires et leur préparation
EP0030294A3 (en) * 1979-11-21 1981-12-09 F. Hoffmann-La Roche & Co. Aktiengesellschaft Process for the preparation of cephalosporin derivatives; intermediates in that process, and their preparation
US4465831A (en) * 1980-12-24 1984-08-14 Isf S.P.A. Ketoiminocephalosporin derivatives
EP0336202A1 (fr) * 1988-03-24 1989-10-11 Hoechst Aktiengesellschaft Procédé de préparation d'esters de l'acide 4-halo-3-oxo-2-alkoximinobutyrique
WO2004083216A1 (fr) * 2003-03-20 2004-09-30 Orchid Chemicals & Pharmaceuticals Ltd Procede de preparation de cephalosporines

Also Published As

Publication number Publication date
FR2414508A1 (fr) 1979-08-10
FR2414508B1 (fr) 1983-05-27
CH642662A5 (de) 1984-04-30
GB2012276A (en) 1979-07-25
GB2012276B (en) 1982-05-06
IT1111686B (it) 1986-01-13
JPS5498795A (en) 1979-08-03
JPH0142955B2 (fr) 1989-09-18
IT7919262A0 (it) 1979-01-12

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection