DE2853002A1 - Polypeptide und verfahren zu ihrer herstellung - Google Patents

Polypeptide und verfahren zu ihrer herstellung

Info

Publication number
DE2853002A1
DE2853002A1 DE19782853002 DE2853002A DE2853002A1 DE 2853002 A1 DE2853002 A1 DE 2853002A1 DE 19782853002 DE19782853002 DE 19782853002 DE 2853002 A DE2853002 A DE 2853002A DE 2853002 A1 DE2853002 A1 DE 2853002A1
Authority
DE
Germany
Prior art keywords
group
amino
protected
polymer
glutamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782853002
Other languages
German (de)
English (en)
Inventor
Gideon Goldstein
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ortho Pharmaceutical Corp
Original Assignee
Ortho Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/960,550 external-priority patent/US4232008A/en
Application filed by Ortho Pharmaceutical Corp filed Critical Ortho Pharmaceutical Corp
Publication of DE2853002A1 publication Critical patent/DE2853002A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1002Tetrapeptides with the first amino acid being neutral
    • C07K5/1005Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/1008Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1021Tetrapeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C07K7/062Serum thymic factor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE19782853002 1977-12-08 1978-12-07 Polypeptide und verfahren zu ihrer herstellung Withdrawn DE2853002A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US85849677A 1977-12-08 1977-12-08
US94053178A 1978-09-08 1978-09-08
US05/960,550 US4232008A (en) 1978-11-17 1978-11-17 Tetrapeptides and methods

Publications (1)

Publication Number Publication Date
DE2853002A1 true DE2853002A1 (de) 1979-06-13

Family

ID=27420392

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782853002 Withdrawn DE2853002A1 (de) 1977-12-08 1978-12-07 Polypeptide und verfahren zu ihrer herstellung

Country Status (19)

Country Link
JP (1) JPS5498719A (it)
CA (1) CA1120031A (it)
CH (1) CH642058A5 (it)
DE (1) DE2853002A1 (it)
DK (1) DK149595C (it)
ES (1) ES475857A1 (it)
FI (1) FI67368C (it)
FR (1) FR2411174A1 (it)
GB (1) GB2014581B (it)
GR (1) GR65013B (it)
IE (1) IE47611B1 (it)
IL (1) IL56150A (it)
IT (1) IT1110889B (it)
NL (1) NL7812004A (it)
NO (1) NO149631C (it)
NZ (1) NZ189101A (it)
PT (1) PT68883A (it)
SE (1) SE444687B (it)
YU (1) YU41322B (it)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0016612A2 (en) * 1979-03-14 1980-10-01 Ortho Pharmaceutical Corporation Peptides having ubiquitin-like activity, process for their preparation, therapeutic compositions containing them and their use
EP0026464A2 (de) * 1979-09-28 1981-04-08 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Peptide, deren Herstellung, deren Verwendung und pharmazeutische Präparate

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4215112A (en) * 1979-03-14 1980-07-29 Ortho Pharmaceutical Corporation Tripeptides and methods
CA1156220A (en) * 1979-04-26 1983-11-01 George Heavner Method and composition for preparation of h-sar-lys-sar-gln-nh.sub.2
JPS5711950A (en) 1980-06-25 1982-01-21 Kureha Chem Ind Co Ltd Peptide and its synthesis
FR2546164B1 (fr) * 1983-05-16 1987-07-17 Centre Nat Rech Scient Nouveaux derives de peptides, leur preparation et leur application comme inhibiteurs de l'elastase
FR2741076B1 (fr) * 1995-11-15 1998-01-30 Rech De Pathologie Appliquee S Conjugues peptidiques derives des hormones thymiques, leur utilisation a titre de medicament et compositions les contenant
RU2210382C1 (ru) * 2002-07-09 2003-08-20 Терентьев Александр Александрович Пептид, обладающий иммунорегуляторным свойством, и его композиция

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2822951A1 (de) * 1977-05-25 1978-12-21 Anvar Neue polypeptide mit thymusaktivitaet oder antagonistischer aktivitaet und verfahren zu ihrer herstellung

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2544348C3 (de) * 1975-10-03 1979-12-13 Max-Planck-Gesellschaft Zur Foerderung Der Wissenschaften E.V., 3400 Goettingen L-Leucin-13-Motilin, Verfahren zu dessen Herstellung und dasselbe enthaltendes Mittel
FR2423481A2 (fr) * 1978-04-21 1979-11-16 Anvar Nouveaux polypeptides a activite thymique ou a activite antagoniste et leurs procedes de synthese
FR2391994A1 (fr) * 1977-05-25 1978-12-22 Anvar Nouveaux polypeptides a activite thymique ou a activite antagoniste et leurs procedes de synthese

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2822951A1 (de) * 1977-05-25 1978-12-21 Anvar Neue polypeptide mit thymusaktivitaet oder antagonistischer aktivitaet und verfahren zu ihrer herstellung

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0016612A2 (en) * 1979-03-14 1980-10-01 Ortho Pharmaceutical Corporation Peptides having ubiquitin-like activity, process for their preparation, therapeutic compositions containing them and their use
EP0016612A3 (en) * 1979-03-14 1981-01-07 Ortho Pharmaceutical Corporation Peptides having ubiquitin-like activity, process for their preparation ,therapeutic compositions containing them and methods for their use
EP0026464A2 (de) * 1979-09-28 1981-04-08 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Peptide, deren Herstellung, deren Verwendung und pharmazeutische Präparate
EP0026464A3 (de) * 1979-09-28 1981-05-20 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Peptide, deren Herstellung, deren Verwendung und pharmazeutische Präparate

Also Published As

Publication number Publication date
YU41322B (en) 1987-02-28
IL56150A0 (en) 1979-03-12
PT68883A (en) 1979-01-01
CH642058A5 (de) 1984-03-30
GR65013B (en) 1980-06-12
NO149631C (no) 1984-05-23
GB2014581A (en) 1979-08-30
SE444687B (sv) 1986-04-28
ES475857A1 (es) 1980-01-16
IT1110889B (it) 1986-01-06
DK554078A (da) 1979-06-09
FR2411174A1 (fr) 1979-07-06
NO784128L (no) 1979-06-11
CA1120031A (en) 1982-03-16
YU288078A (en) 1983-02-28
DK149595C (da) 1987-03-23
DK149595B (da) 1986-08-04
FR2411174B1 (it) 1984-05-25
JPS6327360B2 (it) 1988-06-02
NZ189101A (en) 1984-07-06
SE7812614L (sv) 1979-06-09
IT7852239A0 (it) 1978-12-07
NL7812004A (nl) 1979-06-12
JPS5498719A (en) 1979-08-03
NO149631B (no) 1984-02-13
IL56150A (en) 1982-02-28
FI67368B (fi) 1984-11-30
FI67368C (fi) 1985-03-11
IE782423L (en) 1979-06-08
GB2014581B (en) 1982-05-19
FI783769A (fi) 1979-06-09
IE47611B1 (en) 1984-05-02

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Legal Events

Date Code Title Description
8128 New person/name/address of the agent

Representative=s name: GRUENECKER, A., DIPL.-ING. KINKELDEY, H., DIPL.-IN

8110 Request for examination paragraph 44
8139 Disposal/non-payment of the annual fee