DE2833505A1 - Tetrahydro-isochinolin-derivate, verfahren zu deren herstellung und mittel enthaltend die derivate - Google Patents

Tetrahydro-isochinolin-derivate, verfahren zu deren herstellung und mittel enthaltend die derivate

Info

Publication number
DE2833505A1
DE2833505A1 DE19782833505 DE2833505A DE2833505A1 DE 2833505 A1 DE2833505 A1 DE 2833505A1 DE 19782833505 DE19782833505 DE 19782833505 DE 2833505 A DE2833505 A DE 2833505A DE 2833505 A1 DE2833505 A1 DE 2833505A1
Authority
DE
Germany
Prior art keywords
compound
radicals
general formula
methoxy
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782833505
Other languages
German (de)
English (en)
Inventor
Sara Ginsburg
Richard J Kitz
John J Savarese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of DE2833505A1 publication Critical patent/DE2833505A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DE19782833505 1977-08-01 1978-07-31 Tetrahydro-isochinolin-derivate, verfahren zu deren herstellung und mittel enthaltend die derivate Withdrawn DE2833505A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82079477A 1977-08-01 1977-08-01

Publications (1)

Publication Number Publication Date
DE2833505A1 true DE2833505A1 (de) 1979-04-05

Family

ID=25231743

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782833505 Withdrawn DE2833505A1 (de) 1977-08-01 1978-07-31 Tetrahydro-isochinolin-derivate, verfahren zu deren herstellung und mittel enthaltend die derivate

Country Status (21)

Country Link
JP (1) JPS5455577A (xx)
AT (1) AT368496B (xx)
AU (1) AU523706B2 (xx)
BE (1) BE869415A (xx)
CA (1) CA1113096A (xx)
DD (1) DD143254A5 (xx)
DE (1) DE2833505A1 (xx)
DK (1) DK339078A (xx)
ES (1) ES472229A1 (xx)
FI (1) FI782363A (xx)
FR (1) FR2399429A1 (xx)
GB (1) GB2002758B (xx)
IE (1) IE47014B1 (xx)
IL (1) IL55254A (xx)
LU (1) LU80062A1 (xx)
MC (1) MC1197A1 (xx)
NL (1) NL7808067A (xx)
PL (1) PL121492B1 (xx)
SE (1) SE7808267L (xx)
SU (1) SU862820A3 (xx)
ZA (1) ZA784331B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235906A (en) 1978-07-21 1980-11-25 Massachusetts General Hospital Bis-isoquinolinium compounds, compositions and methods of use
CA1125287A (en) * 1978-07-21 1982-06-08 John J. Savarese Bis isoquinolinium compositions and methods of use
JPS5645459A (en) * 1979-09-20 1981-04-25 Otsuka Pharmaceut Co Ltd Cyclic amine
JPS5899465A (ja) * 1981-11-23 1983-06-13 ザ・ウエルカム・フアウンデ−シヨン・リミテツド イソキノリン誘導体
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
JPH0555438A (ja) * 1991-08-26 1993-03-05 Rohm Co Ltd 電子部品のリード端子構造
CA2284802C (en) * 1997-03-25 2009-06-16 Cornell Research Foundation, Inc. Substituted isoquinolines as ultra short acting neuromuscular blockers
US8148398B2 (en) * 2006-12-06 2012-04-03 Cornell Research Foundation, Inc. Intermediate duration neuromuscular blocking agents and antagonists thereof
WO2010107488A1 (en) 2009-03-17 2010-09-23 Cornell University Reversible nondepolarizing neuromuscular blockade agents and methods for their use
US9220700B2 (en) 2009-08-19 2015-12-29 Cornell University Cysteine for physiological injection
CN114057642B (zh) * 2021-12-10 2023-03-28 广东嘉博制药有限公司 一种米库氯铵中间体的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5156762U (xx) * 1974-10-28 1976-05-04

Also Published As

Publication number Publication date
SE7808267L (sv) 1979-02-02
JPS5455577A (en) 1979-05-02
FI782363A (fi) 1979-02-02
AT368496B (de) 1982-10-11
DD143254A5 (de) 1980-08-13
ES472229A1 (es) 1979-03-16
GB2002758A (en) 1979-02-28
IL55254A (en) 1983-03-31
BE869415A (fr) 1979-01-31
MC1197A1 (fr) 1979-03-19
GB2002758B (en) 1982-02-03
IE781550L (en) 1979-02-01
AU3847678A (en) 1980-02-07
DK339078A (da) 1979-02-02
IL55254A0 (en) 1978-09-29
FR2399429B1 (xx) 1981-07-17
AU523706B2 (en) 1982-08-12
FR2399429A1 (fr) 1979-03-02
CA1113096A (en) 1981-11-24
LU80062A1 (fr) 1979-05-15
PL208757A1 (pl) 1979-06-04
SU862820A3 (ru) 1981-09-07
IE47014B1 (en) 1983-11-30
PL121492B1 (en) 1982-05-31
NL7808067A (nl) 1979-02-05
ATA555478A (de) 1982-02-15
ZA784331B (en) 1979-12-27

Similar Documents

Publication Publication Date Title
DE3026201A1 (de) Aminoaetheroxide, verfahren zu ihrer herstellung sowie ihre therapeutische verwendung
DE2833505A1 (de) Tetrahydro-isochinolin-derivate, verfahren zu deren herstellung und mittel enthaltend die derivate
DE2006978C3 (de) N- [l-(3-Trifluonnetnyl-phenyl)-propyl-(2)] -glycinderivate, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE1911464C3 (de) 3,4-Dihydroisochinoline, Verfahren zu ihrer Herstellung und Arzneimittel
DE2426149A1 (de) Fluor-substituierte phenthiazine
DE2458638C2 (de) 4'-substituierte 2-Methyl-3-piperidinopropiophenonderivate, Verfahren zu deren Herstellung und pharmakologische Zubereitungen, welche diese enthalten
DE2449205C2 (de) Substituierte Furylverbindungen, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE1518452B2 (de) 4-substituierte 2-benzhydryl-2butanol-derivate und verfahren zu ihrer herstellung
DE2724478C2 (de) 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2802453B2 (de) Derivate des 3-[(3-Alkyl-5-isochinolyl)-imino]-1,5,10,10a-tetrahydro-thiazolo [3,4-b] zu isochinolins, ihre Herstellung und die sie enthaltenden Zusammensetzungen
DE2117358B2 (de) 4'-Aminomethyl-spiro eckige Klammer auf dibenzo eckige Klammer auf a,d eckige Klammer zu cycloheptadi-(oder tri-) en-5,2*-(r,3'-dioxolan) eckige Klammer zu -Derivate, Verfahren zu deren Herstellung und diese Verbindungen enthaltene Arzneimittel
DE2717001A1 (de) Arzneimittel mit antithrombotischer wirkung
DE2427272C3 (de) 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum
DE2903917C2 (xx)
DD142547A5 (de) Verfahren zur herstellung von als neuromuskulaere blockierungsmittel verwendbaren verbindungen
DE2101691A1 (de) Isochinolinderivate
DE2318575A1 (de) Neue oxazolidinone
DE2327193C3 (de) N-(Diethylaminoethyl)-2-methoxy-5methylsulfonylbenzamid, seine Salze, Verfahren zur Herstellung dieser Verbindungen sowie diese Verbindungen enthaltende Arzneimittel
DE2013256C (xx)
DE887649C (de) Verfahren zur Herstellung von als Spasmolytika geeigneten ungesaettigten Aminen
DE2164988C3 (de) 2,2-Diphenylcyclopropancarbonsäureesterderivate, Verfahren zu ihrer Herstellung und sie enthaltende Arzneimittel
DE2265580C2 (de) Heptamethylenimino-alkyl-xanthen-9-carbonsäureester, deren Säureadditionssalze und Verfahren zu deren Herstellung, sowie Arzneimittel, welche diese enthalten
DE1595870A1 (de) Verfahren zur Herstellung von 3-(o-Methoxyphenoxy)-1,2-propandiolnicotinaten und deren Salzen
AT265530B (de) Verfahren zur Herstellung von neuen Isochinolinderivaten
DE1056611B (de) Verfahren zur Herstellung von Phenthiazinderivaten

Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee
8128 New person/name/address of the agent

Representative=s name: SCHWABE, H., DIPL.-ING. SANDMAIR, K., DIPL.-CHEM.