JPS5645459A - Cyclic amine - Google Patents

Cyclic amine

Info

Publication number
JPS5645459A
JPS5645459A JP12153179A JP12153179A JPS5645459A JP S5645459 A JPS5645459 A JP S5645459A JP 12153179 A JP12153179 A JP 12153179A JP 12153179 A JP12153179 A JP 12153179A JP S5645459 A JPS5645459 A JP S5645459A
Authority
JP
Japan
Prior art keywords
formula
lower alkyl
cyclic amine
halogen
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP12153179A
Other languages
Japanese (ja)
Other versions
JPH0144711B2 (en
Inventor
Tatsuya Shono
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP12153179A priority Critical patent/JPS5645459A/en
Publication of JPS5645459A publication Critical patent/JPS5645459A/en
Publication of JPH0144711B2 publication Critical patent/JPH0144711B2/ja
Granted legal-status Critical Current

Links

Abstract

NEW MATERIAL:A cyclic amine expressed by formula I [R1 is H or lower alkyl; R2 is formula II (R is lower alkyl) or formula III; A is formula IV or V], and a salt thereof.
EXAMPLE: 1-( 3,4,5-Trimethoxybenzyl )-1,2,3,4-tetrahydro-2-methyl-6,7,8-trimethoxyquinoline.
USE: A branchodilator, an antitussive, an ameliorant of cerebral circulation and a preventing agent of premature birth having a smooth muscle relaxing action.
PROCESS: A compound expressed by formula VI (Z- is anion) is electrolytically reduced in the presence of a compound expressed by the formula R2X [X is halogen or R3SO3-(R3 is lower alkyl or aryl which may have a halogen as a substituent)] to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP12153179A 1979-09-20 1979-09-20 Cyclic amine Granted JPS5645459A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12153179A JPS5645459A (en) 1979-09-20 1979-09-20 Cyclic amine

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12153179A JPS5645459A (en) 1979-09-20 1979-09-20 Cyclic amine

Publications (2)

Publication Number Publication Date
JPS5645459A true JPS5645459A (en) 1981-04-25
JPH0144711B2 JPH0144711B2 (en) 1989-09-29

Family

ID=14813532

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12153179A Granted JPS5645459A (en) 1979-09-20 1979-09-20 Cyclic amine

Country Status (1)

Country Link
JP (1) JPS5645459A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4570089A (en) * 1982-05-27 1986-02-11 Tokyo Shibaura Denki Kabushiki Kaisha Pulse frequency multiplier

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52102281A (en) * 1976-02-24 1977-08-27 Tanabe Seiyaku Co Ltd Tetrahydroisoquinoline derivatives
JPS53130437A (en) * 1977-04-18 1978-11-14 Helm Karl O Pharmaceutical composition
JPS5455577A (en) * 1977-08-01 1979-05-02 Masachiyuusetsutsu Gen Hosupit Blocking agent of neuromuscle

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52102281A (en) * 1976-02-24 1977-08-27 Tanabe Seiyaku Co Ltd Tetrahydroisoquinoline derivatives
JPS53130437A (en) * 1977-04-18 1978-11-14 Helm Karl O Pharmaceutical composition
JPS5455577A (en) * 1977-08-01 1979-05-02 Masachiyuusetsutsu Gen Hosupit Blocking agent of neuromuscle

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4570089A (en) * 1982-05-27 1986-02-11 Tokyo Shibaura Denki Kabushiki Kaisha Pulse frequency multiplier

Also Published As

Publication number Publication date
JPH0144711B2 (en) 1989-09-29

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