JPS5645459A - Cyclic amine - Google Patents
Cyclic amineInfo
- Publication number
- JPS5645459A JPS5645459A JP12153179A JP12153179A JPS5645459A JP S5645459 A JPS5645459 A JP S5645459A JP 12153179 A JP12153179 A JP 12153179A JP 12153179 A JP12153179 A JP 12153179A JP S5645459 A JPS5645459 A JP S5645459A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- lower alkyl
- cyclic amine
- halogen
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Abstract
NEW MATERIAL:A cyclic amine expressed by formula I [R1 is H or lower alkyl; R2 is formula II (R is lower alkyl) or formula III; A is formula IV or V], and a salt thereof.
EXAMPLE: 1-( 3,4,5-Trimethoxybenzyl )-1,2,3,4-tetrahydro-2-methyl-6,7,8-trimethoxyquinoline.
USE: A branchodilator, an antitussive, an ameliorant of cerebral circulation and a preventing agent of premature birth having a smooth muscle relaxing action.
PROCESS: A compound expressed by formula VI (Z- is anion) is electrolytically reduced in the presence of a compound expressed by the formula R2X [X is halogen or R3SO3-(R3 is lower alkyl or aryl which may have a halogen as a substituent)] to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12153179A JPS5645459A (en) | 1979-09-20 | 1979-09-20 | Cyclic amine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP12153179A JPS5645459A (en) | 1979-09-20 | 1979-09-20 | Cyclic amine |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5645459A true JPS5645459A (en) | 1981-04-25 |
JPH0144711B2 JPH0144711B2 (en) | 1989-09-29 |
Family
ID=14813532
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP12153179A Granted JPS5645459A (en) | 1979-09-20 | 1979-09-20 | Cyclic amine |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5645459A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4570089A (en) * | 1982-05-27 | 1986-02-11 | Tokyo Shibaura Denki Kabushiki Kaisha | Pulse frequency multiplier |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52102281A (en) * | 1976-02-24 | 1977-08-27 | Tanabe Seiyaku Co Ltd | Tetrahydroisoquinoline derivatives |
JPS53130437A (en) * | 1977-04-18 | 1978-11-14 | Helm Karl O | Pharmaceutical composition |
JPS5455577A (en) * | 1977-08-01 | 1979-05-02 | Masachiyuusetsutsu Gen Hosupit | Blocking agent of neuromuscle |
-
1979
- 1979-09-20 JP JP12153179A patent/JPS5645459A/en active Granted
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52102281A (en) * | 1976-02-24 | 1977-08-27 | Tanabe Seiyaku Co Ltd | Tetrahydroisoquinoline derivatives |
JPS53130437A (en) * | 1977-04-18 | 1978-11-14 | Helm Karl O | Pharmaceutical composition |
JPS5455577A (en) * | 1977-08-01 | 1979-05-02 | Masachiyuusetsutsu Gen Hosupit | Blocking agent of neuromuscle |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4570089A (en) * | 1982-05-27 | 1986-02-11 | Tokyo Shibaura Denki Kabushiki Kaisha | Pulse frequency multiplier |
Also Published As
Publication number | Publication date |
---|---|
JPH0144711B2 (en) | 1989-09-29 |
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