JPS5649391A - Novel bis- 8h-pyrrolo- 3,2-e -s-triazolo- 1,5-a - pyrimidinomethyl amine derivative - Google Patents

Novel bis- 8h-pyrrolo- 3,2-e -s-triazolo- 1,5-a - pyrimidinomethyl amine derivative

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Publication number
JPS5649391A
JPS5649391A JP12494279A JP12494279A JPS5649391A JP S5649391 A JPS5649391 A JP S5649391A JP 12494279 A JP12494279 A JP 12494279A JP 12494279 A JP12494279 A JP 12494279A JP S5649391 A JPS5649391 A JP S5649391A
Authority
JP
Japan
Prior art keywords
triazolo
pyrimidinomethyl
pyrrolo
amine derivative
alkylamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP12494279A
Other languages
Japanese (ja)
Inventor
Haruo Onishi
Koji Kojiyaku
Yasuo Suzuki
Suguru Mochida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mochida Pharmaceutical Co Ltd
Original Assignee
Mochida Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharmaceutical Co Ltd filed Critical Mochida Pharmaceutical Co Ltd
Priority to JP12494279A priority Critical patent/JPS5649391A/en
Publication of JPS5649391A publication Critical patent/JPS5649391A/en
Pending legal-status Critical Current

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  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:The titled compound of formula (R is 1W6C alkyl) and its salt.
EXAMPLE: Bis-2{ 5-methyl-8-( 3-methylbutyl )-6,7-dihydro-8H-pyrrolo-[ 3,2-e ]-s- triazolo-[1,5-a]-pyrimidinomethyl}3-methylbutylamine.
USE: Drugs having vasodilating, hypotensive, blood platelet coagulation inhibiting and cholesterol lowering activities. Effective to improve the disorder of the circulatory systems in general. Easily soluble in water.
PROCESS: The compound of formula can be prepared, e.g. by (1) reacting 2-halomethyl-5-methyl-6-(2-haloethyl)-7-halo-s-triazolo-[1,5-a]pyrimidine with an alkylamine, (2) adding the above halogen derivative to the reaction product to continue the reaction, and (3) reacting the reaction product with an alkylamine.
COPYRIGHT: (C)1981,JPO&Japio
JP12494279A 1979-09-28 1979-09-28 Novel bis- 8h-pyrrolo- 3,2-e -s-triazolo- 1,5-a - pyrimidinomethyl amine derivative Pending JPS5649391A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP12494279A JPS5649391A (en) 1979-09-28 1979-09-28 Novel bis- 8h-pyrrolo- 3,2-e -s-triazolo- 1,5-a - pyrimidinomethyl amine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12494279A JPS5649391A (en) 1979-09-28 1979-09-28 Novel bis- 8h-pyrrolo- 3,2-e -s-triazolo- 1,5-a - pyrimidinomethyl amine derivative

Publications (1)

Publication Number Publication Date
JPS5649391A true JPS5649391A (en) 1981-05-02

Family

ID=14897998

Family Applications (1)

Application Number Title Priority Date Filing Date
JP12494279A Pending JPS5649391A (en) 1979-09-28 1979-09-28 Novel bis- 8h-pyrrolo- 3,2-e -s-triazolo- 1,5-a - pyrimidinomethyl amine derivative

Country Status (1)

Country Link
JP (1) JPS5649391A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7425559B2 (en) 2001-07-13 2008-09-16 Btg International Limited Medicine containing pyrimidine derivative

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7425559B2 (en) 2001-07-13 2008-09-16 Btg International Limited Medicine containing pyrimidine derivative
US8288399B2 (en) 2001-07-13 2012-10-16 Btg International Limited Medicine containing pyrimidine derivative

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