JPS57122071A - 1,4-benzothiazine compound - Google Patents
1,4-benzothiazine compoundInfo
- Publication number
- JPS57122071A JPS57122071A JP56008492A JP849281A JPS57122071A JP S57122071 A JPS57122071 A JP S57122071A JP 56008492 A JP56008492 A JP 56008492A JP 849281 A JP849281 A JP 849281A JP S57122071 A JPS57122071 A JP S57122071A
- Authority
- JP
- Japan
- Prior art keywords
- halogen
- compound
- dihydro
- methoxy
- phenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The 2-phenyl-2,3-dihydro-1,4-benzothiazine compound of formula I(R is H, lower alkyl, or lower aralkyl; Y is H, halogen or methoxy; R and Y are not H at the same time) and its salt.
EXAMPLE: 4-Ethyl-2-phenyl-2, 3-dihydro-1, 4-benzothiazine.
USE: Analgesic agent, etc. It exhibits strong activity to suppress the coagulation of blood platelet or activity to inhibit the contraction of the extracted intestine.
PROCESS: The compound of formulaIwherein R is H and Y is halogen or methoxy can be prepared by reacting the α-halogenophenylacetyl halogenide of formula II (X is halogen; Y' is halogen or methoxy) with o-aminothiophenol, and reducing the resultant 2-phenyl 2,3-dihydro-1,4-benzothiazin-3-one compound of formula III.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56008492A JPS57122071A (en) | 1981-01-21 | 1981-01-21 | 1,4-benzothiazine compound |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP56008492A JPS57122071A (en) | 1981-01-21 | 1981-01-21 | 1,4-benzothiazine compound |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57122071A true JPS57122071A (en) | 1982-07-29 |
Family
ID=11694610
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP56008492A Pending JPS57122071A (en) | 1981-01-21 | 1981-01-21 | 1,4-benzothiazine compound |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57122071A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60166674A (en) * | 1984-02-09 | 1985-08-29 | Santen Pharmaceut Co Ltd | Benzothiazine derivative |
-
1981
- 1981-01-21 JP JP56008492A patent/JPS57122071A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60166674A (en) * | 1984-02-09 | 1985-08-29 | Santen Pharmaceut Co Ltd | Benzothiazine derivative |
JPH0568470B2 (en) * | 1984-02-09 | 1993-09-29 | Santen Pharmaceutical Co Ltd |
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