JPS56108760A - Propionic acid derivative and its preparation - Google Patents

Propionic acid derivative and its preparation

Info

Publication number
JPS56108760A
JPS56108760A JP1183880A JP1183880A JPS56108760A JP S56108760 A JPS56108760 A JP S56108760A JP 1183880 A JP1183880 A JP 1183880A JP 1183880 A JP1183880 A JP 1183880A JP S56108760 A JPS56108760 A JP S56108760A
Authority
JP
Japan
Prior art keywords
formula
propionic acid
compound
methoxyphenyl
acid derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1183880A
Other languages
Japanese (ja)
Other versions
JPS6058909B2 (en
Inventor
Shigeto Nagao
Mitsunori Gaino
Norio Takamura
Masanori Sato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to JP55011838A priority Critical patent/JPS6058909B2/en
Publication of JPS56108760A publication Critical patent/JPS56108760A/en
Publication of JPS6058909B2 publication Critical patent/JPS6058909B2/en
Expired legal-status Critical Current

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NEW MATERIAL:A propionic acid derivative of formula I (R1 is methoxyphenyl; R2 is H or lower aliphatic acyl; R3 is H or lower alkyl) or a salt thereof.
EXAMPLE: 2-Hydroxy-3-p-methoxyphenyl-3- [ o-[ 2-( dimethylamino ) ethylamino ] phenyl]thiopropionic acid.
USE: A hypotensive agent.
PROCESS: A 2-hydroxy-3-methoxyphenyl-3-(o-aminophenyl)thio-propionic acid compound of formula II (R4 is a protecting group of the amino group) having the protected amino group is reacted with a dimethylaminoethyl halide of formula III (X1 is halogen) to give a thio-propionic acid compound of formula IV. The protecting group of the amino group is then removed from the compound of formula IV to afford the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP55011838A 1980-02-01 1980-02-01 Propionic acid derivatives and their production method Expired JPS6058909B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP55011838A JPS6058909B2 (en) 1980-02-01 1980-02-01 Propionic acid derivatives and their production method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55011838A JPS6058909B2 (en) 1980-02-01 1980-02-01 Propionic acid derivatives and their production method

Publications (2)

Publication Number Publication Date
JPS56108760A true JPS56108760A (en) 1981-08-28
JPS6058909B2 JPS6058909B2 (en) 1985-12-23

Family

ID=11788868

Family Applications (1)

Application Number Title Priority Date Filing Date
JP55011838A Expired JPS6058909B2 (en) 1980-02-01 1980-02-01 Propionic acid derivatives and their production method

Country Status (1)

Country Link
JP (1) JPS6058909B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0609031A1 (en) * 1993-01-27 1994-08-03 Shionogi & Co., Ltd. Process for preparing benzothiazepine derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0609031A1 (en) * 1993-01-27 1994-08-03 Shionogi & Co., Ltd. Process for preparing benzothiazepine derivatives
CN1040751C (en) * 1993-01-27 1998-11-18 盐野义制药株式会社 Process for preparation benzothiazepine derivatives

Also Published As

Publication number Publication date
JPS6058909B2 (en) 1985-12-23

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