JPS56115792A - Novel phosphorus compound and antitumor agent containing the same - Google Patents
Novel phosphorus compound and antitumor agent containing the sameInfo
- Publication number
- JPS56115792A JPS56115792A JP1793980A JP1793980A JPS56115792A JP S56115792 A JPS56115792 A JP S56115792A JP 1793980 A JP1793980 A JP 1793980A JP 1793980 A JP1793980 A JP 1793980A JP S56115792 A JPS56115792 A JP S56115792A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- antitumor agent
- phosphorus compound
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A phosphorus compound of formula I [R1 is H, alkyl, alkenyl, etc.; R2 is H, OH, SH, etc.; A1 is lower alkylene; X is group of formula VI (R3 and R4 are alkyl, aralkyl, etc.), etc.; Z is H, alkyl, aryl, etc.; Y1 is O or S; Y2 is OH or O-; l is 0, 1 or 2], its salt and its hydrate.
EXAMPLE: 2-( N-Cetyl-N-trimethylammonioacetylamino )ethyl-2'-hydroxyethyl phosphate monohydrate.
USE: Antitumor agent having immune activation effect to the host as well as the cytocidal activity.
PROCESS: For example, the compound of formula I is prepared by (1) reacting a compound of formula II with a compound of formula III (T1 and T2 are halogen) to obtain a compound of formula IV, (2) hydrolyzing the product, and (3) aminating the resulting compound of formula V.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1793980A JPS56115792A (en) | 1980-02-18 | 1980-02-18 | Novel phosphorus compound and antitumor agent containing the same |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1793980A JPS56115792A (en) | 1980-02-18 | 1980-02-18 | Novel phosphorus compound and antitumor agent containing the same |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56115792A true JPS56115792A (en) | 1981-09-11 |
JPS6320238B2 JPS6320238B2 (en) | 1988-04-26 |
Family
ID=11957742
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1793980A Granted JPS56115792A (en) | 1980-02-18 | 1980-02-18 | Novel phosphorus compound and antitumor agent containing the same |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56115792A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5348670A (en) * | 1990-05-18 | 1994-09-20 | The Elco Corporation | Phosphorous amine lubricant additives |
-
1980
- 1980-02-18 JP JP1793980A patent/JPS56115792A/en active Granted
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5348670A (en) * | 1990-05-18 | 1994-09-20 | The Elco Corporation | Phosphorous amine lubricant additives |
Also Published As
Publication number | Publication date |
---|---|
JPS6320238B2 (en) | 1988-04-26 |
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