JPS56115792A - Novel phosphorus compound and antitumor agent containing the same - Google Patents

Novel phosphorus compound and antitumor agent containing the same

Info

Publication number
JPS56115792A
JPS56115792A JP1793980A JP1793980A JPS56115792A JP S56115792 A JPS56115792 A JP S56115792A JP 1793980 A JP1793980 A JP 1793980A JP 1793980 A JP1793980 A JP 1793980A JP S56115792 A JPS56115792 A JP S56115792A
Authority
JP
Japan
Prior art keywords
formula
compound
antitumor agent
phosphorus compound
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1793980A
Other languages
Japanese (ja)
Other versions
JPS6320238B2 (en
Inventor
Hiroshi Kodama
Masao Nakabayashi
Yoshifumi Nakajima
Takashi Nagai
Mikio Kawabata
Isao Myokan
Tetsuya Kajita
Masaaki Shibata
Kiyoshi Goda
Takashi Sano
Hiroko Ohashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Toyama Chemical Co Ltd
Original Assignee
Toyama Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd
Priority to JP1793980A priority Critical patent/JPS56115792A/en
Publication of JPS56115792A publication Critical patent/JPS56115792A/en
Publication of JPS6320238B2 publication Critical patent/JPS6320238B2/ja
Granted legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A phosphorus compound of formula I [R1 is H, alkyl, alkenyl, etc.; R2 is H, OH, SH, etc.; A1 is lower alkylene; X is group of formula VI (R3 and R4 are alkyl, aralkyl, etc.), etc.; Z is H, alkyl, aryl, etc.; Y1 is O or S; Y2 is OH or O-; l is 0, 1 or 2], its salt and its hydrate.
EXAMPLE: 2-( N-Cetyl-N-trimethylammonioacetylamino )ethyl-2'-hydroxyethyl phosphate monohydrate.
USE: Antitumor agent having immune activation effect to the host as well as the cytocidal activity.
PROCESS: For example, the compound of formula I is prepared by (1) reacting a compound of formula II with a compound of formula III (T1 and T2 are halogen) to obtain a compound of formula IV, (2) hydrolyzing the product, and (3) aminating the resulting compound of formula V.
COPYRIGHT: (C)1981,JPO&Japio
JP1793980A 1980-02-18 1980-02-18 Novel phosphorus compound and antitumor agent containing the same Granted JPS56115792A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1793980A JPS56115792A (en) 1980-02-18 1980-02-18 Novel phosphorus compound and antitumor agent containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1793980A JPS56115792A (en) 1980-02-18 1980-02-18 Novel phosphorus compound and antitumor agent containing the same

Publications (2)

Publication Number Publication Date
JPS56115792A true JPS56115792A (en) 1981-09-11
JPS6320238B2 JPS6320238B2 (en) 1988-04-26

Family

ID=11957742

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1793980A Granted JPS56115792A (en) 1980-02-18 1980-02-18 Novel phosphorus compound and antitumor agent containing the same

Country Status (1)

Country Link
JP (1) JPS56115792A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348670A (en) * 1990-05-18 1994-09-20 The Elco Corporation Phosphorous amine lubricant additives

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5348670A (en) * 1990-05-18 1994-09-20 The Elco Corporation Phosphorous amine lubricant additives

Also Published As

Publication number Publication date
JPS6320238B2 (en) 1988-04-26

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