JPS5683419A - Remedy for hypertension - Google Patents
Remedy for hypertensionInfo
- Publication number
- JPS5683419A JPS5683419A JP16098779A JP16098779A JPS5683419A JP S5683419 A JPS5683419 A JP S5683419A JP 16098779 A JP16098779 A JP 16098779A JP 16098779 A JP16098779 A JP 16098779A JP S5683419 A JPS5683419 A JP S5683419A
- Authority
- JP
- Japan
- Prior art keywords
- hypertension
- remedy
- sulfamoylbenzoylthio
- proline
- chloro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Thiazole And Isothizaole Compounds (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:A compound of formula (X is -CH2- or -S-; R1 is H when X is -CH2, or H or aryl when X is -S-; R2 is H or lower alkyl), or its salt.
EXAMPLE: 1-[ 3-( 4-Chloro-3-sulfamoylbenzoylthio )-2(S)-methylpropionyl ]-L-proline.
USE: A remedy for hypertension effective to essential hypertension, renal hypertension, malignant hypertension, etc.
PROCESS: The exemplified compound can be prepared e.g. by reacting 3-(4-chloro-3- sulfamoylbenzoylthio)-2(S)-methylpropionyl chloride with L-proline in the presence of sodium bicarbonate and water.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16098779A JPS5683419A (en) | 1979-12-11 | 1979-12-11 | Remedy for hypertension |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16098779A JPS5683419A (en) | 1979-12-11 | 1979-12-11 | Remedy for hypertension |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5683419A true JPS5683419A (en) | 1981-07-08 |
JPS642568B2 JPS642568B2 (en) | 1989-01-18 |
Family
ID=15726408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16098779A Granted JPS5683419A (en) | 1979-12-11 | 1979-12-11 | Remedy for hypertension |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5683419A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4464371A (en) * | 1980-12-29 | 1984-08-07 | Santen Pharmaceutical Co., Ltd. | Five-membered heterocyclic compounds |
JPH053703U (en) * | 1991-07-01 | 1993-01-22 | 三菱農機株式会社 | Transmission of work vehicle |
-
1979
- 1979-12-11 JP JP16098779A patent/JPS5683419A/en active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4464371A (en) * | 1980-12-29 | 1984-08-07 | Santen Pharmaceutical Co., Ltd. | Five-membered heterocyclic compounds |
JPH053703U (en) * | 1991-07-01 | 1993-01-22 | 三菱農機株式会社 | Transmission of work vehicle |
Also Published As
Publication number | Publication date |
---|---|
JPS642568B2 (en) | 1989-01-18 |
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