JPS5683419A - Remedy for hypertension - Google Patents

Remedy for hypertension

Info

Publication number
JPS5683419A
JPS5683419A JP16098779A JP16098779A JPS5683419A JP S5683419 A JPS5683419 A JP S5683419A JP 16098779 A JP16098779 A JP 16098779A JP 16098779 A JP16098779 A JP 16098779A JP S5683419 A JPS5683419 A JP S5683419A
Authority
JP
Japan
Prior art keywords
hypertension
remedy
sulfamoylbenzoylthio
proline
chloro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16098779A
Other languages
Japanese (ja)
Other versions
JPS642568B2 (en
Inventor
Katsuo Arimura
Osamu Murakami
Taichi Oka
Kunio Osuge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Welfide Corp
Original Assignee
Welfide Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Welfide Corp filed Critical Welfide Corp
Priority to JP16098779A priority Critical patent/JPS5683419A/en
Publication of JPS5683419A publication Critical patent/JPS5683419A/en
Publication of JPS642568B2 publication Critical patent/JPS642568B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:A compound of formula (X is -CH2- or -S-; R1 is H when X is -CH2, or H or aryl when X is -S-; R2 is H or lower alkyl), or its salt.
EXAMPLE: 1-[ 3-( 4-Chloro-3-sulfamoylbenzoylthio )-2(S)-methylpropionyl ]-L-proline.
USE: A remedy for hypertension effective to essential hypertension, renal hypertension, malignant hypertension, etc.
PROCESS: The exemplified compound can be prepared e.g. by reacting 3-(4-chloro-3- sulfamoylbenzoylthio)-2(S)-methylpropionyl chloride with L-proline in the presence of sodium bicarbonate and water.
COPYRIGHT: (C)1981,JPO&Japio
JP16098779A 1979-12-11 1979-12-11 Remedy for hypertension Granted JPS5683419A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16098779A JPS5683419A (en) 1979-12-11 1979-12-11 Remedy for hypertension

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16098779A JPS5683419A (en) 1979-12-11 1979-12-11 Remedy for hypertension

Publications (2)

Publication Number Publication Date
JPS5683419A true JPS5683419A (en) 1981-07-08
JPS642568B2 JPS642568B2 (en) 1989-01-18

Family

ID=15726408

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16098779A Granted JPS5683419A (en) 1979-12-11 1979-12-11 Remedy for hypertension

Country Status (1)

Country Link
JP (1) JPS5683419A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464371A (en) * 1980-12-29 1984-08-07 Santen Pharmaceutical Co., Ltd. Five-membered heterocyclic compounds
JPH053703U (en) * 1991-07-01 1993-01-22 三菱農機株式会社 Transmission of work vehicle

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464371A (en) * 1980-12-29 1984-08-07 Santen Pharmaceutical Co., Ltd. Five-membered heterocyclic compounds
JPH053703U (en) * 1991-07-01 1993-01-22 三菱農機株式会社 Transmission of work vehicle

Also Published As

Publication number Publication date
JPS642568B2 (en) 1989-01-18

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