JPS5572179A - 1-(3-phenoxypropyl)-4-(4-alkoxybenzoyl)piperazine derivative - Google Patents

1-(3-phenoxypropyl)-4-(4-alkoxybenzoyl)piperazine derivative

Info

Publication number
JPS5572179A
JPS5572179A JP14465678A JP14465678A JPS5572179A JP S5572179 A JPS5572179 A JP S5572179A JP 14465678 A JP14465678 A JP 14465678A JP 14465678 A JP14465678 A JP 14465678A JP S5572179 A JPS5572179 A JP S5572179A
Authority
JP
Japan
Prior art keywords
phenoxypropyl
alkoxybenzoyl
compound
piperazine derivative
piperazine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP14465678A
Other languages
Japanese (ja)
Inventor
Tsutomu Irikura
Keigo Nishino
Hisaya Okamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Priority to JP14465678A priority Critical patent/JPS5572179A/en
Publication of JPS5572179A publication Critical patent/JPS5572179A/en
Pending legal-status Critical Current

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  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:1-(3-Phenoxypropyl)-4-(4-alkoxybenzoyl)piperazine derivative of formula I and its acid addition salt (R1,2 are H, methoxy, methylenedioxy, lower acyloxy, or OH; R3 is lower alkyl).
EXAMPLE: 1-(3-Phenoxypropyl)-4-(4-ethoxybenzoyl)piperazine hydrochloride.
USE: Remedy of perkinson's disease, having high activity and broad safety range. Stimulates the dopamine receptors in the central nervous system.
PROCESS: The compound I is prepared by reacting a compound II with a reactive derivative of a compound III, esp. acid chloride, or acid bromide, in a solvent such as benzene and toluene, at 0W50°C.
COPYRIGHT: (C)1980,JPO&Japio
JP14465678A 1978-11-22 1978-11-22 1-(3-phenoxypropyl)-4-(4-alkoxybenzoyl)piperazine derivative Pending JPS5572179A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14465678A JPS5572179A (en) 1978-11-22 1978-11-22 1-(3-phenoxypropyl)-4-(4-alkoxybenzoyl)piperazine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14465678A JPS5572179A (en) 1978-11-22 1978-11-22 1-(3-phenoxypropyl)-4-(4-alkoxybenzoyl)piperazine derivative

Publications (1)

Publication Number Publication Date
JPS5572179A true JPS5572179A (en) 1980-05-30

Family

ID=15367156

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14465678A Pending JPS5572179A (en) 1978-11-22 1978-11-22 1-(3-phenoxypropyl)-4-(4-alkoxybenzoyl)piperazine derivative

Country Status (1)

Country Link
JP (1) JPS5572179A (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5019858B2 (en) * 1972-01-19 1975-07-10
JPS5114160B1 (en) * 1970-09-25 1976-05-07

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5114160B1 (en) * 1970-09-25 1976-05-07
JPS5019858B2 (en) * 1972-01-19 1975-07-10

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