ES472229A1 - Un metodo de preparar un compuesto - Google Patents

Un metodo de preparar un compuesto

Info

Publication number
ES472229A1
ES472229A1 ES472229A ES472229A ES472229A1 ES 472229 A1 ES472229 A1 ES 472229A1 ES 472229 A ES472229 A ES 472229A ES 472229 A ES472229 A ES 472229A ES 472229 A1 ES472229 A1 ES 472229A1
Authority
ES
Spain
Prior art keywords
blocking agents
neuromuscular blocking
carbon atoms
image
pharmaceutically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES472229A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of ES472229A1 publication Critical patent/ES472229A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

"Un método para preparar derivados de sales de bencil- tetrahidroisoquinolinio". El presente invento proporciona nuevos y mejorados agentes de bloqueo neuromuscular llamados algunas veces relajantes musculares, que combinan un modo de acción no despolarizante con la acción de corta duración y la reversibilidad necesitada para satisfacer unos requerimientos clínicos ideales para empleo durante operaciones en cirugía. Los agentes de bloqueo neuromuscular de este invento están representados por la fórmula (I) **(Fórmula)**
ES472229A 1977-08-01 1978-07-31 Un metodo de preparar un compuesto Expired ES472229A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82079477A 1977-08-01 1977-08-01

Publications (1)

Publication Number Publication Date
ES472229A1 true ES472229A1 (es) 1979-03-16

Family

ID=25231743

Family Applications (1)

Application Number Title Priority Date Filing Date
ES472229A Expired ES472229A1 (es) 1977-08-01 1978-07-31 Un metodo de preparar un compuesto

Country Status (21)

Country Link
JP (1) JPS5455577A (es)
AT (1) AT368496B (es)
AU (1) AU523706B2 (es)
BE (1) BE869415A (es)
CA (1) CA1113096A (es)
DD (1) DD143254A5 (es)
DE (1) DE2833505A1 (es)
DK (1) DK339078A (es)
ES (1) ES472229A1 (es)
FI (1) FI782363A (es)
FR (1) FR2399429A1 (es)
GB (1) GB2002758B (es)
IE (1) IE47014B1 (es)
IL (1) IL55254A (es)
LU (1) LU80062A1 (es)
MC (1) MC1197A1 (es)
NL (1) NL7808067A (es)
PL (1) PL121492B1 (es)
SE (1) SE7808267L (es)
SU (1) SU862820A3 (es)
ZA (1) ZA784331B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235906A (en) 1978-07-21 1980-11-25 Massachusetts General Hospital Bis-isoquinolinium compounds, compositions and methods of use
CA1125287A (en) * 1978-07-21 1982-06-08 John J. Savarese Bis isoquinolinium compositions and methods of use
JPS5645459A (en) * 1979-09-20 1981-04-25 Otsuka Pharmaceut Co Ltd Cyclic amine
JPS5899465A (ja) * 1981-11-23 1983-06-13 ザ・ウエルカム・フアウンデ−シヨン・リミテツド イソキノリン誘導体
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
JPH0555438A (ja) * 1991-08-26 1993-03-05 Rohm Co Ltd 電子部品のリード端子構造
AU6730598A (en) * 1997-03-25 1998-10-20 Cornell Research Foundation Inc. Substituted isoquinolines as ultra short acting neuromuscular block ers
CN101588803B (zh) * 2006-12-06 2013-03-20 康乃尔研究基金会有限公司 中等持续时间神经肌肉阻断剂及其拮抗剂
US8592451B2 (en) 2009-03-17 2013-11-26 Cornell University Reversible nondepolarizing neuromuscular blockade agents and methods for their use
WO2011022491A1 (en) 2009-08-19 2011-02-24 Cornell University Cysteine for physiological injection
CN114057642B (zh) * 2021-12-10 2023-03-28 广东嘉博制药有限公司 一种米库氯铵中间体的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5156762U (es) * 1974-10-28 1976-05-04

Also Published As

Publication number Publication date
GB2002758A (en) 1979-02-28
FI782363A (fi) 1979-02-02
GB2002758B (en) 1982-02-03
IE781550L (en) 1979-02-01
ZA784331B (en) 1979-12-27
NL7808067A (nl) 1979-02-05
ATA555478A (de) 1982-02-15
JPS5455577A (en) 1979-05-02
MC1197A1 (fr) 1979-03-19
AU523706B2 (en) 1982-08-12
DK339078A (da) 1979-02-02
SU862820A3 (ru) 1981-09-07
IL55254A (en) 1983-03-31
FR2399429A1 (fr) 1979-03-02
AT368496B (de) 1982-10-11
PL121492B1 (en) 1982-05-31
DE2833505A1 (de) 1979-04-05
SE7808267L (sv) 1979-02-02
CA1113096A (en) 1981-11-24
FR2399429B1 (es) 1981-07-17
BE869415A (fr) 1979-01-31
IE47014B1 (en) 1983-11-30
DD143254A5 (de) 1980-08-13
PL208757A1 (pl) 1979-06-04
AU3847678A (en) 1980-02-07
IL55254A0 (en) 1978-09-29
LU80062A1 (fr) 1979-05-15

Similar Documents

Publication Publication Date Title
MY131268A (en) Novel pharmaceutically useful benzazepinyl-carbamoyl (and carboxyamido) benzoic acid derivatives and ring homologues thereof
ES454779A1 (es) Procedimiento para la obtencion de hidroxidiheterociclos eterados.
ES472229A1 (es) Un metodo de preparar un compuesto
ATE60759T1 (de) Bisdimethoxymethyl(trimethoxybenzyl)isochinolinium salze, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen.
ES452226A1 (es) Procedimiento para la preparacion de delta15-esteroides.
ES8207124A1 (es) Un procedimiento para la preparacion de derivados de aminas secundarias.
KR910007867A (ko) 페네타놀아민 화합물
PA8401801A1 (es) Agentes bloqueadores neuromusculares
ES8604991A1 (es) Un metodo para preparar peptidos farmaceuticamente activos
MY124465A (en) Reduction of infarct volume using citicoline
ES439927A1 (es) Procedimiento para la obtencion de 7-metoxi-6-tiatetracicli-nas.
GB9108629D0 (en) Heterocyclic pharmaceutical compounds,preparation and use
ES8401489A1 (es) Un procedimiento para preparar pirido (3,4-c) psoralenos o pirido (3,4-c) furo (3,2-g) curaminas.
ES468170A1 (es) Un procedimiento para la preparacion de un nuevo derivado demorfina
ES475533A1 (es) Un metodo para la preparacion de formas racemicas y optica- mente activas de 2-(4-difenilil)-n-(dimetilamino-alquil)pro-pionamida
FR2404627A1 (fr) Dichloracetamides disubstitues a l'azote, leur preparation et leur utilisation, notamment dans le traitement des amibiases
ES463424A1 (es) Procedimiento de preparacion de lactamas sustituidas en n.
UA41329C2 (uk) Фармацевтична композиція для лікування порушень серцевого ритму у великих ссавців та людей, похідні 3-фенілсульфоніл-3,7-діазабіцикло[3,3,1]нонану та лікарський засіб для лікування аритмії
ES477257A1 (es) Un procedimiento para preprarar derivados de isoquinoleina.
ES460621A1 (es) Procedimiento de sintesis de n-(1'-alil-2'-pirrolidilmetil)-2,3-dimetoxi-5-sulfamoilbenzamida.
GB2129425B (en) 5-halovinyl-2'-deoxyuridine derivatives
IL126795A0 (en) Pyridyl- and pyrimidyl-piperazines in the treatment of substance abuse disorders
EP0638064A1 (en) 1,1,2-substituted triphenylbutenes and their use in the treatment and diagnosis of cancer.
FR2457868A1 (fr) Derives de l'imidazobenzodiazepine, leur preparation et leurs utilisations therapeutiques
JPS6440425A (en) Therapeutical composition for cardiac arrhythmia

Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971103