UA41329C2 - Фармацевтична композиція для лікування порушень серцевого ритму у великих ссавців та людей, похідні 3-фенілсульфоніл-3,7-діазабіцикло[3,3,1]нонану та лікарський засіб для лікування аритмії - Google Patents
Фармацевтична композиція для лікування порушень серцевого ритму у великих ссавців та людей, похідні 3-фенілсульфоніл-3,7-діазабіцикло[3,3,1]нонану та лікарський засіб для лікування аритміїInfo
- Publication number
- UA41329C2 UA41329C2 UA95018090A UA95018090A UA41329C2 UA 41329 C2 UA41329 C2 UA 41329C2 UA 95018090 A UA95018090 A UA 95018090A UA 95018090 A UA95018090 A UA 95018090A UA 41329 C2 UA41329 C2 UA 41329C2
- Authority
- UA
- Ukraine
- Prior art keywords
- treatment
- nonan
- diazabicyclo
- derivatives
- denotes
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Цей винахід належить до застосування похідних 3,7,9,9-тетразаміщеного 3,7-діазабіцикло[3,3,1]нонану. Застосування похідних 3-фенилсульфоніл-3,7-діазабіцикло[3,3,1]нонан загальної формули (I): де R1 означає алкільну групу з 1-6 атомами вуглецю або циклоалкілалкільну групу з 4-7 атомами вуглецю, R2 означає нижчий алкіл, і R3 означає нижчий алкіл, або R2 і R3 утворюють разом алкіленовий ланцюг з 3-6 атомами вуглецю, R4 означає галоген, нітро або трифторметил, R5 означає водень або галоген, і їх фізіологічно переносимі кислотно-аддитивні солі як активний початок при отриманні фармацевтичних препаратів для лікування порушень серцевого ритму у крупніших ссавців і у людини.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4402931A DE4402931A1 (de) | 1994-02-01 | 1994-02-01 | Neue 3-Phenylsulfonyl-3,7-diazabicyclo[3,3,1] nonan-Verbindungen enthaltende Arzneimittel |
Publications (1)
Publication Number | Publication Date |
---|---|
UA41329C2 true UA41329C2 (uk) | 2001-09-17 |
Family
ID=6509146
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UA95018090A UA41329C2 (uk) | 1994-02-01 | 1995-01-31 | Фармацевтична композиція для лікування порушень серцевого ритму у великих ссавців та людей, похідні 3-фенілсульфоніл-3,7-діазабіцикло[3,3,1]нонану та лікарський засіб для лікування аритмії |
Country Status (21)
Country | Link |
---|---|
US (2) | US5576327A (uk) |
EP (1) | EP0665228B1 (uk) |
JP (2) | JP3853389B2 (uk) |
KR (1) | KR100352899B1 (uk) |
CN (1) | CN1111631A (uk) |
AT (1) | ATE182149T1 (uk) |
AU (1) | AU1156495A (uk) |
CA (1) | CA2141366A1 (uk) |
CZ (1) | CZ25395A3 (uk) |
DE (2) | DE4402931A1 (uk) |
ES (1) | ES2133593T3 (uk) |
FI (1) | FI950422A (uk) |
HU (1) | HUT70174A (uk) |
IL (1) | IL112364A (uk) |
NO (1) | NO950360L (uk) |
NZ (1) | NZ270371A (uk) |
PL (1) | PL180075B1 (uk) |
RU (1) | RU95101437A (uk) |
SK (1) | SK11795A3 (uk) |
UA (1) | UA41329C2 (uk) |
ZA (1) | ZA95697B (uk) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040229900A1 (en) * | 1999-06-16 | 2004-11-18 | Astrazeneca Ab | Bispidine compounds useful in the treatment of cardiac arrythmias |
US20050004113A1 (en) * | 1999-06-16 | 2005-01-06 | Astrazeneca Ab | New bispidine compounds useful in the treatment of cardiac arrhythmias |
SE9902270D0 (sv) | 1999-06-16 | 1999-06-16 | Astra Ab | Pharmaceutically active compounds |
SE9904765D0 (sv) | 1999-12-23 | 1999-12-23 | Astra Ab | Pharmaceutically-useful compounds |
AR030302A1 (es) * | 2000-07-07 | 2003-08-20 | Astrazeneca Ab | Compuestos de bispidina, formulacion farmaceutica, uso para la fabricacion de medicamentos, proceso para la preparacion de estos compuestos y compuestos intermediarios |
US6808924B1 (en) | 2000-07-11 | 2004-10-26 | Claudia Lanari | Mouse mammary tumor lines expressing estrogen and progesterone receptors |
SE0003795D0 (sv) | 2000-10-20 | 2000-10-20 | Astrazeneca Ab | Pharmaceutically useful compounds |
SE0100326D0 (sv) | 2001-02-02 | 2001-02-02 | Astrazeneca Ab | New compounds |
DE10131217A1 (de) | 2001-06-28 | 2003-01-09 | Solvay Pharm Gmbh | 3-Phenyl-3,7-diazabicyclo 3,3,1 nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
TW200418468A (en) * | 2002-11-18 | 2004-10-01 | Solvay Pharm Gmbh | Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3722134A1 (de) * | 1987-07-04 | 1989-01-19 | Kali Chemie Pharma Gmbh | 3-sulfonyl-3,7-diazabicyclo(3,3,1)nonan- verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
US5153214A (en) * | 1989-06-28 | 1992-10-06 | Ciba-Geigy Corporation | Certain (arylsulfonamido- and imidazolyl-)-substituted carboxylic acids and derivatives thereof and use for suppressing thromboxane activity |
US5110933A (en) * | 1989-11-13 | 1992-05-05 | Board Of Regents Of Oklahoma State University | Salts of 3-azabicyclo[3.3.1]nonanes as antiarrhythmic agents, and precursors thereof |
-
1994
- 1994-02-01 DE DE4402931A patent/DE4402931A1/de not_active Withdrawn
-
1995
- 1995-01-17 IL IL112364A patent/IL112364A/en not_active IP Right Cessation
- 1995-01-20 NZ NZ270371A patent/NZ270371A/en unknown
- 1995-01-25 AT AT95100954T patent/ATE182149T1/de not_active IP Right Cessation
- 1995-01-25 ES ES95100954T patent/ES2133593T3/es not_active Expired - Lifetime
- 1995-01-25 CN CN95101498A patent/CN1111631A/zh active Pending
- 1995-01-25 DE DE59506374T patent/DE59506374D1/de not_active Expired - Fee Related
- 1995-01-25 EP EP95100954A patent/EP0665228B1/de not_active Expired - Lifetime
- 1995-01-27 HU HU9500262A patent/HUT70174A/hu unknown
- 1995-01-28 KR KR1019950001749A patent/KR100352899B1/ko not_active IP Right Cessation
- 1995-01-30 AU AU11564/95A patent/AU1156495A/en not_active Abandoned
- 1995-01-30 CA CA002141366A patent/CA2141366A1/en not_active Abandoned
- 1995-01-30 ZA ZA95697A patent/ZA95697B/xx unknown
- 1995-01-30 PL PL95307000A patent/PL180075B1/pl not_active IP Right Cessation
- 1995-01-31 FI FI950422A patent/FI950422A/fi not_active Application Discontinuation
- 1995-01-31 RU RU95101437/04A patent/RU95101437A/ru unknown
- 1995-01-31 JP JP01420495A patent/JP3853389B2/ja not_active Expired - Fee Related
- 1995-01-31 SK SK117-95A patent/SK11795A3/sk unknown
- 1995-01-31 UA UA95018090A patent/UA41329C2/uk unknown
- 1995-01-31 NO NO950360A patent/NO950360L/no unknown
- 1995-02-01 CZ CZ95253A patent/CZ25395A3/cs unknown
- 1995-02-01 US US08/382,262 patent/US5576327A/en not_active Expired - Fee Related
-
1996
- 1996-01-31 US US08/594,946 patent/US5635511A/en not_active Expired - Lifetime
-
2005
- 2005-03-15 JP JP2005073660A patent/JP2005232179A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
PL180075B1 (pl) | 2000-12-29 |
US5576327A (en) | 1996-11-19 |
ATE182149T1 (de) | 1999-07-15 |
SK11795A3 (en) | 1995-08-09 |
ZA95697B (en) | 1996-02-07 |
EP0665228B1 (de) | 1999-07-14 |
RU95101437A (ru) | 1996-10-27 |
HU9500262D0 (en) | 1995-03-28 |
ES2133593T3 (es) | 1999-09-16 |
FI950422A (fi) | 1995-08-02 |
DE4402931A1 (de) | 1995-08-03 |
JPH07267954A (ja) | 1995-10-17 |
IL112364A (en) | 1998-01-04 |
NO950360D0 (no) | 1995-01-31 |
KR950031075A (ko) | 1995-12-18 |
FI950422A0 (fi) | 1995-01-31 |
DE59506374D1 (de) | 1999-08-19 |
MX9500679A (es) | 1998-03-31 |
CA2141366A1 (en) | 1995-08-02 |
IL112364A0 (en) | 1995-03-30 |
NZ270371A (en) | 1997-02-24 |
CN1111631A (zh) | 1995-11-15 |
JP2005232179A (ja) | 2005-09-02 |
JP3853389B2 (ja) | 2006-12-06 |
NO950360L (no) | 1995-08-02 |
AU1156495A (en) | 1995-08-10 |
CZ25395A3 (en) | 1995-10-18 |
US5635511A (en) | 1997-06-03 |
EP0665228A1 (de) | 1995-08-02 |
HUT70174A (en) | 1995-09-28 |
KR100352899B1 (ko) | 2003-02-05 |
PL307000A1 (en) | 1995-08-07 |
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