ES2109216T3 - Un procedimiento para la preparacion de una composicion farmaceutica con actividad relajante muscular de accion central. - Google Patents

Un procedimiento para la preparacion de una composicion farmaceutica con actividad relajante muscular de accion central.

Info

Publication number
ES2109216T3
ES2109216T3 ES87311455T ES87311455T ES2109216T3 ES 2109216 T3 ES2109216 T3 ES 2109216T3 ES 87311455 T ES87311455 T ES 87311455T ES 87311455 T ES87311455 T ES 87311455T ES 2109216 T3 ES2109216 T3 ES 2109216T3
Authority
ES
Spain
Prior art keywords
procedure
preparation
pharmaceutical composition
lower alkyl
muscle activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87311455T
Other languages
English (en)
Inventor
Nobuyoshi Iwata
Toshiyuki Tonohiro
Takao Hara
Mitsuo Nagano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of ES2109216T3 publication Critical patent/ES2109216T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/12—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)

Abstract

DERIVADOS DE ISOXAZOLIN-3-ONA REPRESENTADOS POR LA FORMULA GENERAL (I), EN LA QUE R1 REPRESENTA UN ATOMO DE HIDROGENO O DE HALOGENO; R2 REPRESENTA UN GRUPO ALQUILO INFERIOR O UN GRUPO HETEROCICLICO; O R1 Y R2 JUNTO CON LOS ATOMOS DE CARBONO ADYECENTES FORMAN UN ANILLO HIDROCARBONADO; R3 Y R4 REPRESENTAN UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO INFERIOR; O R3 Y R4 JUNTO CON EL ATOMO DE NITROGENO ADYACENTE PUEDEN FORMAR UN GRUPO AMINO ALICICLICO; Y SUS SALES DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLES, SON UTILES COMO RELAJENTES DE LOS MUSCULOS DE ACCION CENTRAL.
ES87311455T 1986-12-26 1987-12-24 Un procedimiento para la preparacion de una composicion farmaceutica con actividad relajante muscular de accion central. Expired - Lifetime ES2109216T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP31284386 1986-12-26

Publications (1)

Publication Number Publication Date
ES2109216T3 true ES2109216T3 (es) 1998-01-16

Family

ID=18034095

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87311455T Expired - Lifetime ES2109216T3 (es) 1986-12-26 1987-12-24 Un procedimiento para la preparacion de una composicion farmaceutica con actividad relajante muscular de accion central.

Country Status (9)

Country Link
EP (1) EP0273744B1 (es)
KR (1) KR940002821B1 (es)
AT (1) ATE55057T1 (es)
CA (1) CA1291041C (es)
DE (1) DE3764077D1 (es)
ES (1) ES2109216T3 (es)
GR (1) GR3000688T3 (es)
IE (1) IE60267B1 (es)
ZA (1) ZA879631B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5321037A (en) * 1986-12-26 1994-06-14 Sankyo Company, Limited Isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants
ATE106243T1 (de) * 1988-03-24 1994-06-15 Sankyo Co Verwendung von isoxazolinonen als cerebro-aktive medikamente.
IE62276B1 (en) * 1988-03-30 1995-01-25 Sankyo Co "New isoxazole derivatives for use as cerebro-active drugs and central muscle relaxants"
EP0367393A3 (en) * 1988-10-31 1991-03-27 Takeda Chemical Industries, Ltd. New heterocyclic compounds, production and use thereof
US5116839A (en) * 1989-06-26 1992-05-26 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
US5262413A (en) * 1989-06-26 1993-11-16 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
US5217970A (en) * 1989-06-26 1993-06-08 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
ES2060056T3 (es) * 1989-09-26 1994-11-16 Sankyo Co Derivados de 3-isoxazolonas, su preparacion y su utilizacion en terapeutica.
DK0456519T3 (da) * 1990-05-11 1994-11-07 Sankyo Co Piperidyloxy- og quinuclidinyloxyisoxazolderivater, deres fremstilling og deres terapeutiske anvendelse
EP0812318B1 (en) * 1995-02-28 2006-02-08 H. Lundbeck A/S 4-aminotetrahydrobenzisoxazole or -isothiazole compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5473775A (en) * 1977-11-21 1979-06-13 Sankyo Co Ltd Isoxazoline-3-one derivative
JPS5583766A (en) * 1978-12-18 1980-06-24 Sankyo Co Ltd Isoxazolin-3-one derivative
JPS55104274A (en) * 1979-02-05 1980-08-09 Sankyo Co Ltd Isoxazolin-3-one derivative and its preparation
JPS5634674A (en) * 1979-08-31 1981-04-06 Sankyo Co Ltd Isoxazolin-3-one derivative

Also Published As

Publication number Publication date
IE873525L (en) 1988-06-26
KR940002821B1 (ko) 1994-04-04
KR880007498A (ko) 1988-08-27
EP0273744A3 (en) 1988-10-19
DE3764077D1 (de) 1990-09-06
IE60267B1 (en) 1994-06-29
ATE55057T1 (de) 1990-08-15
CA1291041C (en) 1991-10-22
ZA879631B (en) 1989-08-30
EP0273744B1 (en) 1990-08-01
EP0273744A2 (en) 1988-07-06
GR3000688T3 (en) 1991-09-27

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