ATE106243T1 - Verwendung von isoxazolinonen als cerebro-aktive medikamente. - Google Patents
Verwendung von isoxazolinonen als cerebro-aktive medikamente.Info
- Publication number
- ATE106243T1 ATE106243T1 AT89302972T AT89302972T ATE106243T1 AT E106243 T1 ATE106243 T1 AT E106243T1 AT 89302972 T AT89302972 T AT 89302972T AT 89302972 T AT89302972 T AT 89302972T AT E106243 T1 ATE106243 T1 AT E106243T1
- Authority
- AT
- Austria
- Prior art keywords
- alkyl
- isoxazolinones
- cerebro
- hydrogen
- active medications
- Prior art date
Links
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- QXDOFVVNXBGLKK-UHFFFAOYSA-N 3-Isoxazolidinone Chemical class OC1=NOCC1 QXDOFVVNXBGLKK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003277 amino group Chemical group 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 208000026106 cerebrovascular disease Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 230000004060 metabolic process Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7042788 | 1988-03-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE106243T1 true ATE106243T1 (de) | 1994-06-15 |
Family
ID=13431170
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89302972T ATE106243T1 (de) | 1988-03-24 | 1989-03-23 | Verwendung von isoxazolinonen als cerebro-aktive medikamente. |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0334674B1 (de) |
| KR (1) | KR890014111A (de) |
| AT (1) | ATE106243T1 (de) |
| CA (1) | CA1329128C (de) |
| DE (1) | DE68915595T2 (de) |
| ES (1) | ES2057110T3 (de) |
| IE (1) | IE69021B1 (de) |
| ZA (1) | ZA892258B (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5262413A (en) * | 1989-06-26 | 1993-11-16 | Sankyo Company, Limited | Use of isoxazolin-3-one derivatives as antidepressants |
| US5217970A (en) * | 1989-06-26 | 1993-06-08 | Sankyo Company, Limited | Use of isoxazolin-3-one derivatives as antidepressants |
| US5116839A (en) * | 1989-06-26 | 1992-05-26 | Sankyo Company, Limited | Use of isoxazolin-3-one derivatives as antidepressants |
| JPH0747585B2 (ja) * | 1990-05-11 | 1995-05-24 | 三共株式会社 | イソオキサゾール誘導体 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3459862A (en) * | 1967-12-12 | 1969-08-05 | Geigy Chem Corp | Isoxazole derivatives and processes for making them |
| IT1190736B (it) * | 1982-03-15 | 1988-02-24 | Delalande Sa | Uso terapeutico di derivati noti 5-amminonetil-ossazolidin-2-one |
| JPS6183170A (ja) * | 1984-09-28 | 1986-04-26 | Nippon Chemiphar Co Ltd | 新規な1,3−オキサゾリジン−2−オン誘導体およびその製造法 |
| DE3438839A1 (de) * | 1984-10-19 | 1986-04-24 | Schering AG, 1000 Berlin und 4709 Bergkamen | Pharmazeutische praeparate |
| JPH0713017B2 (ja) * | 1986-06-18 | 1995-02-15 | 日本ケミファ株式会社 | 脳細胞保護作用を有する医薬組成物 |
| ZA879631B (en) * | 1986-12-26 | 1989-08-30 | Sankyo Co | Centrally-acting muscle relaxants |
-
1989
- 1989-03-23 AT AT89302972T patent/ATE106243T1/de not_active IP Right Cessation
- 1989-03-23 ES ES89302972T patent/ES2057110T3/es not_active Expired - Lifetime
- 1989-03-23 EP EP89302972A patent/EP0334674B1/de not_active Expired - Lifetime
- 1989-03-23 DE DE68915595T patent/DE68915595T2/de not_active Expired - Fee Related
- 1989-03-23 CA CA000594637A patent/CA1329128C/en not_active Expired - Fee Related
- 1989-03-24 KR KR1019890003749A patent/KR890014111A/ko not_active Ceased
- 1989-03-28 ZA ZA892258A patent/ZA892258B/xx unknown
- 1989-03-29 IE IE97789A patent/IE69021B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE68915595T2 (de) | 1994-09-15 |
| CA1329128C (en) | 1994-05-03 |
| IE890977L (en) | 1989-09-24 |
| EP0334674A2 (de) | 1989-09-27 |
| DE68915595D1 (de) | 1994-07-07 |
| ZA892258B (en) | 1990-12-28 |
| EP0334674A3 (en) | 1990-09-12 |
| ES2057110T3 (es) | 1994-10-16 |
| EP0334674B1 (de) | 1994-06-01 |
| IE69021B1 (en) | 1996-07-24 |
| KR890014111A (ko) | 1989-10-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |