DE68915595D1 - Verwendung von Isoxazolinonen als cerebro-aktive Medikamente. - Google Patents

Verwendung von Isoxazolinonen als cerebro-aktive Medikamente.

Info

Publication number
DE68915595D1
DE68915595D1 DE68915595T DE68915595T DE68915595D1 DE 68915595 D1 DE68915595 D1 DE 68915595D1 DE 68915595 T DE68915595 T DE 68915595T DE 68915595 T DE68915595 T DE 68915595T DE 68915595 D1 DE68915595 D1 DE 68915595D1
Authority
DE
Germany
Prior art keywords
alkyl
hydrogen
cerebroactive
isoxazolinones
drugs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68915595T
Other languages
English (en)
Other versions
DE68915595T2 (de
Inventor
Nobuyoshi Iwata
Kazuo Kobayashi
Yoshiko Kubo
Masao Kozuka
Mitsuo Nagano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Application granted granted Critical
Publication of DE68915595D1 publication Critical patent/DE68915595D1/de
Publication of DE68915595T2 publication Critical patent/DE68915595T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE68915595T 1988-03-24 1989-03-23 Verwendung von Isoxazolinonen als cerebro-aktive Medikamente. Expired - Lifetime DE68915595T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP7042788 1988-03-24

Publications (2)

Publication Number Publication Date
DE68915595D1 true DE68915595D1 (de) 1994-07-07
DE68915595T2 DE68915595T2 (de) 1994-09-15

Family

ID=13431170

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68915595T Expired - Lifetime DE68915595T2 (de) 1988-03-24 1989-03-23 Verwendung von Isoxazolinonen als cerebro-aktive Medikamente.

Country Status (8)

Country Link
EP (1) EP0334674B1 (de)
KR (1) KR890014111A (de)
AT (1) ATE106243T1 (de)
CA (1) CA1329128C (de)
DE (1) DE68915595T2 (de)
ES (1) ES2057110T3 (de)
IE (1) IE69021B1 (de)
ZA (1) ZA892258B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5262413A (en) * 1989-06-26 1993-11-16 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
US5217970A (en) * 1989-06-26 1993-06-08 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
US5116839A (en) * 1989-06-26 1992-05-26 Sankyo Company, Limited Use of isoxazolin-3-one derivatives as antidepressants
HU215832B (hu) * 1990-05-11 1999-04-28 Sankyo Co., Ltd. Eljárás piperidil-oxi- és kinuklidinil-oxi-izoxazol-származékok, és ilyen vegyületeket tartalmazó gyógyászati készítmények előállítására

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3459862A (en) * 1967-12-12 1969-08-05 Geigy Chem Corp Isoxazole derivatives and processes for making them
IT1190736B (it) * 1982-03-15 1988-02-24 Delalande Sa Uso terapeutico di derivati noti 5-amminonetil-ossazolidin-2-one
JPS6183170A (ja) * 1984-09-28 1986-04-26 Nippon Chemiphar Co Ltd 新規な１，３−オキサゾリジン−２−オン誘導体およびその製造法
DE3438839A1 (de) * 1984-10-19 1986-04-24 Schering AG, 1000 Berlin und 4709 Bergkamen Pharmazeutische praeparate
JPH0713017B2 (ja) * 1986-06-18 1995-02-15 日本ケミファ株式会社 脳細胞保護作用を有する医薬組成物
ZA879631B (en) * 1986-12-26 1989-08-30 Sankyo Co Centrally-acting muscle relaxants

Also Published As

Publication number Publication date
CA1329128C (en) 1994-05-03
ATE106243T1 (de) 1994-06-15
DE68915595T2 (de) 1994-09-15
ZA892258B (en) 1990-12-28
ES2057110T3 (es) 1994-10-16
EP0334674B1 (de) 1994-06-01
EP0334674A2 (de) 1989-09-27
KR890014111A (ko) 1989-10-21
IE890977L (en) 1989-09-24
IE69021B1 (en) 1996-07-24
EP0334674A3 (en) 1990-09-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee