ATE71090T1 - Heterocyclische verbindungen und deren herstellung und verwendung. - Google Patents

Heterocyclische verbindungen und deren herstellung und verwendung.

Info

Publication number
ATE71090T1
ATE71090T1 AT88104379T AT88104379T ATE71090T1 AT E71090 T1 ATE71090 T1 AT E71090T1 AT 88104379 T AT88104379 T AT 88104379T AT 88104379 T AT88104379 T AT 88104379T AT E71090 T1 ATE71090 T1 AT E71090T1
Authority
AT
Austria
Prior art keywords
compounds
preparation
heterocyclic compounds
chem
so2nh2
Prior art date
Application number
AT88104379T
Other languages
English (en)
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Tage Honore
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE71090T1 publication Critical patent/ATE71090T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT88104379T 1987-03-23 1988-03-18 Heterocyclische verbindungen und deren herstellung und verwendung. ATE71090T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK146787A DK146787A (da) 1987-03-23 1987-03-23 Heterocykliske forbindelser, deres fremstilling og anvendelse
EP88104379A EP0283959B1 (de) 1987-03-23 1988-03-18 Heterocyclische Verbindungen und deren Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ATE71090T1 true ATE71090T1 (de) 1992-01-15

Family

ID=8105140

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88104379T ATE71090T1 (de) 1987-03-23 1988-03-18 Heterocyclische verbindungen und deren herstellung und verwendung.

Country Status (18)

Country Link
US (2) US4889855A (de)
EP (1) EP0283959B1 (de)
KR (1) KR960003324B1 (de)
AT (1) ATE71090T1 (de)
AU (1) AU596737B2 (de)
CA (1) CA1315789C (de)
DE (1) DE3867268D1 (de)
DK (1) DK146787A (de)
ES (1) ES2037753T3 (de)
FI (1) FI92582C (de)
GR (1) GR3003910T3 (de)
IE (1) IE60002B1 (de)
IL (1) IL85328A (de)
NO (1) NO174549C (de)
NZ (1) NZ223776A (de)
PH (1) PH23979A (de)
PT (1) PT87063B (de)
ZA (1) ZA881139B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
US5308845A (en) * 1988-12-22 1994-05-03 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
PT99864B (pt) * 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
DK73091D0 (da) * 1991-04-22 1991-04-22 Novo Nordisk As Quinoxalinforbindelser, deres fremstilling og anvendelse
AU660717B2 (en) * 1991-09-09 1995-07-06 Warner-Lambert Company Pharmaceutical preparation containing an uricosuric and an excitatory amino acid antagonist
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
PT647137E (pt) * 1992-06-22 2008-11-24 Univ California Antagonistas dos receptores da glicina e a sua utilização
JPH08502483A (ja) 1992-10-13 1996-03-19 ワーナー−ランバート・コンパニー 新規なキノキサリンジオン誘導体、それらの製造および使用
DK12293D0 (da) * 1993-02-02 1993-02-02 Novo Nordisk As Heterocykliske forbindelser og deres fremstilling og anvendelse
FI954965L (fi) * 1993-05-13 1995-11-10 Neurosearch As AMPA-antagonisteja ja hoitomenetelmä, jossa niitä käytetään
US5843945A (en) * 1993-05-13 1998-12-01 Neurosearch A/S AMPA antagonists and a method of treatment
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
GB9419318D0 (en) * 1994-09-24 1994-11-09 Pfizer Ltd Therapeutic agents
DE4436852A1 (de) * 1994-10-14 1996-04-18 Basf Ag Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
WO1996017832A1 (en) * 1994-12-07 1996-06-13 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkylquinoxalinediones
US5721234A (en) * 1994-12-07 1998-02-24 Warner-Lambert Company Glutamate receptor antagonists: fused cycloalkylouinoxalinediones
JPH11501619A (ja) * 1995-02-15 1999-02-09 ベアーズデン バイオ，インコーポレイテッド アルキルカルボキシアミノ酸−カイネートレセプターのモジュレーター
WO1996028445A1 (en) 1995-03-14 1996-09-19 Warner-Lambert Company Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones
US5719153A (en) * 1995-08-15 1998-02-17 American Home Products Corporation 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
WO1998005651A1 (en) * 1996-08-01 1998-02-12 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkyl quinoxalinediones
FR2752163B1 (fr) * 1996-08-12 1998-10-30 Pf Medicament Utilisation de l'efaroxan pour la fabricaton de medicament destine au traitement de la maladie de huntington
US5968928A (en) * 1996-09-19 1999-10-19 Warner-Lambert Company Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof
EP3427729A1 (de) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen
US20240398775A1 (en) 2021-09-15 2024-12-05 University Of The Ryukyus Pharmaceutical composition for use in treating cognitive decline or for use in treating overweight or obesity
EP4403185A4 (de) 2021-09-15 2025-10-08 Univ Of The Ryukyus Pharmazeutische zusammensetzung zur behandlung von kognitivem verfall oder zur behandlung von übergewicht oder adipositas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431111A (en) * 1963-06-10 1969-03-04 Eastman Kodak Co Cyanine dyes
US3772273A (en) * 1969-01-17 1973-11-13 Allied Chem Derivatives of quinoxaline
US3962440A (en) * 1973-12-26 1976-06-08 Eli Lilly And Company Quinoxaline compounds as hypnotic agents
US4430502A (en) * 1982-08-13 1984-02-07 The Upjohn Company Pyridinyl substituted benzimidazoles and quinoxalines
FR2583751B1 (fr) * 1985-06-20 1989-10-13 Panmedica Nouveaux antibacteriens contenant des derives des acides oxo-4-pyridine carboxyliques et leur procede de preparation

Also Published As

Publication number Publication date
DK146787D0 (da) 1987-03-23
NZ223776A (en) 1990-10-26
NO881264D0 (no) 1988-03-22
IL85328A (en) 1993-06-10
FI880816A0 (fi) 1988-02-22
PH23979A (en) 1990-02-09
KR960003324B1 (ko) 1996-03-08
US4912108A (en) 1990-03-27
FI92582B (fi) 1994-08-31
NO881264L (no) 1988-09-26
DK146787A (da) 1988-09-24
AU596737B2 (en) 1990-05-10
FI880816A7 (fi) 1988-09-24
DE3867268D1 (de) 1992-02-13
PT87063B (pt) 1992-07-31
NO174549C (no) 1994-05-25
EP0283959B1 (de) 1992-01-02
ZA881139B (en) 1988-08-15
AU1326088A (en) 1988-09-22
GR3003910T3 (de) 1993-03-16
PT87063A (pt) 1988-04-01
KR880011125A (ko) 1988-10-26
IE60002B1 (en) 1994-05-18
NO174549B (no) 1994-02-14
EP0283959A1 (de) 1988-09-28
IE880439L (en) 1988-09-23
CA1315789C (en) 1993-04-06
FI92582C (fi) 1994-12-12
ES2037753T3 (es) 1993-07-01
US4889855A (en) 1989-12-26

Similar Documents

Publication Publication Date Title
ATE71090T1 (de) Heterocyclische verbindungen und deren herstellung und verwendung.
ATE90092T1 (de) Thiazolidinon-derivate, ihre herstellung und ihre verwendung.
DE68920654D1 (de) 4-Oxochinolin-3-carbonsäure-Derivate, ihre Herstellung und ihre Verwendung.
DE69112989D1 (de) Aminocoumaranderivate, ihre Herstellung und Verwendung.
FI913478A0 (fi) Diazinderivat.
DE3678469D1 (de) Aminosaeure-derivate und ihre anwendung zur herstellung eines antikrampfmittels.
ATE92489T1 (de) Imid-derivate, ihre herstellung und verwendung.
NO873873D0 (no) Kinoxalinforbindelser samt fremgangsmaate for fremstilling derav.
DE69018726D1 (de) Cumarinderivate, ihre Herstellung und ihre Verwendung zur Behandlung von zerebrovaskulären Störungen.
ATE58532T1 (de) (2-amino-4-aryl-thiazol-5-yl)aethanol, und deren derivate mit diuretischer aktivitaet und verfahren zu deren herstellung.
DK384485A (da) 1,6-naphthyridinderivater med kardilaterende virkning
HU903266D0 (en) Process for producing amine-derivatives and pharmaceutical preparatives containing these compounds as active substance
DE3787844D1 (de) Thioester und dessen Verwendung zur Herstellung von pharmazeutischen Zusammensetzungen zur Behandlung von Ischämie und von Reperfusion-Syndromen.
ATE88176T1 (de) 2-hydroxy-3-aryloxy-propylaminderivate mit kardiovaskulaerer wirkung.
MA20369A1 (fr) Compositions a base de derives de la piperidine ,nouveaux derives de la piperidine et leurs procedes de preparation
DE68915595D1 (de) Verwendung von Isoxazolinonen als cerebro-aktive Medikamente.
KR950017956A (ko) N-치환 아자비시클로헵탄 유도체, 그의 제조 방법 및 용도

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee