FI92582B - Menetelmä uusien terapeuttisesti käyttökelpoisten kinoksaliinijohdannaisten valmistamiseksi - Google Patents

Menetelmä uusien terapeuttisesti käyttökelpoisten kinoksaliinijohdannaisten valmistamiseksi

Info

Publication number
FI92582B
FI92582B FI880816A FI880816A FI92582B FI 92582 B FI92582 B FI 92582B FI 880816 A FI880816 A FI 880816A FI 880816 A FI880816 A FI 880816A FI 92582 B FI92582 B FI 92582B
Authority
FI
Finland
Prior art keywords
preparation
therapeutically useful
quinoxaline derivatives
new therapeutically
compounds
Prior art date
Application number
FI880816A
Other languages
English (en)
Swedish (sv)
Other versions
FI880816A0 (fi
FI880816A (fi
FI92582C (fi
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Tage Honore
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI880816A0 publication Critical patent/FI880816A0/fi
Publication of FI880816A publication Critical patent/FI880816A/fi
Publication of FI92582B publication Critical patent/FI92582B/fi
Application granted granted Critical
Publication of FI92582C publication Critical patent/FI92582C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyrrole Compounds (AREA)
FI880816A 1987-03-23 1988-02-22 Menetelmä uusien terapeuttisesti käyttökelpoisten kinoksaliinijohdannaisten valmistamiseksi FI92582C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK146787A DK146787A (da) 1987-03-23 1987-03-23 Heterocykliske forbindelser, deres fremstilling og anvendelse
DK146787 1987-03-23

Publications (4)

Publication Number Publication Date
FI880816A0 FI880816A0 (fi) 1988-02-22
FI880816A FI880816A (fi) 1988-09-24
FI92582B true FI92582B (fi) 1994-08-31
FI92582C FI92582C (fi) 1994-12-12

Family

ID=8105140

Family Applications (1)

Application Number Title Priority Date Filing Date
FI880816A FI92582C (fi) 1987-03-23 1988-02-22 Menetelmä uusien terapeuttisesti käyttökelpoisten kinoksaliinijohdannaisten valmistamiseksi

Country Status (18)

Country Link
US (2) US4889855A (fi)
EP (1) EP0283959B1 (fi)
KR (1) KR960003324B1 (fi)
AT (1) ATE71090T1 (fi)
AU (1) AU596737B2 (fi)
CA (1) CA1315789C (fi)
DE (1) DE3867268D1 (fi)
DK (1) DK146787A (fi)
ES (1) ES2037753T3 (fi)
FI (1) FI92582C (fi)
GR (1) GR3003910T3 (fi)
IE (1) IE60002B1 (fi)
IL (1) IL85328A (fi)
NO (1) NO174549C (fi)
NZ (1) NZ223776A (fi)
PH (1) PH23979A (fi)
PT (1) PT87063B (fi)
ZA (1) ZA881139B (fi)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
US5308845A (en) * 1988-12-22 1994-05-03 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
PT99864B (pt) * 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
DK73091D0 (da) * 1991-04-22 1991-04-22 Novo Nordisk As Quinoxalinforbindelser, deres fremstilling og anvendelse
WO1993004688A1 (en) * 1991-09-09 1993-03-18 Warner-Lambert Company Pharmaceutical preparation containing an uricosuric and an excitatory amino acid antagonist
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
WO1994000124A1 (en) * 1992-06-22 1994-01-06 Eckard Weber Glycine receptor antagonists and the use thereof
EP0664807B1 (en) 1992-10-13 1997-09-10 Warner-Lambert Company Quinoxalinedione derivatives as eaa antagonists
DK12293D0 (da) * 1993-02-02 1993-02-02 Novo Nordisk As Heterocykliske forbindelser og deres fremstilling og anvendelse
JP3439215B2 (ja) * 1993-05-13 2003-08-25 ノイロサーチ アクティーゼルスカブ Ａｍｐａ拮抗薬およびそれを用いての治療方法
US5843945A (en) * 1993-05-13 1998-12-01 Neurosearch A/S AMPA antagonists and a method of treatment
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
GB9419318D0 (en) * 1994-09-24 1994-11-09 Pfizer Ltd Therapeutic agents
DE4436852A1 (de) * 1994-10-14 1996-04-18 Basf Ag Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
US5721234A (en) * 1994-12-07 1998-02-24 Warner-Lambert Company Glutamate receptor antagonists: fused cycloalkylouinoxalinediones
WO1996017832A1 (en) * 1994-12-07 1996-06-13 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkylquinoxalinediones
US5731348A (en) * 1995-02-15 1998-03-24 Bearsden Bio, Inc. Alkylcarboxy amino acids-modulators of the kainate receptor
AU4423496A (en) 1995-03-14 1996-10-02 Warner-Lambert Company Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones
US5719153A (en) * 1995-08-15 1998-02-17 American Home Products Corporation 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
WO1998005651A1 (en) * 1996-08-01 1998-02-12 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkyl quinoxalinediones
FR2752163B1 (fr) * 1996-08-12 1998-10-30 Pf Medicament Utilisation de l'efaroxan pour la fabricaton de medicament destine au traitement de la maladie de huntington
US5968928A (en) * 1996-09-19 1999-10-19 Warner-Lambert Company Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof
EP3427729A1 (en) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid for use in treating epileptic diseases, disorders or conditions
WO2023042888A1 (ja) 2021-09-15 2023-03-23 国立大学法人 琉球大学 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物
WO2023042887A1 (ja) 2021-09-15 2023-03-23 国立大学法人 琉球大学 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431111A (en) * 1963-06-10 1969-03-04 Eastman Kodak Co Cyanine dyes
US3772273A (en) * 1969-01-17 1973-11-13 Allied Chem Derivatives of quinoxaline
US3962440A (en) * 1973-12-26 1976-06-08 Eli Lilly And Company Quinoxaline compounds as hypnotic agents
US4430502A (en) * 1982-08-13 1984-02-07 The Upjohn Company Pyridinyl substituted benzimidazoles and quinoxalines
FR2583751B1 (fr) * 1985-06-20 1989-10-13 Panmedica Nouveaux antibacteriens contenant des derives des acides oxo-4-pyridine carboxyliques et leur procede de preparation

Also Published As

Publication number Publication date
US4889855A (en) 1989-12-26
IE60002B1 (en) 1994-05-18
CA1315789C (en) 1993-04-06
NO881264D0 (no) 1988-03-22
FI880816A0 (fi) 1988-02-22
DK146787A (da) 1988-09-24
NO174549C (no) 1994-05-25
AU1326088A (en) 1988-09-22
NO174549B (no) 1994-02-14
FI880816A (fi) 1988-09-24
KR960003324B1 (ko) 1996-03-08
US4912108A (en) 1990-03-27
PT87063B (pt) 1992-07-31
KR880011125A (ko) 1988-10-26
PT87063A (pt) 1988-04-01
ZA881139B (en) 1988-08-15
ATE71090T1 (de) 1992-01-15
DE3867268D1 (de) 1992-02-13
NO881264L (no) 1988-09-26
EP0283959A1 (en) 1988-09-28
GR3003910T3 (fi) 1993-03-16
IE880439L (en) 1988-09-23
PH23979A (en) 1990-02-09
IL85328A (en) 1993-06-10
FI92582C (fi) 1994-12-12
ES2037753T3 (es) 1993-07-01
AU596737B2 (en) 1990-05-10
DK146787D0 (da) 1987-03-23
NZ223776A (en) 1990-10-26
EP0283959B1 (en) 1992-01-02

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FI92582B (fi) Menetelmä uusien terapeuttisesti käyttökelpoisten kinoksaliinijohdannaisten valmistamiseksi
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ES2058285T3 (es) Procedimiento para la preparacion de derivados de indolinona sustituida.
DK0430201T3 (fi)
NO173499C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinoxalinforbindelser
HU903266D0 (en) Process for producing amine-derivatives and pharmaceutical preparatives containing these compounds as active substance
DK142188A (da) Heterocykliske forbindelser, deres fremstilling og anvendelse

Legal Events

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BB Publication of examined application
MM Patent lapsed

Owner name: NOVO NORDISK A/S