NO174549C - Analogifremgangsmåte for fremstilling av terapeutisk aktive, asymmetrisk substituerte, heterocykliske forbindelser - Google Patents

Analogifremgangsmåte for fremstilling av terapeutisk aktive, asymmetrisk substituerte, heterocykliske forbindelser

Info

Publication number
NO174549C
NO174549C NO881264A NO881264A NO174549C NO 174549 C NO174549 C NO 174549C NO 881264 A NO881264 A NO 881264A NO 881264 A NO881264 A NO 881264A NO 174549 C NO174549 C NO 174549C
Authority
NO
Norway
Prior art keywords
substituted heterocyclic
therapeutically active
heterocyclic compounds
asymmetrically substituted
analogous process
Prior art date
Application number
NO881264A
Other languages
English (en)
Norwegian (no)
Other versions
NO174549B (no
NO881264D0 (no
NO881264L (no
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Tage Honore
Original Assignee
Novo Nordisk As
Ferrosan As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As, Ferrosan As filed Critical Novo Nordisk As
Publication of NO881264D0 publication Critical patent/NO881264D0/no
Publication of NO881264L publication Critical patent/NO881264L/no
Publication of NO174549B publication Critical patent/NO174549B/no
Publication of NO174549C publication Critical patent/NO174549C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40—Benzopyrazines
    • C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO881264A 1987-03-23 1988-03-22 Analogifremgangsmåte for fremstilling av terapeutisk aktive, asymmetrisk substituerte, heterocykliske forbindelser NO174549C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK146787A DK146787A (da) 1987-03-23 1987-03-23 Heterocykliske forbindelser, deres fremstilling og anvendelse

Publications (4)

Publication Number Publication Date
NO881264D0 NO881264D0 (no) 1988-03-22
NO881264L NO881264L (no) 1988-09-26
NO174549B NO174549B (no) 1994-02-14
NO174549C true NO174549C (no) 1994-05-25

Family

ID=8105140

Family Applications (1)

Application Number Title Priority Date Filing Date
NO881264A NO174549C (no) 1987-03-23 1988-03-22 Analogifremgangsmåte for fremstilling av terapeutisk aktive, asymmetrisk substituerte, heterocykliske forbindelser

Country Status (18)

Country Link
US (2) US4889855A (de)
EP (1) EP0283959B1 (de)
KR (1) KR960003324B1 (de)
AT (1) ATE71090T1 (de)
AU (1) AU596737B2 (de)
CA (1) CA1315789C (de)
DE (1) DE3867268D1 (de)
DK (1) DK146787A (de)
ES (1) ES2037753T3 (de)
FI (1) FI92582C (de)
GR (1) GR3003910T3 (de)
IE (1) IE60002B1 (de)
IL (1) IL85328A (de)
NO (1) NO174549C (de)
NZ (1) NZ223776A (de)
PH (1) PH23979A (de)
PT (1) PT87063B (de)
ZA (1) ZA881139B (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4743607A (en) * 1987-05-29 1988-05-10 Merrell Dow Pharmaceuticals Inc. Cardiotonic tricyclic imidazolones
NO179551C (no) * 1987-11-10 1996-10-30 Novo Nordisk As Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser
DK160941C (da) * 1988-06-28 1991-10-21 Novo Nordisk As Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar
DK716188D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
DK715888D0 (da) * 1988-12-22 1988-12-22 Ferrosan As Quinoxalinforbindelser, deres fremstilling og anvendelse
US5308845A (en) * 1988-12-22 1994-05-03 Novo Nordisk A/S Quinoxaline compounds and their preparation and use
PT99864B (pt) * 1990-12-21 1999-06-30 Schering Ag Processo para a preparacao de novas composicoes farmaceuticas contendo antagonistas de receptor de quisqualato
DK73091D0 (da) * 1991-04-22 1991-04-22 Novo Nordisk As Quinoxalinforbindelser, deres fremstilling og anvendelse
EP0603301B1 (de) * 1991-09-09 1998-01-14 Warner-Lambert Company Pharmazeutisches kombinationspräparat, das ein uricosurisches mittel und einen excitatorischen aminosäure-antagonisten enthält
DE4217952A1 (de) * 1992-05-30 1993-12-02 Basf Ag Chinoxalin-2,3(1H,4H)-dione
ATE404201T1 (de) * 1992-06-22 2008-08-15 Univ California Glycinrezeptorantagonisten und ihre verwendung
EP0664807B1 (de) * 1992-10-13 1997-09-10 Warner-Lambert Company Chinoxalinderivate als eaa antagonisten
DK12293D0 (da) * 1993-02-02 1993-02-02 Novo Nordisk As Heterocykliske forbindelser og deres fremstilling og anvendelse
US5843945A (en) * 1993-05-13 1998-12-01 Neurosearch A/S AMPA antagonists and a method of treatment
AU679075B2 (en) * 1993-05-13 1997-06-19 Neurosearch A/S Ampa antagonists and a method of treatment therewith
US5631373A (en) * 1993-11-05 1997-05-20 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones
GB9419318D0 (en) * 1994-09-24 1994-11-09 Pfizer Ltd Therapeutic agents
DE4436852A1 (de) * 1994-10-14 1996-04-18 Basf Ag Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung
US5721234A (en) * 1994-12-07 1998-02-24 Warner-Lambert Company Glutamate receptor antagonists: fused cycloalkylouinoxalinediones
WO1996017832A1 (en) * 1994-12-07 1996-06-13 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkylquinoxalinediones
US5731348A (en) * 1995-02-15 1998-03-24 Bearsden Bio, Inc. Alkylcarboxy amino acids-modulators of the kainate receptor
WO1996028445A1 (en) * 1995-03-14 1996-09-19 Warner-Lambert Company Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones
US5719153A (en) * 1995-08-15 1998-02-17 American Home Products Corporation 5H,8H-2-oxa-1,3,5,8-tetraaza-cyclopenta b!-naphthalene-6,7-diones
AU3571997A (en) * 1996-08-01 1998-02-25 Warner-Lambert Company Novel glutamate receptor antagonists: fused cycloalkyl quinoxalinediones
FR2752163B1 (fr) * 1996-08-12 1998-10-30 Pf Medicament Utilisation de l'efaroxan pour la fabricaton de medicament destine au traitement de la maladie de huntington
US5968928A (en) * 1996-09-19 1999-10-19 Warner-Lambert Company Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof
EP3427729A1 (de) 2017-07-13 2019-01-16 Paris Sciences et Lettres - Quartier Latin Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen
WO2023042888A1 (ja) 2021-09-15 2023-03-23 国立大学法人 琉球大学 認知機能低下、または過体重もしくは肥満症を処置することに用いるための医薬組成物
EP4403184A1 (de) 2021-09-15 2024-07-24 University of The Ryukyus Pharmazeutische zusammensetzung zur verwendung bei der behandlung von kognitivem verfall, übergewicht oder adipositas

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3431111A (en) * 1963-06-10 1969-03-04 Eastman Kodak Co Cyanine dyes
US3772273A (en) * 1969-01-17 1973-11-13 Allied Chem Derivatives of quinoxaline
US3962440A (en) * 1973-12-26 1976-06-08 Eli Lilly And Company Quinoxaline compounds as hypnotic agents
US4430502A (en) * 1982-08-13 1984-02-07 The Upjohn Company Pyridinyl substituted benzimidazoles and quinoxalines
FR2583751B1 (fr) * 1985-06-20 1989-10-13 Panmedica Nouveaux antibacteriens contenant des derives des acides oxo-4-pyridine carboxyliques et leur procede de preparation

Also Published As

Publication number Publication date
ATE71090T1 (de) 1992-01-15
US4912108A (en) 1990-03-27
EP0283959A1 (de) 1988-09-28
DK146787D0 (da) 1987-03-23
FI880816A0 (fi) 1988-02-22
DE3867268D1 (de) 1992-02-13
AU1326088A (en) 1988-09-22
IL85328A (en) 1993-06-10
EP0283959B1 (de) 1992-01-02
FI880816A (fi) 1988-09-24
PT87063A (pt) 1988-04-01
GR3003910T3 (de) 1993-03-16
US4889855A (en) 1989-12-26
NO174549B (no) 1994-02-14
NO881264D0 (no) 1988-03-22
ES2037753T3 (es) 1993-07-01
PH23979A (en) 1990-02-09
ZA881139B (en) 1988-08-15
CA1315789C (en) 1993-04-06
AU596737B2 (en) 1990-05-10
IE880439L (en) 1988-09-23
IE60002B1 (en) 1994-05-18
FI92582C (fi) 1994-12-12
PT87063B (pt) 1992-07-31
NZ223776A (en) 1990-10-26
DK146787A (da) 1988-09-24
KR880011125A (ko) 1988-10-26
NO881264L (no) 1988-09-26
KR960003324B1 (ko) 1996-03-08
FI92582B (fi) 1994-08-31

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