ATE137759T1 - S'-adenosyl-methionin-decarboxylase-inhibitoren - Google Patents
S'-adenosyl-methionin-decarboxylase-inhibitorenInfo
- Publication number
- ATE137759T1 ATE137759T1 AT89401845T AT89401845T ATE137759T1 AT E137759 T1 ATE137759 T1 AT E137759T1 AT 89401845 T AT89401845 T AT 89401845T AT 89401845 T AT89401845 T AT 89401845T AT E137759 T1 ATE137759 T1 AT E137759T1
- Authority
- AT
- Austria
- Prior art keywords
- chem
- decarboxylase inhibitors
- adenosyl
- methionine decarboxylase
- adenosinyl
- Prior art date
Links
- 239000003954 decarboxylase inhibitor Substances 0.000 title abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 102000005758 Adenosylmethionine decarboxylase Human genes 0.000 abstract 1
- 108010070753 Adenosylmethionine decarboxylase Proteins 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000896 monocarboxylic acid group Chemical group 0.000 abstract 1
- 230000035755 proliferation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Pyridine Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP88401896A EP0351475A1 (de) | 1988-07-21 | 1988-07-21 | S-Adenosylmethionin-decarboxylase-Inhibitoren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE137759T1 true ATE137759T1 (de) | 1996-05-15 |
Family
ID=8200409
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89401845T ATE137759T1 (de) | 1988-07-21 | 1989-06-28 | S'-adenosyl-methionin-decarboxylase-inhibitoren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5416076A (de) |
| EP (1) | EP0351475A1 (de) |
| AT (1) | ATE137759T1 (de) |
| DE (1) | DE68926418T2 (de) |
| ES (1) | ES2088903T3 (de) |
| GR (1) | GR3019893T3 (de) |
| HU (1) | HU204536B (de) |
| ZA (1) | ZA895387B (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA916464B (en) * | 1990-08-22 | 1992-05-27 | Merrell Dow Pharma | 5'-amine substituted adenosine analogs as immunosuppressants |
| US5308837A (en) * | 1990-08-22 | 1994-05-03 | Merrell Dow Pharmaceuticals Inc. | 5'-amine substituted adenosine analogs as immunosuppressants |
| US5750496A (en) * | 1996-08-12 | 1998-05-12 | Utah State University | Method of controlling cryptosporidium infectons using protease inhibitors |
| US5733889A (en) * | 1996-10-29 | 1998-03-31 | The Metrohealth System | Treatment for cardiac arrhythmias |
| US6534651B2 (en) * | 2000-04-06 | 2003-03-18 | Inotek Pharmaceuticals Corp. | 7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof |
| US20030224970A1 (en) * | 2002-05-17 | 2003-12-04 | Sanjoy Mahanty | Methods for the identification of inhibitors of S-adenosylmethionine decarboxylase as antibiotics |
| EP1834669A1 (de) * | 2006-03-15 | 2007-09-19 | Heinrich-Pette-Institut | Verwendung von Hydrazonverbindungen zur Behandlung viraler Infektionen |
| US8633168B2 (en) * | 2007-06-15 | 2014-01-21 | Genzyme Corporation | Inhibitors of S-adenosyl-L-methionine decarboxylase |
| US8637485B2 (en) * | 2007-08-02 | 2014-01-28 | Southern Research Institute | 5′,-substituted adenosynes preparation thereof and use as inhibitors of S-adenosylmethionine decarboxylase |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4134918A (en) * | 1977-09-06 | 1979-01-16 | Merrell Toraude Et Compagnie | Alpha-halomethyl derivatives of amines |
| US4794174A (en) * | 1987-02-10 | 1988-12-27 | Southern Research Institute | 5'deoxy-5'-substituted adenosines |
-
1988
- 1988-07-21 EP EP88401896A patent/EP0351475A1/de not_active Withdrawn
-
1989
- 1989-06-28 AT AT89401845T patent/ATE137759T1/de not_active IP Right Cessation
- 1989-06-28 ES ES89401845T patent/ES2088903T3/es not_active Expired - Lifetime
- 1989-06-28 DE DE68926418T patent/DE68926418T2/de not_active Expired - Lifetime
- 1989-07-14 ZA ZA895387A patent/ZA895387B/xx unknown
- 1989-07-20 HU HU893694A patent/HU204536B/hu not_active IP Right Cessation
-
1992
- 1992-06-09 US US07/896,733 patent/US5416076A/en not_active Expired - Lifetime
-
1996
- 1996-05-13 GR GR960401274T patent/GR3019893T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GR3019893T3 (en) | 1996-08-31 |
| ES2088903T3 (es) | 1996-10-01 |
| DE68926418T2 (de) | 1996-09-19 |
| HUT50354A (en) | 1990-01-29 |
| EP0351475A1 (de) | 1990-01-24 |
| HU204536B (en) | 1992-01-28 |
| DE68926418D1 (de) | 1996-06-13 |
| US5416076A (en) | 1995-05-16 |
| ZA895387B (en) | 1990-04-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |