MC1197A1 - Composes tetrahydro-isoquinoleiniques myorelaxants(agents de blocage de la plaque neuro-musculaire)et leur preparation - Google Patents

Composes tetrahydro-isoquinoleiniques myorelaxants(agents de blocage de la plaque neuro-musculaire)et leur preparation

Info

Publication number
MC1197A1
MC1197A1 MC781316A MC1316A MC1197A1 MC 1197 A1 MC1197 A1 MC 1197A1 MC 781316 A MC781316 A MC 781316A MC 1316 A MC1316 A MC 1316A MC 1197 A1 MC1197 A1 MC 1197A1
Authority
MC
Monaco
Prior art keywords
isoquinoleinic
myorelaxant
tetrahydro
compounds
preparation
Prior art date
Application number
MC781316A
Other languages
English (en)
Inventor
R Kitz
J Savarese
S Ginsburg
Original Assignee
Massachusetts Gen Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Gen Hospital filed Critical Massachusetts Gen Hospital
Publication of MC1197A1 publication Critical patent/MC1197A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
MC781316A 1977-08-01 1978-07-31 Composes tetrahydro-isoquinoleiniques myorelaxants(agents de blocage de la plaque neuro-musculaire)et leur preparation MC1197A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82079477A 1977-08-01 1977-08-01

Publications (1)

Publication Number Publication Date
MC1197A1 true MC1197A1 (fr) 1979-03-19

Family

ID=25231743

Family Applications (1)

Application Number Title Priority Date Filing Date
MC781316A MC1197A1 (fr) 1977-08-01 1978-07-31 Composes tetrahydro-isoquinoleiniques myorelaxants(agents de blocage de la plaque neuro-musculaire)et leur preparation

Country Status (21)

Country Link
JP (1) JPS5455577A (fr)
AT (1) AT368496B (fr)
AU (1) AU523706B2 (fr)
BE (1) BE869415A (fr)
CA (1) CA1113096A (fr)
DD (1) DD143254A5 (fr)
DE (1) DE2833505A1 (fr)
DK (1) DK339078A (fr)
ES (1) ES472229A1 (fr)
FI (1) FI782363A (fr)
FR (1) FR2399429A1 (fr)
GB (1) GB2002758B (fr)
IE (1) IE47014B1 (fr)
IL (1) IL55254A (fr)
LU (1) LU80062A1 (fr)
MC (1) MC1197A1 (fr)
NL (1) NL7808067A (fr)
PL (1) PL121492B1 (fr)
SE (1) SE7808267L (fr)
SU (1) SU862820A3 (fr)
ZA (1) ZA784331B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235906A (en) 1978-07-21 1980-11-25 Massachusetts General Hospital Bis-isoquinolinium compounds, compositions and methods of use
CA1125287A (fr) * 1978-07-21 1982-06-08 John J. Savarese Modes d'emploi de substances a base de bis-isoquinolinium
JPS5645459A (en) * 1979-09-20 1981-04-25 Otsuka Pharmaceut Co Ltd Cyclic amine
JPS5899465A (ja) * 1981-11-23 1983-06-13 ザ・ウエルカム・フアウンデ−シヨン・リミテツド イソキノリン誘導体
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
JPH0555438A (ja) * 1991-08-26 1993-03-05 Rohm Co Ltd 電子部品のリード端子構造
CA2284802C (fr) * 1997-03-25 2009-06-16 Cornell Research Foundation, Inc. Isoquinoleines substituees en tant qu'inhibiteurs neuromusculaires exercant une action extremement courte
US8148398B2 (en) * 2006-12-06 2012-04-03 Cornell Research Foundation, Inc. Intermediate duration neuromuscular blocking agents and antagonists thereof
WO2010107488A1 (fr) 2009-03-17 2010-09-23 Cornell University Agents de blocage neuromusculaires non dépolarisants réversibles et leur méthode
US9220700B2 (en) 2009-08-19 2015-12-29 Cornell University Cysteine for physiological injection
CN114057642B (zh) * 2021-12-10 2023-03-28 广东嘉博制药有限公司 一种米库氯铵中间体的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5156762U (fr) * 1974-10-28 1976-05-04

Also Published As

Publication number Publication date
SE7808267L (sv) 1979-02-02
JPS5455577A (en) 1979-05-02
FI782363A (fi) 1979-02-02
AT368496B (de) 1982-10-11
DD143254A5 (de) 1980-08-13
ES472229A1 (es) 1979-03-16
GB2002758A (en) 1979-02-28
IL55254A (en) 1983-03-31
BE869415A (fr) 1979-01-31
GB2002758B (en) 1982-02-03
IE781550L (en) 1979-02-01
AU3847678A (en) 1980-02-07
DK339078A (da) 1979-02-02
IL55254A0 (en) 1978-09-29
FR2399429B1 (fr) 1981-07-17
AU523706B2 (en) 1982-08-12
FR2399429A1 (fr) 1979-03-02
CA1113096A (fr) 1981-11-24
LU80062A1 (fr) 1979-05-15
PL208757A1 (pl) 1979-06-04
SU862820A3 (ru) 1981-09-07
IE47014B1 (en) 1983-11-30
PL121492B1 (en) 1982-05-31
DE2833505A1 (de) 1979-04-05
NL7808067A (nl) 1979-02-05
ATA555478A (de) 1982-02-15
ZA784331B (en) 1979-12-27

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