DE2833505A1 - Tetrahydro-isochinolin-derivate, verfahren zu deren herstellung und mittel enthaltend die derivate - Google Patents

Tetrahydro-isochinolin-derivate, verfahren zu deren herstellung und mittel enthaltend die derivate

Info

Publication number
DE2833505A1
DE2833505A1 DE19782833505 DE2833505A DE2833505A1 DE 2833505 A1 DE2833505 A1 DE 2833505A1 DE 19782833505 DE19782833505 DE 19782833505 DE 2833505 A DE2833505 A DE 2833505A DE 2833505 A1 DE2833505 A1 DE 2833505A1
Authority
DE
Germany
Prior art keywords
compound
radicals
general formula
methoxy
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782833505
Other languages
German (de)
English (en)
Inventor
Sara Ginsburg
Richard J Kitz
John J Savarese
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of DE2833505A1 publication Critical patent/DE2833505A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19782833505 1977-08-01 1978-07-31 Tetrahydro-isochinolin-derivate, verfahren zu deren herstellung und mittel enthaltend die derivate Withdrawn DE2833505A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82079477A 1977-08-01 1977-08-01

Publications (1)

Publication Number Publication Date
DE2833505A1 true DE2833505A1 (de) 1979-04-05

Family

ID=25231743

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782833505 Withdrawn DE2833505A1 (de) 1977-08-01 1978-07-31 Tetrahydro-isochinolin-derivate, verfahren zu deren herstellung und mittel enthaltend die derivate

Country Status (21)

Country Link
JP (1) JPS5455577A (fr)
AT (1) AT368496B (fr)
AU (1) AU523706B2 (fr)
BE (1) BE869415A (fr)
CA (1) CA1113096A (fr)
DD (1) DD143254A5 (fr)
DE (1) DE2833505A1 (fr)
DK (1) DK339078A (fr)
ES (1) ES472229A1 (fr)
FI (1) FI782363A (fr)
FR (1) FR2399429A1 (fr)
GB (1) GB2002758B (fr)
IE (1) IE47014B1 (fr)
IL (1) IL55254A (fr)
LU (1) LU80062A1 (fr)
MC (1) MC1197A1 (fr)
NL (1) NL7808067A (fr)
PL (1) PL121492B1 (fr)
SE (1) SE7808267L (fr)
SU (1) SU862820A3 (fr)
ZA (1) ZA784331B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235906A (en) 1978-07-21 1980-11-25 Massachusetts General Hospital Bis-isoquinolinium compounds, compositions and methods of use
CA1125287A (fr) * 1978-07-21 1982-06-08 John J. Savarese Modes d'emploi de substances a base de bis-isoquinolinium
JPS5645459A (en) * 1979-09-20 1981-04-25 Otsuka Pharmaceut Co Ltd Cyclic amine
JPS5899465A (ja) * 1981-11-23 1983-06-13 ザ・ウエルカム・フアウンデ−シヨン・リミテツド イソキノリン誘導体
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
JPH0555438A (ja) * 1991-08-26 1993-03-05 Rohm Co Ltd 電子部品のリード端子構造
EA002224B1 (ru) * 1997-03-25 2002-02-28 Глаксо Груп Лимитед Замещенные изохинолины в качестве нервно-мышечных блокаторов ультракраткосрочного действия
ATE554769T1 (de) * 2006-12-06 2012-05-15 Cornell Res Foundation Inc Neuromuskuläre blocker mit mittlerer dauer und antagonisten advon
WO2010107488A1 (fr) 2009-03-17 2010-09-23 Cornell University Agents de blocage neuromusculaires non dépolarisants réversibles et leur méthode
WO2011022491A1 (fr) 2009-08-19 2011-02-24 Cornell University Cystéine pour injection physiologique
CN114057642B (zh) * 2021-12-10 2023-03-28 广东嘉博制药有限公司 一种米库氯铵中间体的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5156762U (fr) * 1974-10-28 1976-05-04

Also Published As

Publication number Publication date
FI782363A (fi) 1979-02-02
GB2002758A (en) 1979-02-28
FR2399429B1 (fr) 1981-07-17
BE869415A (fr) 1979-01-31
LU80062A1 (fr) 1979-05-15
DD143254A5 (de) 1980-08-13
IE781550L (en) 1979-02-01
DK339078A (da) 1979-02-02
AU3847678A (en) 1980-02-07
IL55254A (en) 1983-03-31
IL55254A0 (en) 1978-09-29
MC1197A1 (fr) 1979-03-19
AT368496B (de) 1982-10-11
AU523706B2 (en) 1982-08-12
SE7808267L (sv) 1979-02-02
ES472229A1 (es) 1979-03-16
FR2399429A1 (fr) 1979-03-02
PL121492B1 (en) 1982-05-31
CA1113096A (fr) 1981-11-24
ZA784331B (en) 1979-12-27
GB2002758B (en) 1982-02-03
ATA555478A (de) 1982-02-15
SU862820A3 (ru) 1981-09-07
NL7808067A (nl) 1979-02-05
JPS5455577A (en) 1979-05-02
IE47014B1 (en) 1983-11-30
PL208757A1 (pl) 1979-06-04

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee
8128 New person/name/address of the agent

Representative=s name: SCHWABE, H., DIPL.-ING. SANDMAIR, K., DIPL.-CHEM.