FR2399429A1 - Composes tetrahydro-isoquinoleiniques myorelaxants (agents de blocage de la plaque neuro-musculaire) et medicament contenant ces substances - Google Patents

Composes tetrahydro-isoquinoleiniques myorelaxants (agents de blocage de la plaque neuro-musculaire) et medicament contenant ces substances

Info

Publication number
FR2399429A1
FR2399429A1 FR7822577A FR7822577A FR2399429A1 FR 2399429 A1 FR2399429 A1 FR 2399429A1 FR 7822577 A FR7822577 A FR 7822577A FR 7822577 A FR7822577 A FR 7822577A FR 2399429 A1 FR2399429 A1 FR 2399429A1
Authority
FR
France
Prior art keywords
compounds
isoquinoleinic
myorelaxant
tetrahydro
substances
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7822577A
Other languages
English (en)
French (fr)
Other versions
FR2399429B1 (xx
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Original Assignee
General Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp filed Critical General Hospital Corp
Publication of FR2399429A1 publication Critical patent/FR2399429A1/fr
Application granted granted Critical
Publication of FR2399429B1 publication Critical patent/FR2399429B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
FR7822577A 1977-08-01 1978-07-31 Composes tetrahydro-isoquinoleiniques myorelaxants (agents de blocage de la plaque neuro-musculaire) et medicament contenant ces substances Granted FR2399429A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US82079477A 1977-08-01 1977-08-01

Publications (2)

Publication Number Publication Date
FR2399429A1 true FR2399429A1 (fr) 1979-03-02
FR2399429B1 FR2399429B1 (xx) 1981-07-17

Family

ID=25231743

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7822577A Granted FR2399429A1 (fr) 1977-08-01 1978-07-31 Composes tetrahydro-isoquinoleiniques myorelaxants (agents de blocage de la plaque neuro-musculaire) et medicament contenant ces substances

Country Status (21)

Country Link
JP (1) JPS5455577A (xx)
AT (1) AT368496B (xx)
AU (1) AU523706B2 (xx)
BE (1) BE869415A (xx)
CA (1) CA1113096A (xx)
DD (1) DD143254A5 (xx)
DE (1) DE2833505A1 (xx)
DK (1) DK339078A (xx)
ES (1) ES472229A1 (xx)
FI (1) FI782363A (xx)
FR (1) FR2399429A1 (xx)
GB (1) GB2002758B (xx)
IE (1) IE47014B1 (xx)
IL (1) IL55254A (xx)
LU (1) LU80062A1 (xx)
MC (1) MC1197A1 (xx)
NL (1) NL7808067A (xx)
PL (1) PL121492B1 (xx)
SE (1) SE7808267L (xx)
SU (1) SU862820A3 (xx)
ZA (1) ZA784331B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4235906A (en) 1978-07-21 1980-11-25 Massachusetts General Hospital Bis-isoquinolinium compounds, compositions and methods of use
CA1125287A (en) * 1978-07-21 1982-06-08 John J. Savarese Bis isoquinolinium compositions and methods of use
JPS5645459A (en) * 1979-09-20 1981-04-25 Otsuka Pharmaceut Co Ltd Cyclic amine
JPS5899465A (ja) * 1981-11-23 1983-06-13 ザ・ウエルカム・フアウンデ−シヨン・リミテツド イソキノリン誘導体
GB8418303D0 (en) * 1984-07-18 1984-08-22 Wellcome Found Compounds
JPH0555438A (ja) * 1991-08-26 1993-03-05 Rohm Co Ltd 電子部品のリード端子構造
CA2284802C (en) * 1997-03-25 2009-06-16 Cornell Research Foundation, Inc. Substituted isoquinolines as ultra short acting neuromuscular blockers
US8148398B2 (en) * 2006-12-06 2012-04-03 Cornell Research Foundation, Inc. Intermediate duration neuromuscular blocking agents and antagonists thereof
WO2010107488A1 (en) 2009-03-17 2010-09-23 Cornell University Reversible nondepolarizing neuromuscular blockade agents and methods for their use
US9220700B2 (en) 2009-08-19 2015-12-29 Cornell University Cysteine for physiological injection
CN114057642B (zh) * 2021-12-10 2023-03-28 广东嘉博制药有限公司 一种米库氯铵中间体的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5156762U (xx) * 1974-10-28 1976-05-04

Also Published As

Publication number Publication date
SE7808267L (sv) 1979-02-02
JPS5455577A (en) 1979-05-02
FI782363A (fi) 1979-02-02
AT368496B (de) 1982-10-11
DD143254A5 (de) 1980-08-13
ES472229A1 (es) 1979-03-16
GB2002758A (en) 1979-02-28
IL55254A (en) 1983-03-31
BE869415A (fr) 1979-01-31
MC1197A1 (fr) 1979-03-19
GB2002758B (en) 1982-02-03
IE781550L (en) 1979-02-01
AU3847678A (en) 1980-02-07
DK339078A (da) 1979-02-02
IL55254A0 (en) 1978-09-29
FR2399429B1 (xx) 1981-07-17
AU523706B2 (en) 1982-08-12
CA1113096A (en) 1981-11-24
LU80062A1 (fr) 1979-05-15
PL208757A1 (pl) 1979-06-04
SU862820A3 (ru) 1981-09-07
IE47014B1 (en) 1983-11-30
PL121492B1 (en) 1982-05-31
DE2833505A1 (de) 1979-04-05
NL7808067A (nl) 1979-02-05
ATA555478A (de) 1982-02-15
ZA784331B (en) 1979-12-27

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Legal Events

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ST Notification of lapse