FR2370732A1 - Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments - Google Patents

Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments

Info

Publication number
FR2370732A1
FR2370732A1 FR7735115A FR7735115A FR2370732A1 FR 2370732 A1 FR2370732 A1 FR 2370732A1 FR 7735115 A FR7735115 A FR 7735115A FR 7735115 A FR7735115 A FR 7735115A FR 2370732 A1 FR2370732 A1 FR 2370732A1
Authority
FR
France
Prior art keywords
piperidine
derivatives
polysubstitute
preparation
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7735115A
Other languages
English (en)
Other versions
FR2370732B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anphar SA
Original Assignee
Anphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anphar SA filed Critical Anphar SA
Publication of FR2370732A1 publication Critical patent/FR2370732A1/fr
Application granted granted Critical
Publication of FR2370732B1 publication Critical patent/FR2370732B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Abstract

Ces dérivés polysubstitués de la pipéridine ont pour formule générale :
FR7735115A 1976-11-16 1977-11-16 Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments Granted FR2370732A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47739/76A GB1574418A (en) 1976-11-16 1976-11-16 Piperidine derivatives

Publications (2)

Publication Number Publication Date
FR2370732A1 true FR2370732A1 (fr) 1978-06-09
FR2370732B1 FR2370732B1 (fr) 1980-07-04

Family

ID=10446086

Family Applications (2)

Application Number Title Priority Date Filing Date
FR7735115A Granted FR2370732A1 (fr) 1976-11-16 1977-11-16 Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments
FR7735116A Granted FR2370733A1 (fr) 1976-11-16 1977-11-16 Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments

Family Applications After (1)

Application Number Title Priority Date Filing Date
FR7735116A Granted FR2370733A1 (fr) 1976-11-16 1977-11-16 Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments

Country Status (13)

Country Link
US (1) US5026858A (fr)
JP (2) JPS5390267A (fr)
AT (2) AT360014B (fr)
AU (2) AU517830B2 (fr)
BE (2) BE860737A (fr)
CA (2) CA1095046A (fr)
DE (2) DE2751138A1 (fr)
ES (4) ES464145A1 (fr)
FR (2) FR2370732A1 (fr)
GB (1) GB1574418A (fr)
IE (2) IE45989B1 (fr)
NL (2) NL7712570A (fr)
ZA (2) ZA776587B (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2546169A1 (fr) * 1983-05-20 1984-11-23 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
WO2005053663A2 (fr) * 2003-11-24 2005-06-16 Eli Lilly And Company Traitement de la defaillance cognitive

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1574418A (en) * 1976-11-16 1980-09-03 Anphar Sa Piperidine derivatives
US5011992A (en) * 1984-06-28 1991-04-30 Bristol-Myers Squibb Company Pharmacologically active substituted benzamides
US4820715A (en) * 1984-06-28 1989-04-11 Bristol-Myers Company Anti-emetic quinuclidinyl benzamides
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
GB8519707D0 (en) * 1985-08-06 1985-09-11 Fordonal Sa Chemical compounds
CA2141048C (fr) * 1992-08-19 2003-03-18 Harry R. Howard Derives de substitution benzylamino d'heterocycles non aromatiques azotes
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5885983A (en) * 1996-05-10 1999-03-23 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5827875A (en) * 1996-05-10 1998-10-27 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5883109A (en) * 1996-07-24 1999-03-16 Bristol-Myers Squibb Company Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
US6339087B1 (en) 1997-08-18 2002-01-15 Syntex (U.S.A.) Llc Cyclic amine derivatives-CCR-3 receptor antagonists
IL125658A0 (en) 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
BR9915735A (pt) * 1998-11-20 2001-09-04 Hoffmann La Roche Antagonistas receptores de ccr-3 de piperidina
FR2802206B1 (fr) 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
TWI295669B (en) * 2002-10-30 2008-04-11 Theravance Inc Substituted 4-amino-1-(pyridylmethyl) piperidine and related compounds
US7368463B2 (en) * 2003-07-11 2008-05-06 Theravance, Inc. Substituted 4-amino-1-benzylpiperidine compounds
ATE445612T1 (de) * 2005-06-02 2009-10-15 Hoffmann La Roche Piperidin-4-yl-amidderivate und ihre verwendung als antagonisten des sst-rezeptors vom subtyp 5
JP2009264436A (ja) 2008-04-23 2009-11-12 Funai Electric Co Ltd トルクリミッタ装置、トルクリミッタ装置を備えた表示画面旋回装置およびトルクリミッタ装置を含むテレビジョン装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1407055A (fr) * 1963-03-05 1965-07-30 Ile De France Nouveau procédé de préparation de benzamides substitués
GB1019781A (fr) * 1963-03-05
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR5916M (fr) * 1966-01-21 1968-05-06
US3577440A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-amido-pyrrolidines
GB1345872A (en) * 1970-09-03 1974-02-06 Wyeth John & Brother Ltd Amino-and acylamino-pyridine and hydropyridine derivatives
US3963745A (en) * 1972-04-03 1976-06-15 A. H. Robins Company, Incorporated Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
DE2513136C3 (de) * 1974-03-21 1981-04-30 Anphar S.A., Madrid N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
GB1513631A (en) * 1976-02-17 1978-06-07 Gallardo Antonio Sa Piperidine derivatives
US4163789A (en) * 1976-02-17 1979-08-07 Anphar, S.A. Anti-psychotic (cycloalkenylalkylpiperidino) benzamides
GB1574418A (en) * 1976-11-16 1980-09-03 Anphar Sa Piperidine derivatives

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2546169A1 (fr) * 1983-05-20 1984-11-23 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
WO2005053663A2 (fr) * 2003-11-24 2005-06-16 Eli Lilly And Company Traitement de la defaillance cognitive
WO2005053663A3 (fr) * 2003-11-24 2005-08-11 Lilly Co Eli Traitement de la defaillance cognitive

Also Published As

Publication number Publication date
GB1574418A (en) 1980-09-03
IE45989B1 (en) 1983-01-26
AU3067377A (en) 1979-05-24
ES464146A1 (es) 1978-09-01
JPS5387365A (en) 1978-08-01
IE46090B1 (en) 1983-02-23
AU3067277A (en) 1979-05-24
AT360014B (de) 1980-12-10
DE2751138A1 (de) 1978-05-24
ATA817177A (de) 1980-05-15
ZA776587B (en) 1978-09-27
CA1095046A (fr) 1981-02-03
BE860736A (fr) 1978-03-01
AU517004B2 (en) 1981-07-02
JPS6126782B2 (fr) 1986-06-21
FR2370732B1 (fr) 1980-07-04
ATA817077A (de) 1980-05-15
ZA776588B (en) 1978-08-30
NL7712570A (nl) 1978-05-18
IE46090L (en) 1978-05-16
CA1094072A (fr) 1981-01-20
ES464145A1 (es) 1978-09-01
AT360013B (de) 1980-12-10
DE2751139A1 (de) 1978-05-24
ES464147A1 (es) 1978-09-01
FR2370733A1 (fr) 1978-06-09
US5026858A (en) 1991-06-25
FR2370733B1 (fr) 1980-07-04
JPS5390267A (en) 1978-08-08
NL7712559A (nl) 1978-05-18
ES464144A1 (es) 1978-09-01
BE860737A (fr) 1978-03-01
JPS6127388B2 (fr) 1986-06-25
AU517830B2 (en) 1981-08-27
IE45989L (en) 1978-05-16

Similar Documents

Publication Publication Date Title
FR2370732A1 (fr) Derives polysubstitues de la piperidine, leurs procedes de preparation et leur application en tant que medicaments
FR2370731A1 (fr) Nouveaux derives de la piperidine polysubstitues, leurs procedes de preparation et leur application pharmaceutique
FR2367053A1 (fr) Nouveaux derives de phenoxy-amino-propanol, leur preparation et leur application en tant que medicaments
FR2422620A1 (fr) Derives du stilbene, leur preparation et leur application en tant que medicaments
FR2400512A1 (fr) Nouveaux nitro-imidazoles, leur preparation et leur application en tant que medicaments
FR2390428A1 (fr) Nouveaux composes polyeniques, leur preparation et leur application en tant que medicaments
FR2392971A1 (fr) Derives de l'acide prostanoique, leur preparation et medicament contenant ces substances
FR2387954A1 (fr) Derives de mercaptoalkylsulfonylproline et composes apparentes, et leur utilisation comme medicaments
FR2422643A1 (fr) Nouveaux derives d'imidazolidine, leur preparation et leur application comme medicaments
FR2445319A1 (fr) Derives de pyridine, procedes pour leur preparation et compositions pharmaceutiques les contenant
FR2360601A1 (fr) Nouveaux derives d'acides phosphoneux, leur preparation et leur application en tant que medicaments
FR2384774A1 (fr) Nouveaux derives de la morphine et application a titre de medicament.
FR2427335A1 (fr) Derives du 5-nitro-imidazole, leur preparation et leurs utilisations comme medicaments antiprotozoaires
FR2415103A1 (fr) Acides et derives d'acides 4-pyridone-3-carboxyliques, leur preparation et leur application en tant que medicaments
FR2378014A1 (fr) Nouveaux derives aminoalcoxyphenyles, leur preparation et leur utilisation en tant que medicaments
FR2355021A1 (fr) Nouveaux derives d'imidazothiazine et leur application en tant que medicaments
FR2355007A1 (fr) (3-alcoyle inferieur-amino-2-r, 10 propoxy pyridines substituees, leur preparation et leur application en tant que medicaments
FR2397385A1 (fr) Derives du resorcinol, leur preparation et leurs utilisations therapeutiques
FR2416886A1 (fr) Nouveaux derives de la 3-phenyl-tetrahydropyridine et leurs sels, procedes de preparation et application a titre de medicaments
FR2379538A1 (fr) Nouveaux derives d'oxadiazolopyrimidine, leur preparation et leur application en tant que medicaments
FR2355012A1 (fr) Nouveaux derives de dihydro- et tetrahydro-iminothiazine, et leur application en tant que medicaments
FR2401160A1 (fr) Nouveaux derives d'esters de vincaminol, leur preparation et leur application en tant que medicaments
FR2358151A1 (fr) Nouvelles benzazepines et leurs sels, procede de preparation et application a titre de medicaments
FR2421181A1 (fr) Derives de substitution de spirooxazolidinone steroidienne, leur procede de preparation et compositions pharmaceutiques les contenant
FR2373285A1 (fr) Nouveaux derives du coenzyme b 12, procede de preparation et application a titre de medicaments de ces nouveaux produits

Legal Events

Date Code Title Description
CD Change of name or company name
ST Notification of lapse