ES464144A1 - Procedimiento de preparacion de compuestos derivados de la piperidina. - Google Patents

Procedimiento de preparacion de compuestos derivados de la piperidina.

Info

Publication number
ES464144A1
ES464144A1 ES464144A ES464144A ES464144A1 ES 464144 A1 ES464144 A1 ES 464144A1 ES 464144 A ES464144 A ES 464144A ES 464144 A ES464144 A ES 464144A ES 464144 A1 ES464144 A1 ES 464144A1
Authority
ES
Spain
Prior art keywords
pharmaceutical compositions
relates
piperidine derivative
piperidine
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES464144A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anphar SA
Original Assignee
Anphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anphar SA filed Critical Anphar SA
Publication of ES464144A1 publication Critical patent/ES464144A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento de preparación de derivados de la piperidina de fórmula general **(Fórmula)** en donde R representa un átomo de halógeno o un grupo hidroxi, alcoxi inferior, alqueniloxi inferior, alquiniloxi inferior o aralquiloxí o un grupo aciloxi inferior en el cual el grupo acilo se deriva de un ácido carboxílico; R1 representa un átomo de hidrógeno o un grupo amino, alquilamino inferior, dialquilamino inferior o un acilamino inferior en el cual el grupo acilo se deriva de un ácido carboxílico; R2 representa un grupo nitro, trifluoromotílo o alquuiltio inferior o Rl y R2 juntos forman un grupo triazo (es decir -HN-N=N-); R3 representa un átomo de hidrógeno ó un alquilo inferior ó alquenilo inferior, o un grupo cícloalquilo o cicloalquenilo teniendo de 3 a.7 átomos de carbono en el anillo,o un grupo fenilo, R4 representa un grupo cicloalquenilo teniendo 3 a 7 átomos de carbono en el anillo, opcionalmente sustituido por un grupo alquilo inferior o alquenilo inferior; R5, R6 y R7 representan cada uno un átomo de hidrógeno, un grupo alquilo inferior, alquenilo inferior o un grupo bencilo, y W representa un enlace sencillo o un grupo alquileno inferior o alquenileno inferior.
ES464144A 1976-11-16 1977-11-15 Procedimiento de preparacion de compuestos derivados de la piperidina. Expired ES464144A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB47739/76A GB1574418A (en) 1976-11-16 1976-11-16 Piperidine derivatives

Publications (1)

Publication Number Publication Date
ES464144A1 true ES464144A1 (es) 1978-09-01

Family

ID=10446086

Family Applications (4)

Application Number Title Priority Date Filing Date
ES464147A Expired ES464147A1 (es) 1976-11-16 1977-11-15 Procedimiento de preparacion de derivados de la piperidina.
ES464145A Expired ES464145A1 (es) 1976-11-16 1977-11-15 Procedimiento de preparacion de compuestos derivados de la piperidina.
ES464144A Expired ES464144A1 (es) 1976-11-16 1977-11-15 Procedimiento de preparacion de compuestos derivados de la piperidina.
ES464146A Expired ES464146A1 (es) 1976-11-16 1977-11-15 Procedimiento de preparacion de derivados de la piperidina.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES464147A Expired ES464147A1 (es) 1976-11-16 1977-11-15 Procedimiento de preparacion de derivados de la piperidina.
ES464145A Expired ES464145A1 (es) 1976-11-16 1977-11-15 Procedimiento de preparacion de compuestos derivados de la piperidina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES464146A Expired ES464146A1 (es) 1976-11-16 1977-11-15 Procedimiento de preparacion de derivados de la piperidina.

Country Status (13)

Country Link
US (1) US5026858A (es)
JP (2) JPS5390267A (es)
AT (2) AT360013B (es)
AU (2) AU517004B2 (es)
BE (2) BE860736A (es)
CA (2) CA1094072A (es)
DE (2) DE2751139A1 (es)
ES (4) ES464147A1 (es)
FR (2) FR2370732A1 (es)
GB (1) GB1574418A (es)
IE (2) IE45989B1 (es)
NL (2) NL7712559A (es)
ZA (2) ZA776587B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1574418A (en) * 1976-11-16 1980-09-03 Anphar Sa Piperidine derivatives
FR2546169B1 (fr) * 1983-05-20 1986-03-21 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
US4820715A (en) * 1984-06-28 1989-04-11 Bristol-Myers Company Anti-emetic quinuclidinyl benzamides
US5011992A (en) * 1984-06-28 1991-04-30 Bristol-Myers Squibb Company Pharmacologically active substituted benzamides
US4808624A (en) * 1984-06-28 1989-02-28 Bristol-Myers Company Pharmacologically active substituted benzamides
GB8519707D0 (en) * 1985-08-06 1985-09-11 Fordonal Sa Chemical compounds
AU4224993A (en) * 1992-08-19 1994-03-15 Pfizer Inc. Substituted benzylamino nitrogen containing non-aromatic heterocycles
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5885983A (en) * 1996-05-10 1999-03-23 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5827875A (en) * 1996-05-10 1998-10-27 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5883109A (en) * 1996-07-24 1999-03-16 Bristol-Myers Squibb Company Method for lowering serum lipid levels employing an MTP inhibitor in combination with another cholesterol lowering drug
IL125658A0 (en) 1997-08-18 1999-04-11 Hoffmann La Roche Ccr-3 receptor antagonists
US6339087B1 (en) 1997-08-18 2002-01-15 Syntex (U.S.A.) Llc Cyclic amine derivatives-CCR-3 receptor antagonists
KR20010081034A (ko) * 1998-11-20 2001-08-25 프리돌린 클라우스너, 롤란드 비. 보레르 피페리딘 씨씨알-3 수용체 길항제
FR2802206B1 (fr) * 1999-12-14 2005-04-22 Sod Conseils Rech Applic Derives de 4-aminopiperidine et leur utilisation en tant que medicament
TW200800953A (en) * 2002-10-30 2008-01-01 Theravance Inc Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine
WO2005007645A1 (en) * 2003-07-11 2005-01-27 Theravance, Inc. Substituted 4-amino-1-benzylpiperidine compounds
WO2005053663A2 (en) * 2003-11-24 2005-06-16 Eli Lilly And Company Norepinephrine reuptake inhibitors useful for treatment of cognitive failure
RU2403250C2 (ru) * 2005-06-02 2010-11-10 Ф.Хоффманн-Ля Рош Аг Производные пиперидин-4-иламида и их применение в качестве антагонистов рецептора sst подтипа 5
JP2009264436A (ja) 2008-04-23 2009-11-12 Funai Electric Co Ltd トルクリミッタ装置、トルクリミッタ装置を備えた表示画面旋回装置およびトルクリミッタ装置を含むテレビジョン装置

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1019781A (es) * 1963-03-05
FR1407055A (fr) * 1963-03-05 1965-07-30 Ile De France Nouveau procédé de préparation de benzamides substitués
US3342826A (en) * 1964-01-13 1967-09-19 Ile De France Heterocyclic aminoalkyl benzamides
FR5916M (es) * 1966-01-21 1968-05-06
US3577440A (en) * 1968-12-23 1971-05-04 Robins Co Inc A H 1-substituted-3-amido-pyrrolidines
GB1345872A (en) * 1970-09-03 1974-02-06 Wyeth John & Brother Ltd Amino-and acylamino-pyridine and hydropyridine derivatives
US3963745A (en) * 1972-04-03 1976-06-15 A. H. Robins Company, Incorporated Method for controlling emesis with N-(1-substituted-3-pyrrolidinyl)benzamides and thiobenzamides
DE2513136C3 (de) * 1974-03-21 1981-04-30 Anphar S.A., Madrid N-(1-Benzylpiperid-4-yl)-benzamide, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate
US4163789A (en) * 1976-02-17 1979-08-07 Anphar, S.A. Anti-psychotic (cycloalkenylalkylpiperidino) benzamides
GB1513631A (en) * 1976-02-17 1978-06-07 Gallardo Antonio Sa Piperidine derivatives
GB1574418A (en) * 1976-11-16 1980-09-03 Anphar Sa Piperidine derivatives

Also Published As

Publication number Publication date
FR2370733B1 (es) 1980-07-04
AT360013B (de) 1980-12-10
IE46090L (en) 1978-05-16
IE45989L (en) 1978-05-16
FR2370733A1 (fr) 1978-06-09
BE860737A (fr) 1978-03-01
AU3067377A (en) 1979-05-24
AU517830B2 (en) 1981-08-27
FR2370732B1 (es) 1980-07-04
DE2751139A1 (de) 1978-05-24
JPS5387365A (en) 1978-08-01
JPS6127388B2 (es) 1986-06-25
JPS6126782B2 (es) 1986-06-21
ES464145A1 (es) 1978-09-01
CA1094072A (en) 1981-01-20
ES464147A1 (es) 1978-09-01
ATA817177A (de) 1980-05-15
AT360014B (de) 1980-12-10
GB1574418A (en) 1980-09-03
NL7712570A (nl) 1978-05-18
ATA817077A (de) 1980-05-15
IE45989B1 (en) 1983-01-26
US5026858A (en) 1991-06-25
BE860736A (fr) 1978-03-01
AU517004B2 (en) 1981-07-02
ZA776588B (en) 1978-08-30
DE2751138A1 (de) 1978-05-24
IE46090B1 (en) 1983-02-23
ES464146A1 (es) 1978-09-01
JPS5390267A (en) 1978-08-08
CA1095046A (en) 1981-02-03
FR2370732A1 (fr) 1978-06-09
ZA776587B (en) 1978-09-27
AU3067277A (en) 1979-05-24
NL7712559A (nl) 1978-05-18

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Legal Events

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PC1A Transfer granted