ES8800200A1 - Un proceso para produccion de un derivado del indol. - Google Patents

Un proceso para produccion de un derivado del indol.

Info

Publication number
ES8800200A1
ES8800200A1 ES551921A ES551921A ES8800200A1 ES 8800200 A1 ES8800200 A1 ES 8800200A1 ES 551921 A ES551921 A ES 551921A ES 551921 A ES551921 A ES 551921A ES 8800200 A1 ES8800200 A1 ES 8800200A1
Authority
ES
Spain
Prior art keywords
indole derivatives
production
new indole
gastric
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551921A
Other languages
English (en)
Other versions
ES551921A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MSD KK
Original Assignee
Banyu Phamaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Banyu Phamaceutical Co Ltd filed Critical Banyu Phamaceutical Co Ltd
Publication of ES551921A0 publication Critical patent/ES551921A0/es
Publication of ES8800200A1 publication Critical patent/ES8800200A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO DE INDOL, DE FORMULA (I), Y DE SUS SALES. COMPRENDE LA REACCION DE UN COMPUESTO TIOL DE FORMULA (II), O UNO DE SUS DERIVADOS FUNCIONALMENTE EQUIVALENTE, CON UN COMPUESTO DE PIRIDINA DE FORMULA (III), O UNA DE SUS SALES, PARA OBTENER UN COMPUESTO DE FORMULA (I), EN LAS QUE X ELEVADO A 1 ES UN GRUPO RESIDUAL, R ELEVADO A 1 - R ELEVADO A 5 PUEDEN SER VARIOS RADICALES, Y N, P Y Q VALEN 0 O 1, 1-4 Y 1-3, RESPECTIVAMENTE. LA REACCION SE EFECTUA EN UN DISOLVENTE INERTE, A UNA TEMPERATURA COMPRENDIDA ENTRE 0GC Y 150GC. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ULCERA GASTROINTESTINAL. *FORMULA*
ES551921A 1985-02-12 1986-02-12 Un proceso para produccion de un derivado del indol. Expired ES8800200A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2358585 1985-02-12
JP25364885 1985-11-14

Publications (2)

Publication Number Publication Date
ES551921A0 ES551921A0 (es) 1987-11-01
ES8800200A1 true ES8800200A1 (es) 1987-11-01

Family

ID=26360969

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551921A Expired ES8800200A1 (es) 1985-02-12 1986-02-12 Un proceso para produccion de un derivado del indol.

Country Status (7)

Country Link
US (1) US4743609A (es)
EP (1) EP0194458B1 (es)
KR (1) KR860006455A (es)
AT (1) ATE44029T1 (es)
DE (1) DE3663947D1 (es)
ES (1) ES8800200A1 (es)
HU (1) HU196789B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5945425A (en) 1994-04-29 1999-08-31 G.D. Searle & Co. Method of using (H+ /K+)ATPase inhibitors as antiviral agents
US5965582A (en) * 1994-08-03 1999-10-12 Asta Medica Aktiengesellschaft N-benzylindole and benzopyrazole derivatives with anti-asthmatic, anti-allergic, anti-inflammatory and immunemodulating effect
PT1286669E (pt) * 2000-05-30 2010-09-20 Merial Ltd Composições para a prevenção de úlceras em cavalos
WO2007020653A1 (en) * 2005-08-12 2007-02-22 Suven Life Sciences Limited Thioether derivatives as functional 5-ht6 ligands

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4472409A (en) * 1981-11-05 1984-09-18 Byk Gulden Lomberg Chemische Fabrik Gesellschaft Mit Beschrankter Haftung 2-Pyridylmethyl thio(sulfinyl)benzimidazoles with gastric acid secretion inhibiting effects
US4575554A (en) * 1983-12-05 1986-03-11 The Upjohn Company Substituted 2-pyridylmethylthio- and sulfinyl-benzimidazoles as gastric antisecretory agents

Also Published As

Publication number Publication date
KR860006455A (ko) 1986-09-11
US4743609A (en) 1988-05-10
HUT40110A (en) 1986-11-28
ES551921A0 (es) 1987-11-01
HU196789B (en) 1989-01-30
DE3663947D1 (en) 1989-07-20
EP0194458A1 (en) 1986-09-17
ATE44029T1 (de) 1989-06-15
EP0194458B1 (en) 1989-06-14

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20001009