FR2370731A1 - Nouveaux derives de la piperidine polysubstitues, leurs procedes de preparation et leur application pharmaceutique - Google Patents

Nouveaux derives de la piperidine polysubstitues, leurs procedes de preparation et leur application pharmaceutique

Info

Publication number
FR2370731A1
FR2370731A1 FR7735106A FR7735106A FR2370731A1 FR 2370731 A1 FR2370731 A1 FR 2370731A1 FR 7735106 A FR7735106 A FR 7735106A FR 7735106 A FR7735106 A FR 7735106A FR 2370731 A1 FR2370731 A1 FR 2370731A1
Authority
FR
France
Prior art keywords
polysubstitues
piperidine
preparation
methods
new derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7735106A
Other languages
English (en)
Other versions
FR2370731B1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Anphar SA
Original Assignee
Anphar SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anphar SA filed Critical Anphar SA
Publication of FR2370731A1 publication Critical patent/FR2370731A1/fr
Application granted granted Critical
Publication of FR2370731B1 publication Critical patent/FR2370731B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Ces dérivés ont comme formule générale :
FR7735106A 1976-11-16 1977-11-15 Nouveaux derives de la piperidine polysubstitues, leurs procedes de preparation et leur application pharmaceutique Granted FR2370731A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4773876A GB1575310A (en) 1976-11-16 1976-11-16 Piperidine derivatives

Publications (2)

Publication Number Publication Date
FR2370731A1 true FR2370731A1 (fr) 1978-06-09
FR2370731B1 FR2370731B1 (fr) 1980-05-16

Family

ID=10446083

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7735106A Granted FR2370731A1 (fr) 1976-11-16 1977-11-15 Nouveaux derives de la piperidine polysubstitues, leurs procedes de preparation et leur application pharmaceutique

Country Status (5)

Country Link
JP (1) JPS5387364A (fr)
DE (1) DE2751181A1 (fr)
ES (2) ES464148A1 (fr)
FR (1) FR2370731A1 (fr)
GB (1) GB1575310A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0033529A1 (fr) * 1980-02-02 1981-08-12 Chemische Werke Hüls Ag Procédé de préparation d'amino-4 tétraméthyl-2,2,6,6 pipéridine
FR2534255A1 (fr) * 1982-10-11 1984-04-13 Delalande Sa Nouveaux derives de la 4-aroylamino piperidine, leur procede de preparation et leur application en therapeutique
FR2546169A1 (fr) * 1983-05-20 1984-11-23 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
EP0645391A2 (fr) * 1993-07-30 1995-03-29 Eisai Co., Ltd. Dérivés d'acide aminobenzoique

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4962115A (en) * 1981-10-01 1990-10-09 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl)benzamide derivatives
US5057525A (en) * 1981-10-01 1991-10-15 Janssen Pharmaceutica N.V. Novel N-(3-hydroxy-4-piperidinyl) benzamide derivatives
US5137896A (en) * 1981-10-01 1992-08-11 Janssen Pharmaceutica N.V. N-(3-hydroxy-4-piperidinyl)benzamide derivatives
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
US6517811B2 (en) 1993-05-06 2003-02-11 Research Corporation Technologies, Inc. Compounds for cancer imaging and therapy
AU1057101A (en) * 1999-11-17 2001-05-30 Kissei Pharmaceutical Co. Ltd. Hydroxyethoxybenzamide derivatives and drugs containing the same
TW200800953A (en) 2002-10-30 2008-01-01 Theravance Inc Intermediates for preparing substituted 4-amino-1-(pyridylmethyl) piperidine
WO2004046110A1 (fr) * 2002-11-15 2004-06-03 Yamanouchi Pharmaceutical Co., Ltd. Antagoniste du recepteur d'hormone de concentration de la melanine
WO2005007645A1 (fr) 2003-07-11 2005-01-27 Theravance, Inc. Composes de 4-amino-1-benzylpiperidine substitues
US8673920B2 (en) 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9073882B2 (en) 2010-10-27 2015-07-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9056859B2 (en) 2010-10-29 2015-06-16 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2744499B1 (fr) 2011-08-19 2016-09-28 Merck Sharp & Dohme Corp. Inhibiteurs du canal potassique médullaire externe rénal
TW201317213A (zh) 2011-09-16 2013-05-01 Merck Sharp & Dohme 腎外髓質鉀通道抑制劑
US8999991B2 (en) 2011-10-25 2015-04-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013062892A1 (fr) 2011-10-25 2013-05-02 Merck Sharp & Dohme Corp. Inhibiteurs du canal potassique médullaire extérieur rénal
EP2773206B1 (fr) 2011-10-31 2018-02-21 Merck Sharp & Dohme Corp. Inhibiteurs du canal potassique médullaire externe rénal
WO2013066718A2 (fr) 2011-10-31 2013-05-10 Merck Sharp & Dohme Corp. Inhibiteurs du canal potassique médullaire externe rénal
US9139585B2 (en) 2011-10-31 2015-09-22 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
WO2013090271A1 (fr) 2011-12-16 2013-06-20 Merck Sharp & Dohme Corp. Inhibiteurs du canal à potassium de la medulla externe du rein
AR092031A1 (es) 2012-07-26 2015-03-18 Merck Sharp & Dohme Inhibidores del canal de potasio medular externo renal
EP2925322B1 (fr) 2012-11-29 2018-10-24 Merck Sharp & Dohme Corp. Inhibiteurs du canal potassique médullaire extérieur rénal
EP2934533B1 (fr) 2012-12-19 2017-11-15 Merck Sharp & Dohme Corp. Inhibiteurs du canal potassique médullaire externe rénal
US9604998B2 (en) 2013-02-18 2017-03-28 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2968288B1 (fr) 2013-03-15 2018-07-04 Merck Sharp & Dohme Corp. Inhibiteurs du canal potassique médullaire extérieur rénal
US9751881B2 (en) 2013-07-31 2017-09-05 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2016127358A1 (fr) 2015-02-12 2016-08-18 Merck Sharp & Dohme Corp. Inhibiteurs du canal potassique médullaire externe rénal

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0033529A1 (fr) * 1980-02-02 1981-08-12 Chemische Werke Hüls Ag Procédé de préparation d'amino-4 tétraméthyl-2,2,6,6 pipéridine
EP0033529B1 (fr) * 1980-02-02 1984-09-26 Chemische Werke Hüls Ag Procédé de préparation d'amino-4 tétraméthyl-2,2,6,6 pipéridine
FR2534255A1 (fr) * 1982-10-11 1984-04-13 Delalande Sa Nouveaux derives de la 4-aroylamino piperidine, leur procede de preparation et leur application en therapeutique
FR2546169A1 (fr) * 1983-05-20 1984-11-23 Delalande Sa N-oxydes de derives aminocycliques, leur procede de preparation et leur application en therapeutique
EP0645391A2 (fr) * 1993-07-30 1995-03-29 Eisai Co., Ltd. Dérivés d'acide aminobenzoique
EP0645391A3 (fr) * 1993-07-30 1995-05-24 Eisai Co Ltd Dérivés d'acide aminobenzoique.
US5512579A (en) * 1993-07-30 1996-04-30 Eisai Co., Ltd. Aminobenzoic acid derivatives
US5658925A (en) * 1993-07-30 1997-08-19 Eisai Co., Ltd. Aminobenzoic acid derivatives
US5677311A (en) * 1993-07-30 1997-10-14 Eisai Co., Ltd. Aminobenzoic acid derivatives
US5723472A (en) * 1993-07-30 1998-03-03 Eisai Co., Ltd. Aminobenzoic acid derivatives
US5861418A (en) * 1993-07-30 1999-01-19 Eisai Co., Ltd. Aminobenzoic acid derivatives

Also Published As

Publication number Publication date
DE2751181A1 (de) 1978-05-24
JPS5387364A (en) 1978-08-01
FR2370731B1 (fr) 1980-05-16
GB1575310A (en) 1980-09-17
ES464149A1 (es) 1978-09-01
ES464148A1 (es) 1978-09-01

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