DE2750090A1 - Neue verabreichungsformen fuer organische verbindungen - Google Patents

Neue verabreichungsformen fuer organische verbindungen

Info

Publication number
DE2750090A1
DE2750090A1 DE19772750090 DE2750090A DE2750090A1 DE 2750090 A1 DE2750090 A1 DE 2750090A1 DE 19772750090 DE19772750090 DE 19772750090 DE 2750090 A DE2750090 A DE 2750090A DE 2750090 A1 DE2750090 A1 DE 2750090A1
Authority
DE
Germany
Prior art keywords
hydrogen
nasal
administration
formula
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19772750090
Other languages
German (de)
English (en)
Inventor
Moise Dr Azria
Thomas Dr Cavanak
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of DE2750090A1 publication Critical patent/DE2750090A1/de
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D2207/00—Indexing scheme relating to details of indicating measuring values
    • G01D2207/10—Displays which are primarily used in aircraft or display aircraft-specific information

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE19772750090 1976-11-19 1977-11-09 Neue verabreichungsformen fuer organische verbindungen Ceased DE2750090A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1457576 1976-11-19
CH698977 1977-06-07

Publications (1)

Publication Number Publication Date
DE2750090A1 true DE2750090A1 (de) 1978-06-01

Family

ID=25700540

Family Applications (2)

Application Number Title Priority Date Filing Date
DE19772750090 Ceased DE2750090A1 (de) 1976-11-19 1977-11-09 Neue verabreichungsformen fuer organische verbindungen
DE19782802113 Withdrawn DE2802113A1 (de) 1976-11-19 1978-01-19 Neue verabreichungsformen fuer organische verbindungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE19782802113 Withdrawn DE2802113A1 (de) 1976-11-19 1978-01-19 Neue verabreichungsformen fuer organische verbindungen

Country Status (27)

Country Link
US (2) US4462983A (cg-RX-API-DMAC7.html)
JP (1) JPS5366440A (cg-RX-API-DMAC7.html)
AT (1) AT368881B (cg-RX-API-DMAC7.html)
AU (1) AU520754B2 (cg-RX-API-DMAC7.html)
CA (1) CA1103585A (cg-RX-API-DMAC7.html)
CS (2) CS228502B2 (cg-RX-API-DMAC7.html)
CY (1) CY1266A (cg-RX-API-DMAC7.html)
DE (2) DE2750090A1 (cg-RX-API-DMAC7.html)
DK (1) DK153440C (cg-RX-API-DMAC7.html)
ES (1) ES464275A1 (cg-RX-API-DMAC7.html)
FI (1) FI773376A7 (cg-RX-API-DMAC7.html)
FR (1) FR2371454A1 (cg-RX-API-DMAC7.html)
GB (1) GB1592563A (cg-RX-API-DMAC7.html)
GR (1) GR65229B (cg-RX-API-DMAC7.html)
HK (1) HK85984A (cg-RX-API-DMAC7.html)
HU (1) HU185924B (cg-RX-API-DMAC7.html)
IE (1) IE46167B1 (cg-RX-API-DMAC7.html)
IL (1) IL53419A (cg-RX-API-DMAC7.html)
KE (1) KE3453A (cg-RX-API-DMAC7.html)
MY (1) MY8400055A (cg-RX-API-DMAC7.html)
NL (1) NL187892C (cg-RX-API-DMAC7.html)
NO (1) NO773839L (cg-RX-API-DMAC7.html)
NZ (1) NZ185711A (cg-RX-API-DMAC7.html)
PH (1) PH23643A (cg-RX-API-DMAC7.html)
PT (1) PT67292B (cg-RX-API-DMAC7.html)
SE (1) SE451944B (cg-RX-API-DMAC7.html)
SG (1) SG61784G (cg-RX-API-DMAC7.html)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3302949A1 (de) * 1982-02-01 1983-08-11 Sandoz-Patent-GmbH, 7850 Lörrach Nasal verabreichbare pharmazeutische zusammensetzungen

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DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
US4284648A (en) * 1979-08-03 1981-08-18 The University Of Kentucky Research Foundation Nasal administration of propranolol
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
GB8413795D0 (en) * 1984-05-30 1984-07-04 Sandoz Ltd Organic compounds
GB8426922D0 (en) * 1984-10-24 1984-11-28 Sandoz Ltd Galenic formulation
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
FR2628638B1 (fr) * 1985-03-06 1992-12-18 Sandoz Lab Dispositif de pulverisation par voie nasale d'une dose unitaire de medicament en solution
JPS61263918A (ja) * 1985-05-16 1986-11-21 Banyu Pharmaceut Co Ltd 経皮吸収用製剤
ATE78158T1 (de) * 1985-05-22 1992-08-15 Liposome Technology Inc Verfahren und system zum einatmen von liposomen.
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
US4782047A (en) * 1986-05-22 1988-11-01 Syntex Pharmaceuticals International Ltd. Aqueous steroid formulations for nasal administration
US4897256A (en) * 1986-11-25 1990-01-30 Abbott Laboratories LHRH analog formulations
DE3710216A1 (de) * 1987-03-27 1988-10-06 Rentschler Arzneimittel Verwendung von dihydroergotamin und seinen salzen zur lokalen behandlung trophischer stoerungen
GB2216794B (en) * 1988-03-22 1991-11-20 Fisons Plc Pharmaceuticals compositions
US4929640A (en) * 1988-04-04 1990-05-29 George D. McAdory Medicaments intended for combined use in the improvement of lymphocyte function
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
IT1247472B (it) * 1991-05-31 1994-12-17 Fidia Spa Processo per la preparazione di microsfere contenenti componenti biologicamente attivi.
WO1993025193A1 (fr) * 1992-06-12 1993-12-23 Teijin Limited Preparation pharmaceutique destinee a etre administree par les voies respiratoires
EP0611567B1 (en) * 1992-06-12 2002-08-28 Teijin Limited Ultrafine powder for inhalation and production thereof
DE69434304T2 (de) * 1993-03-26 2005-12-29 Merkus, Franciscus Wilhelmus H.M. Pharmazeutische Zusammensetzungen zur intranasalen Verabreichung von Dihydroergotamin
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
SE9404468D0 (sv) * 1994-12-22 1994-12-22 Astra Ab Powder formulations
JP4155594B2 (ja) 1994-12-22 2008-09-24 アストラゼネカ・アクチエボラーグ エアゾール製剤
EP1283035A3 (en) * 1994-12-22 2003-03-19 AstraZeneca AB Therapeutic preparation for inhalation containing parathyroid hormone
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
BR0107764A (pt) * 2000-01-20 2002-11-12 Basilea Pharmaceutica Ag Composições de peptìdeo cìclico nasalmente administráveis
US20030008005A1 (en) * 2001-07-05 2003-01-09 R.T. Alamo Ventures, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
GB2405334B (en) * 2002-04-17 2006-02-15 Nektar Therapeutics Uk Ltd Particulate materials
PL2425820T3 (pl) 2007-02-11 2015-08-31 Map Pharmaceuticals Inc Sposób terapeutycznego stosowania dhe w celu umożliwienia szybkiego złagodzenia migreny przy jednoczesnym zminimalizowaniu profilu działań niepożądanych
US20120000941A1 (en) * 2010-06-30 2012-01-05 Inspire Pharmaceuticals, Inc. Medicine dispenser
EP3049059B1 (en) 2013-09-24 2021-11-03 Satsuma Pharmaceuticals, Inc. Intranasal dhe formulation for the treatment of headache
EP3341059B1 (en) 2015-09-10 2022-03-02 Impel NeuroPharma Inc. In-line nasal delivery device
BR112019027508A2 (pt) * 2017-07-02 2020-07-07 Dr. Reddys Laboratories Limited formas de dosagem nasal de di-hidroergotamina
BR112020013744A8 (pt) 2018-01-05 2022-10-18 Impel Neuropharma Inc Dispensação intranasal de di-hidroergotamina por dispositivo olfativo de precisão
CA3122396A1 (en) 2018-12-11 2020-06-18 Satsuma Pharmaceuticals, Inc. Compositions, devices, and methods for treating or preventing headaches

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2351609A1 (de) * 1972-10-18 1974-04-25 Sandoz Ag Neue pharmazeutische zubereitungen

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1063512A (en) * 1962-11-30 1967-03-30 Benger Lab Ltd Aerosols
GB1175430A (en) * 1966-04-07 1969-12-23 Sandoz Ltd Pharmaceutical Compositions containing Ergot Alkaloids
CH507249A (de) * 1968-05-31 1971-05-15 Sandoz Ag Verfahren zur Herstellung von 2-Brom-a-ergokryptin
CH534683A (de) * 1970-05-26 1973-03-15 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
US4076715A (en) * 1972-09-26 1978-02-28 Sandoz Ltd. 13-Bromo lysergic acid compounds
CA990287A (en) * 1972-09-26 1976-06-01 Sandoz Patents Limited 13-bromo-lysergic acid compounds
US3896228A (en) * 1973-03-15 1975-07-22 Sandoz Ltd Method for treating nephrises
US3883655A (en) * 1973-10-11 1975-05-13 Sandoz Ltd Ergocornine or 2-bromo-{60 -ergocyptine in the treatment of parkinsonism
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
EP0119493A1 (en) * 1983-03-16 1984-09-26 American Cyanamid Company Use of copolymers of 2-acrylamido-2-methylpropane sulfonic acid for improving retention and dewatering in the manufacture of paper

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2351609A1 (de) * 1972-10-18 1974-04-25 Sandoz Ag Neue pharmazeutische zubereitungen

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FR-BSM 6823 M *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3302949A1 (de) * 1982-02-01 1983-08-11 Sandoz-Patent-GmbH, 7850 Lörrach Nasal verabreichbare pharmazeutische zusammensetzungen

Also Published As

Publication number Publication date
US4462983A (en) 1984-07-31
DK499477A (da) 1978-05-20
SG61784G (en) 1985-03-15
CA1103585A (en) 1981-06-23
CS228523B2 (en) 1984-05-14
IE46167L (en) 1978-05-19
ES464275A1 (es) 1978-12-16
PH23643A (en) 1989-09-27
DK153440B (da) 1988-07-18
FR2371454B1 (cg-RX-API-DMAC7.html) 1980-08-22
NL187892C (nl) 1992-02-17
JPS5366440A (en) 1978-06-13
DK153440C (da) 1989-01-02
SE451944B (sv) 1987-11-09
KE3453A (en) 1984-10-05
GB1592563A (en) 1981-07-08
MY8400055A (en) 1984-12-31
JPS6313965B2 (cg-RX-API-DMAC7.html) 1988-03-29
HK85984A (en) 1984-11-16
GR65229B (en) 1980-07-30
NZ185711A (en) 1980-04-28
NO773839L (no) 1978-05-22
AU520754B2 (en) 1982-02-25
ATA825477A (de) 1982-04-15
FR2371454A1 (fr) 1978-06-16
AT368881B (de) 1982-11-25
IL53419A (en) 1982-04-30
NL7712552A (nl) 1978-05-23
SE7712693L (sv) 1978-05-20
PT67292B (fr) 1979-11-12
NL187892B (nl) 1991-09-16
DE2802113A1 (de) 1979-07-26
US4758423A (en) 1988-07-19
AU3078377A (en) 1979-05-24
PT67292A (fr) 1977-12-01
HU185924B (en) 1985-03-28
FI773376A7 (fi) 1978-05-20
CY1266A (en) 1984-11-23
IL53419A0 (en) 1978-01-31
IE46167B1 (en) 1983-03-09
CS228502B2 (en) 1984-04-16

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection