DK153440C - Fremgangsmaade til fremstilling af et nasalt farmaceutisk ergotpeptidalkaloid-praeparat - Google Patents

Fremgangsmaade til fremstilling af et nasalt farmaceutisk ergotpeptidalkaloid-praeparat

Info

Publication number
DK153440C
DK153440C DK499477A DK499477A DK153440C DK 153440 C DK153440 C DK 153440C DK 499477 A DK499477 A DK 499477A DK 499477 A DK499477 A DK 499477A DK 153440 C DK153440 C DK 153440C
Authority
DK
Denmark
Prior art keywords
ergotpeptidalkaloid
preparing
procedure
preparation
national pharmaceutical
Prior art date
Application number
DK499477A
Other languages
English (en)
Other versions
DK499477A (da
DK153440B (da
Inventor
Moise Azria
Thomas Cavanak
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of DK499477A publication Critical patent/DK499477A/da
Publication of DK153440B publication Critical patent/DK153440B/da
Application granted granted Critical
Publication of DK153440C publication Critical patent/DK153440C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D2207/00—Indexing scheme relating to details of indicating measuring values
    • G01D2207/10—Displays which are primarily used in aircraft or display aircraft-specific information

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK499477A 1976-11-19 1977-11-10 Fremgangsmaade til fremstilling af et nasalt farmaceutisk ergotpeptidalkaloid-praeparat DK153440C (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH1457576 1976-11-19
CH1457576 1976-11-19
CH698977 1977-06-07
CH698977 1977-06-07

Publications (3)

Publication Number Publication Date
DK499477A DK499477A (da) 1978-05-20
DK153440B DK153440B (da) 1988-07-18
DK153440C true DK153440C (da) 1989-01-02

Family

ID=25700540

Family Applications (1)

Application Number Title Priority Date Filing Date
DK499477A DK153440C (da) 1976-11-19 1977-11-10 Fremgangsmaade til fremstilling af et nasalt farmaceutisk ergotpeptidalkaloid-praeparat

Country Status (27)

Country Link
US (2) US4462983A (da)
JP (1) JPS5366440A (da)
AT (1) AT368881B (da)
AU (1) AU520754B2 (da)
CA (1) CA1103585A (da)
CS (2) CS228502B2 (da)
CY (1) CY1266A (da)
DE (2) DE2750090A1 (da)
DK (1) DK153440C (da)
ES (1) ES464275A1 (da)
FI (1) FI773376A (da)
FR (1) FR2371454A1 (da)
GB (1) GB1592563A (da)
GR (1) GR65229B (da)
HK (1) HK85984A (da)
HU (1) HU185924B (da)
IE (1) IE46167B1 (da)
IL (1) IL53419A (da)
KE (1) KE3453A (da)
MY (1) MY8400055A (da)
NL (1) NL187892C (da)
NO (1) NO773839L (da)
NZ (1) NZ185711A (da)
PH (1) PH23643A (da)
PT (1) PT67292B (da)
SE (1) SE451944B (da)
SG (1) SG61784G (da)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
US4284648A (en) * 1979-08-03 1981-08-18 The University Of Kentucky Research Foundation Nasal administration of propranolol
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
FI81258C (fi) * 1982-02-01 1990-10-10 Sandoz Ag Foerfarande foer framstaellning av en farmaceutisk komposition foer nasal administration.
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
GB8413795D0 (en) * 1984-05-30 1984-07-04 Sandoz Ltd Organic compounds
GB8426922D0 (en) * 1984-10-24 1984-11-28 Sandoz Ltd Galenic formulation
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
FR2628638B1 (fr) * 1985-03-06 1992-12-18 Sandoz Lab Dispositif de pulverisation par voie nasale d'une dose unitaire de medicament en solution
JPS61263918A (ja) * 1985-05-16 1986-11-21 Banyu Pharmaceut Co Ltd 経皮吸収用製剤
EP0223831B1 (en) * 1985-05-22 1992-07-15 Liposome Technology, Inc. Liposome inhalation method and system
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
US4782047A (en) * 1986-05-22 1988-11-01 Syntex Pharmaceuticals International Ltd. Aqueous steroid formulations for nasal administration
US4897256A (en) * 1986-11-25 1990-01-30 Abbott Laboratories LHRH analog formulations
DE3710216A1 (de) * 1987-03-27 1988-10-06 Rentschler Arzneimittel Verwendung von dihydroergotamin und seinen salzen zur lokalen behandlung trophischer stoerungen
EP0338670B1 (en) * 1988-03-22 1994-05-11 FISONS plc Pharmaceutical Compositions
US4929640A (en) * 1988-04-04 1990-05-29 George D. McAdory Medicaments intended for combined use in the improvement of lymphocyte function
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
IT1247472B (it) * 1991-05-31 1994-12-17 Fidia Spa Processo per la preparazione di microsfere contenenti componenti biologicamente attivi.
AU660824B2 (en) * 1992-06-12 1995-07-06 Teijin Limited Pharmaceutical preparation for intra-airway administration
DE69332240T2 (de) * 1992-06-12 2003-04-10 Teijin Ltd Ultrafeines pulver zur inhalation und dessen herstellung
DK0865789T3 (da) * 1993-03-26 2005-07-18 Franciscus Wilhelmus He Merkus Farmaceutiske præparater til intranasal administration af dihydroergotamin
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
MX9704550A (es) 1994-12-22 1997-10-31 Astra Ab Formulaciones de medicamentos en aerosol.
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
SE9404468D0 (sv) * 1994-12-22 1994-12-22 Astra Ab Powder formulations
HU218940B (hu) * 1994-12-22 2001-01-29 Astra Aktiebolag Paratiroid hormont (PHT) tartalmazó, inhalációs célra szolgáló gyógyszerkészítmény, eljárás előállítására, alkalmazása inhalációs készülék töltésére és ezt tartalmazó inhalációs készülék
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
CA2396381A1 (en) * 2000-01-20 2001-07-26 Akira Yanagawa Nasally administrable cyclic peptide compositions
US20030008005A1 (en) * 2001-07-05 2003-01-09 R.T. Alamo Ventures, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
GB0208742D0 (en) * 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
GB2405334B (en) * 2002-04-17 2006-02-15 Nektar Therapeutics Uk Ltd Particulate materials
US8148377B2 (en) 2007-02-11 2012-04-03 Map Pharmaceuticals, Inc. Method of therapeutic administration of DHE to enable rapid relief of migraine while minimizing side effect profile
US20120000941A1 (en) * 2010-06-30 2012-01-05 Inspire Pharmaceuticals, Inc. Medicine dispenser
MX2018002895A (es) 2015-09-10 2018-07-06 Impel Neuropharma Inc Dispositivo de administracion nasal en linea.
BR112019027508A2 (pt) * 2017-07-02 2020-07-07 Dr. Reddys Laboratories Limited formas de dosagem nasal de di-hidroergotamina
AU2019205318B2 (en) 2018-01-05 2022-02-03 Impel Pharmaceuticals Inc. Intranasal delivery of dihydroergotamine by precision olfactory device
GB2581431A (en) * 2018-12-11 2020-08-19 Satsuma Pharmaceuticals Inc Compositions, devices, and methods for treating or preventing headaches
WO2020123607A1 (en) 2018-12-11 2020-06-18 Satsuma Pharmaceuticals, Inc. Compositions, devices, and methods for treating or preventing headaches

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1063512A (en) * 1962-11-30 1967-03-30 Benger Lab Ltd Aerosols
GB1175430A (en) * 1966-04-07 1969-12-23 Sandoz Ltd Pharmaceutical Compositions containing Ergot Alkaloids
CH507249A (de) * 1968-05-31 1971-05-15 Sandoz Ag Verfahren zur Herstellung von 2-Brom-a-ergokryptin
CH534683A (de) * 1970-05-26 1973-03-15 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
CA990287A (en) * 1972-09-26 1976-06-01 Sandoz Patents Limited 13-bromo-lysergic acid compounds
US4076715A (en) * 1972-09-26 1978-02-28 Sandoz Ltd. 13-Bromo lysergic acid compounds
NL7314066A (da) * 1972-10-18 1974-04-22
US3896228A (en) * 1973-03-15 1975-07-22 Sandoz Ltd Method for treating nephrises
US3883655A (en) * 1973-10-11 1975-05-13 Sandoz Ltd Ergocornine or 2-bromo-{60 -ergocyptine in the treatment of parkinsonism
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
EP0119493A1 (en) * 1983-03-16 1984-09-26 American Cyanamid Company Use of copolymers of 2-acrylamido-2-methylpropane sulfonic acid for improving retention and dewatering in the manufacture of paper

Also Published As

Publication number Publication date
PT67292B (fr) 1979-11-12
NO773839L (no) 1978-05-22
NL187892B (nl) 1991-09-16
NL187892C (nl) 1992-02-17
IL53419A0 (en) 1978-01-31
ES464275A1 (es) 1978-12-16
JPS5366440A (en) 1978-06-13
ATA825477A (de) 1982-04-15
AT368881B (de) 1982-11-25
US4462983A (en) 1984-07-31
AU3078377A (en) 1979-05-24
CA1103585A (en) 1981-06-23
SG61784G (en) 1985-03-15
GB1592563A (en) 1981-07-08
DK499477A (da) 1978-05-20
NL7712552A (nl) 1978-05-23
FR2371454A1 (fr) 1978-06-16
HK85984A (en) 1984-11-16
PT67292A (fr) 1977-12-01
CY1266A (en) 1984-11-23
IE46167L (en) 1978-05-19
DE2750090A1 (de) 1978-06-01
HU185924B (en) 1985-03-28
CS228502B2 (en) 1984-04-16
PH23643A (en) 1989-09-27
SE451944B (sv) 1987-11-09
FR2371454B1 (da) 1980-08-22
KE3453A (en) 1984-10-05
AU520754B2 (en) 1982-02-25
US4758423A (en) 1988-07-19
MY8400055A (en) 1984-12-31
CS228523B2 (en) 1984-05-14
DE2802113A1 (de) 1979-07-26
IE46167B1 (en) 1983-03-09
NZ185711A (en) 1980-04-28
IL53419A (en) 1982-04-30
SE7712693L (sv) 1978-05-20
JPS6313965B2 (da) 1988-03-29
GR65229B (en) 1980-07-30
DK153440B (da) 1988-07-18
FI773376A (fi) 1978-05-20

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Legal Events

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PUP Patent expired