NL7712552A - Werkwijzen voor het bereiden en toepassen van ergot peptidealkaloiden. - Google Patents

Werkwijzen voor het bereiden en toepassen van ergot peptidealkaloiden.

Info

Publication number
NL7712552A
NL7712552A NL7712552A NL7712552A NL7712552A NL 7712552 A NL7712552 A NL 7712552A NL 7712552 A NL7712552 A NL 7712552A NL 7712552 A NL7712552 A NL 7712552A NL 7712552 A NL7712552 A NL 7712552A
Authority
NL
Netherlands
Prior art keywords
peptideal
caloids
ergot
preparing
methods
Prior art date
Application number
NL7712552A
Other languages
English (en)
Other versions
NL187892B (nl
NL187892C (nl
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NL7712552A publication Critical patent/NL7712552A/nl
Publication of NL187892B publication Critical patent/NL187892B/nl
Application granted granted Critical
Publication of NL187892C publication Critical patent/NL187892C/nl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D2207/00—Indexing scheme relating to details of indicating measuring values
    • G01D2207/10—Displays which are primarily used in aircraft or display aircraft-specific information

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NLAANVRAGE7712552,A 1976-11-19 1977-11-15 Werkwijze voor het bereiden of vervaardigen van een farmaceutisch preparaat, dat een dihydroergotoxine bevat, alsmede inrichting voor het via de neus toedienen van een farmaceutisch preparaat. NL187892C (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1457576 1976-11-19
CH698977 1977-06-07

Publications (3)

Publication Number Publication Date
NL7712552A true NL7712552A (nl) 1978-05-23
NL187892B NL187892B (nl) 1991-09-16
NL187892C NL187892C (nl) 1992-02-17

Family

ID=25700540

Family Applications (1)

Application Number Title Priority Date Filing Date
NLAANVRAGE7712552,A NL187892C (nl) 1976-11-19 1977-11-15 Werkwijze voor het bereiden of vervaardigen van een farmaceutisch preparaat, dat een dihydroergotoxine bevat, alsmede inrichting voor het via de neus toedienen van een farmaceutisch preparaat.

Country Status (27)

Country Link
US (2) US4462983A (nl)
JP (1) JPS5366440A (nl)
AT (1) AT368881B (nl)
AU (1) AU520754B2 (nl)
CA (1) CA1103585A (nl)
CS (2) CS228523B2 (nl)
CY (1) CY1266A (nl)
DE (2) DE2750090A1 (nl)
DK (1) DK153440C (nl)
ES (1) ES464275A1 (nl)
FI (1) FI773376A (nl)
FR (1) FR2371454A1 (nl)
GB (1) GB1592563A (nl)
GR (1) GR65229B (nl)
HK (1) HK85984A (nl)
HU (1) HU185924B (nl)
IE (1) IE46167B1 (nl)
IL (1) IL53419A (nl)
KE (1) KE3453A (nl)
MY (1) MY8400055A (nl)
NL (1) NL187892C (nl)
NO (1) NO773839L (nl)
NZ (1) NZ185711A (nl)
PH (1) PH23643A (nl)
PT (1) PT67292B (nl)
SE (1) SE451944B (nl)
SG (1) SG61784G (nl)

Families Citing this family (43)

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Publication number Priority date Publication date Assignee Title
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
US4284648A (en) * 1979-08-03 1981-08-18 The University Of Kentucky Research Foundation Nasal administration of propranolol
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
FI81258C (fi) * 1982-02-01 1990-10-10 Sandoz Ag Foerfarande foer framstaellning av en farmaceutisk komposition foer nasal administration.
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
GB8413795D0 (en) * 1984-05-30 1984-07-04 Sandoz Ltd Organic compounds
GB8426922D0 (en) * 1984-10-24 1984-11-28 Sandoz Ltd Galenic formulation
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
FR2628638B1 (fr) * 1985-03-06 1992-12-18 Sandoz Lab Dispositif de pulverisation par voie nasale d'une dose unitaire de medicament en solution
JPS61263918A (ja) * 1985-05-16 1986-11-21 Banyu Pharmaceut Co Ltd 経皮吸収用製剤
AU587472B2 (en) * 1985-05-22 1989-08-17 Liposome Technology, Inc. Liposome inhalation method and system
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
US4782047A (en) * 1986-05-22 1988-11-01 Syntex Pharmaceuticals International Ltd. Aqueous steroid formulations for nasal administration
US4897256A (en) * 1986-11-25 1990-01-30 Abbott Laboratories LHRH analog formulations
DE3710216A1 (de) * 1987-03-27 1988-10-06 Rentschler Arzneimittel Verwendung von dihydroergotamin und seinen salzen zur lokalen behandlung trophischer stoerungen
DE68915203T2 (de) * 1988-03-22 1994-09-22 Fisons Plc Pharmazeutische Mischungen.
US4929640A (en) * 1988-04-04 1990-05-29 George D. McAdory Medicaments intended for combined use in the improvement of lymphocyte function
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
IT1247472B (it) * 1991-05-31 1994-12-17 Fidia Spa Processo per la preparazione di microsfere contenenti componenti biologicamente attivi.
KR100208979B1 (ko) * 1992-06-12 1999-07-15 야스이 쇼사꾸 기도내 투여용 제제
ES2177544T3 (es) * 1992-06-12 2002-12-16 Teijin Ltd Polvo ultrafinno para inhalar y metodo para su preparacion.
US5756483A (en) * 1993-03-26 1998-05-26 Merkus; Franciscus W. H. M. Pharmaceutical compositions for intranasal administration of apomorphine
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
US6794357B1 (en) * 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
KR100389080B1 (ko) * 1994-12-22 2003-10-17 아스트라제네카 악티에볼라그 부갑상선호르몬(pth)을포함하는흡입용치료제제
SE9404468D0 (sv) * 1994-12-22 1994-12-22 Astra Ab Powder formulations
CZ288146B6 (en) 1994-12-22 2001-05-16 Astra Ab Pharmaceutical aerosol preparation, process of its preparation and use
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
CA2396381A1 (en) * 2000-01-20 2001-07-26 Akira Yanagawa Nasally administrable cyclic peptide compositions
US20030008005A1 (en) * 2001-07-05 2003-01-09 R.T. Alamo Ventures, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
GB2405334B (en) * 2002-04-17 2006-02-15 Nektar Therapeutics Uk Ltd Particulate materials
EP2425820B1 (en) 2007-02-11 2015-04-08 MAP Pharmaceuticals Inc Method of therapeutic administration of dhe to enable rapid relief of migraine while minimizing side effect profile
US20120000941A1 (en) * 2010-06-30 2012-01-05 Inspire Pharmaceuticals, Inc. Medicine dispenser
MX2018002895A (es) 2015-09-10 2018-07-06 Impel Neuropharma Inc Dispositivo de administracion nasal en linea.
UA126201C2 (uk) * 2017-07-02 2022-08-31 Др. Редді'С Лабораторіз Лтд. Назальна дозована лікарська форма дигідроерготаміну
US20190209463A1 (en) 2018-01-05 2019-07-11 Impel Neuropharma, Inc. Intranasal delivery of dihydroergotamine by precision olfactory device
GB2581431A (en) * 2018-12-11 2020-08-19 Satsuma Pharmaceuticals Inc Compositions, devices, and methods for treating or preventing headaches
US10758532B2 (en) 2018-12-11 2020-09-01 Satsuma Pharmaceuticals, Inc. Compositions, devices, and methods for treating or preventing headaches

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1063512A (en) * 1962-11-30 1967-03-30 Benger Lab Ltd Aerosols
GB1175430A (en) * 1966-04-07 1969-12-23 Sandoz Ltd Pharmaceutical Compositions containing Ergot Alkaloids
CH507249A (de) * 1968-05-31 1971-05-15 Sandoz Ag Verfahren zur Herstellung von 2-Brom-a-ergokryptin
CH534683A (de) * 1970-05-26 1973-03-15 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
CA990287A (en) * 1972-09-26 1976-06-01 Sandoz Patents Limited 13-bromo-lysergic acid compounds
US4076715A (en) * 1972-09-26 1978-02-28 Sandoz Ltd. 13-Bromo lysergic acid compounds
NL7314066A (nl) * 1972-10-18 1974-04-22
US3896228A (en) * 1973-03-15 1975-07-22 Sandoz Ltd Method for treating nephrises
US3883655A (en) * 1973-10-11 1975-05-13 Sandoz Ltd Ergocornine or 2-bromo-{60 -ergocyptine in the treatment of parkinsonism
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
EP0119493A1 (en) * 1983-03-16 1984-09-26 American Cyanamid Company Use of copolymers of 2-acrylamido-2-methylpropane sulfonic acid for improving retention and dewatering in the manufacture of paper

Also Published As

Publication number Publication date
US4462983A (en) 1984-07-31
GR65229B (en) 1980-07-30
DK153440C (da) 1989-01-02
DK499477A (da) 1978-05-20
GB1592563A (en) 1981-07-08
PH23643A (en) 1989-09-27
DE2802113A1 (de) 1979-07-26
AT368881B (de) 1982-11-25
PT67292A (fr) 1977-12-01
SG61784G (en) 1985-03-15
FR2371454A1 (fr) 1978-06-16
ES464275A1 (es) 1978-12-16
MY8400055A (en) 1984-12-31
SE7712693L (sv) 1978-05-20
US4758423A (en) 1988-07-19
CY1266A (en) 1984-11-23
DE2750090A1 (de) 1978-06-01
DK153440B (da) 1988-07-18
SE451944B (sv) 1987-11-09
KE3453A (en) 1984-10-05
NL187892B (nl) 1991-09-16
CS228523B2 (en) 1984-05-14
IE46167B1 (en) 1983-03-09
IL53419A0 (en) 1978-01-31
JPS5366440A (en) 1978-06-13
JPS6313965B2 (nl) 1988-03-29
AU520754B2 (en) 1982-02-25
NL187892C (nl) 1992-02-17
ATA825477A (de) 1982-04-15
HU185924B (en) 1985-03-28
HK85984A (en) 1984-11-16
IE46167L (en) 1978-05-19
IL53419A (en) 1982-04-30
FI773376A (fi) 1978-05-20
NZ185711A (en) 1980-04-28
PT67292B (fr) 1979-11-12
NO773839L (no) 1978-05-22
CS228502B2 (en) 1984-04-16
AU3078377A (en) 1979-05-24
FR2371454B1 (nl) 1980-08-22
CA1103585A (en) 1981-06-23

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Legal Events

Date Code Title Description
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
A85 Still pending on 85-01-01
V4 Discontinued because of reaching the maximum lifetime of a patent

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