AT368881B - Verfahren zur herstellung einer nasalen verabreichungsform fuer organische verbindungen - Google Patents

Verfahren zur herstellung einer nasalen verabreichungsform fuer organische verbindungen

Info

Publication number
AT368881B
AT368881B AT0825477A AT825477A AT368881B AT 368881 B AT368881 B AT 368881B AT 0825477 A AT0825477 A AT 0825477A AT 825477 A AT825477 A AT 825477A AT 368881 B AT368881 B AT 368881B
Authority
AT
Austria
Prior art keywords
nasal
producing
organic compounds
administrative form
administrative
Prior art date
Application number
AT0825477A
Other languages
English (en)
Other versions
ATA825477A (de
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of ATA825477A publication Critical patent/ATA825477A/de
Application granted granted Critical
Publication of AT368881B publication Critical patent/AT368881B/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01D—MEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D2207/00—Indexing scheme relating to details of indicating measuring values
    • G01D2207/10—Displays which are primarily used in aircraft or display aircraft-specific information

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT0825477A 1976-11-19 1977-11-18 Verfahren zur herstellung einer nasalen verabreichungsform fuer organische verbindungen AT368881B (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1457576 1976-11-19
CH698977 1977-06-07

Publications (2)

Publication Number Publication Date
ATA825477A ATA825477A (de) 1982-04-15
AT368881B true AT368881B (de) 1982-11-25

Family

ID=25700540

Family Applications (1)

Application Number Title Priority Date Filing Date
AT0825477A AT368881B (de) 1976-11-19 1977-11-18 Verfahren zur herstellung einer nasalen verabreichungsform fuer organische verbindungen

Country Status (27)

Country Link
US (2) US4462983A (de)
JP (1) JPS5366440A (de)
AT (1) AT368881B (de)
AU (1) AU520754B2 (de)
CA (1) CA1103585A (de)
CS (2) CS228502B2 (de)
CY (1) CY1266A (de)
DE (2) DE2750090A1 (de)
DK (1) DK153440C (de)
ES (1) ES464275A1 (de)
FI (1) FI773376A (de)
FR (1) FR2371454A1 (de)
GB (1) GB1592563A (de)
GR (1) GR65229B (de)
HK (1) HK85984A (de)
HU (1) HU185924B (de)
IE (1) IE46167B1 (de)
IL (1) IL53419A (de)
KE (1) KE3453A (de)
MY (1) MY8400055A (de)
NL (1) NL187892C (de)
NO (1) NO773839L (de)
NZ (1) NZ185711A (de)
PH (1) PH23643A (de)
PT (1) PT67292B (de)
SE (1) SE451944B (de)
SG (1) SG61784G (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
US4284648A (en) * 1979-08-03 1981-08-18 The University Of Kentucky Research Foundation Nasal administration of propranolol
CH649300A5 (de) * 1981-08-07 1985-05-15 Sandoz Ag Ergopeptinderivate, ihre herstellung und verwendung.
FI81258C (fi) * 1982-02-01 1990-10-10 Sandoz Ag Foerfarande foer framstaellning av en farmaceutisk komposition foer nasal administration.
GB8301659D0 (en) * 1983-01-21 1983-02-23 Leo Ab Smoking substitutes
GB8413795D0 (en) * 1984-05-30 1984-07-04 Sandoz Ltd Organic compounds
GB8426922D0 (en) * 1984-10-24 1984-11-28 Sandoz Ltd Galenic formulation
GB8501015D0 (en) * 1985-01-16 1985-02-20 Riker Laboratories Inc Drug
FR2628638B1 (fr) * 1985-03-06 1992-12-18 Sandoz Lab Dispositif de pulverisation par voie nasale d'une dose unitaire de medicament en solution
JPS61263918A (ja) * 1985-05-16 1986-11-21 Banyu Pharmaceut Co Ltd 経皮吸収用製剤
EP0223831B1 (de) * 1985-05-22 1992-07-15 Liposome Technology, Inc. Verfahren und system zum einatmen von liposomen
CA1291036C (en) * 1986-04-23 1991-10-22 Edwin I. Stoltz Nasal administration of drugs
US4782047A (en) * 1986-05-22 1988-11-01 Syntex Pharmaceuticals International Ltd. Aqueous steroid formulations for nasal administration
US4897256A (en) * 1986-11-25 1990-01-30 Abbott Laboratories LHRH analog formulations
DE3710216A1 (de) * 1987-03-27 1988-10-06 Rentschler Arzneimittel Verwendung von dihydroergotamin und seinen salzen zur lokalen behandlung trophischer stoerungen
EP0338670B1 (de) * 1988-03-22 1994-05-11 FISONS plc Pharmazeutische Mischungen
US4929640A (en) * 1988-04-04 1990-05-29 George D. McAdory Medicaments intended for combined use in the improvement of lymphocyte function
GB2237510B (en) * 1989-11-04 1993-09-15 Danbiosyst Uk Small particle drug compositions for nasal administration
IT1247472B (it) * 1991-05-31 1994-12-17 Fidia Spa Processo per la preparazione di microsfere contenenti componenti biologicamente attivi.
KR100277622B1 (ko) * 1992-06-12 2001-01-15 이타가키 히로시 흡입용 초미립자 분말 및 그의 제조방법
EP0606486B1 (de) * 1992-06-12 2001-08-29 Teijin Limited Pharmazeutische zubereitung zur anwendung in den atemwegen
JPH08508472A (ja) * 1993-03-26 1996-09-10 ダブリュー．エイチ．エム． マーカス フランシスカス ジヒドロエルゴタミン、アポモルヒネ及びモルヒネを鼻腔内へ投与するための薬剤
US6794357B1 (en) 1993-06-24 2004-09-21 Astrazeneca Ab Compositions for inhalation
US6632456B1 (en) 1993-06-24 2003-10-14 Astrazeneca Ab Compositions for inhalation
US5830853A (en) 1994-06-23 1998-11-03 Astra Aktiebolag Systemic administration of a therapeutic preparation
US20010003739A1 (en) * 1993-06-24 2001-06-14 Astrazeneca Ab Systemic administration of a therapeutic preparation
US6524557B1 (en) * 1994-12-22 2003-02-25 Astrazeneca Ab Aerosol formulations of peptides and proteins
ES2197212T3 (es) * 1994-12-22 2004-01-01 Astrazeneca Ab Preparacion terapeutica para inhalacion que contiene la hormona paratiroidea, pth.
SE9404468D0 (sv) * 1994-12-22 1994-12-22 Astra Ab Powder formulations
ATE236617T1 (de) 1994-12-22 2003-04-15 Astrazeneca Ab Aerosol-arzneiformulierungen
US5955098A (en) * 1996-04-12 1999-09-21 Flemington Pharmaceutical Corp. Buccal non polar spray or capsule
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
KR20020070346A (ko) * 2000-01-20 2002-09-05 바실리어 파마슈티카 아게 비강 투여 가능 고리형 펩티드 조성물
US20030008005A1 (en) * 2001-07-05 2003-01-09 R.T. Alamo Ventures, Inc. Sublingual administration of dihydroergotamine for the treatment of migraine
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
GB2405334B (en) * 2002-04-17 2006-02-15 Nektar Therapeutics Uk Ltd Particulate materials
ES2538082T3 (es) * 2007-02-11 2015-06-17 Map Pharmaceuticals Inc Método de administración terapéutica de DHE para permitir el rápido alivio de migraña mientras que se minimiza el perfil de efectos secundarios
US20120000941A1 (en) * 2010-06-30 2012-01-05 Inspire Pharmaceuticals, Inc. Medicine dispenser
US11266799B2 (en) 2015-09-10 2022-03-08 Impel Neuropharma, Inc. In-line nasal delivery device
UA126201C2 (uk) * 2017-07-02 2022-08-31 Др. Редді'С Лабораторіз Лтд. Назальна дозована лікарська форма дигідроерготаміну
BR112020013744A8 (pt) 2018-01-05 2022-10-18 Impel Neuropharma Inc Dispensação intranasal de di-hidroergotamina por dispositivo olfativo de precisão
CA3122396A1 (en) 2018-12-11 2020-06-18 Satsuma Pharmaceuticals, Inc. Compositions, devices, and methods for treating or preventing headaches
GB2581431A (en) * 2018-12-11 2020-08-19 Satsuma Pharmaceuticals Inc Compositions, devices, and methods for treating or preventing headaches

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1063512A (en) * 1962-11-30 1967-03-30 Benger Lab Ltd Aerosols
GB1175430A (en) * 1966-04-07 1969-12-23 Sandoz Ltd Pharmaceutical Compositions containing Ergot Alkaloids
CH507249A (de) * 1968-05-31 1971-05-15 Sandoz Ag Verfahren zur Herstellung von 2-Brom-a-ergokryptin
CH534683A (de) * 1970-05-26 1973-03-15 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
CA990287A (en) * 1972-09-26 1976-06-01 Sandoz Patents Limited 13-bromo-lysergic acid compounds
US4076715A (en) * 1972-09-26 1978-02-28 Sandoz Ltd. 13-Bromo lysergic acid compounds
NL7314066A (de) * 1972-10-18 1974-04-22
US3896228A (en) * 1973-03-15 1975-07-22 Sandoz Ltd Method for treating nephrises
US3883655A (en) * 1973-10-11 1975-05-13 Sandoz Ltd Ergocornine or 2-bromo-{60 -ergocyptine in the treatment of parkinsonism
DE2750090A1 (de) * 1976-11-19 1978-06-01 Sandoz Ag Neue verabreichungsformen fuer organische verbindungen
EP0119493A1 (de) * 1983-03-16 1984-09-26 American Cyanamid Company Verwendung von Copolymeren der 2-Acrylamido-2-Methylpropan-Sulfonsäure zur Verbesserung des Zurückhaltevermögens und der Entwässerung in der Papierherstellung

Also Published As

Publication number Publication date
CS228502B2 (en) 1984-04-16
DK499477A (da) 1978-05-20
NO773839L (no) 1978-05-22
ES464275A1 (es) 1978-12-16
IL53419A (en) 1982-04-30
DE2802113A1 (de) 1979-07-26
JPS6313965B2 (de) 1988-03-29
NL7712552A (nl) 1978-05-23
HU185924B (en) 1985-03-28
ATA825477A (de) 1982-04-15
US4758423A (en) 1988-07-19
NZ185711A (en) 1980-04-28
PT67292A (fr) 1977-12-01
IE46167L (en) 1978-05-19
NL187892B (nl) 1991-09-16
DE2750090A1 (de) 1978-06-01
US4462983A (en) 1984-07-31
HK85984A (en) 1984-11-16
SE7712693L (sv) 1978-05-20
PH23643A (en) 1989-09-27
SE451944B (sv) 1987-11-09
JPS5366440A (en) 1978-06-13
FI773376A (fi) 1978-05-20
MY8400055A (en) 1984-12-31
CA1103585A (en) 1981-06-23
FR2371454B1 (de) 1980-08-22
NL187892C (nl) 1992-02-17
KE3453A (en) 1984-10-05
IE46167B1 (en) 1983-03-09
DK153440B (da) 1988-07-18
GB1592563A (en) 1981-07-08
GR65229B (en) 1980-07-30
CY1266A (en) 1984-11-23
DK153440C (da) 1989-01-02
AU3078377A (en) 1979-05-24
PT67292B (fr) 1979-11-12
FR2371454A1 (fr) 1978-06-16
IL53419A0 (en) 1978-01-31
SG61784G (en) 1985-03-15
AU520754B2 (en) 1982-02-25
CS228523B2 (en) 1984-05-14

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