ES2194867T3 - Composiciones farmaceuticas para la administracion intranasal de apomorfina. - Google Patents
Composiciones farmaceuticas para la administracion intranasal de apomorfina.Info
- Publication number
- ES2194867T3 ES2194867T3 ES94911944T ES94911944T ES2194867T3 ES 2194867 T3 ES2194867 T3 ES 2194867T3 ES 94911944 T ES94911944 T ES 94911944T ES 94911944 T ES94911944 T ES 94911944T ES 2194867 T3 ES2194867 T3 ES 2194867T3
- Authority
- ES
- Spain
- Prior art keywords
- apomorphine
- pharmaceutical compositions
- intranasal administration
- dihydroergotaminesalt
- dihydroergotamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/40—Cyclodextrins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
Abstract
LA INVENCION SE REFIERE A COMPOSICIONES FARMACEUTICAS PARA LA ADMINISTRACION INTRANASAL DE DIHIDROERGOTAMINA, APOMORFINA Y MORFINA QUE COMPRENDEN UNO DE ESTOS INGREDIENTES FARMACOLOGICAMENTE ACTIVOS EN COMBINACION CON CITODEXTRINA Y/O UN DISACARIDO, Y/O UN POLISACARIDO Y/O UN ALCOHOL DE AZUCAR.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
BE9300298A BE1006871A6 (nl) | 1993-03-26 | 1993-03-26 | Nasale farmaceutische preparaten met apomorfine. |
BE9300299A BE1006872A6 (nl) | 1993-03-26 | 1993-03-26 | Nasale farmaceutische preparaten met dihydroergotamine (dhe). |
BE9300297A BE1006870A6 (nl) | 1993-03-26 | 1993-03-26 | Nasale farmaceutische preparaten met morfine. |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2194867T3 true ES2194867T3 (es) | 2003-12-01 |
Family
ID=27159799
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98109002T Expired - Lifetime ES2239369T3 (es) | 1993-03-26 | 1994-03-18 | Composiciones farmaceuticas para administracion intranasal de dihidroergotamina. |
ES94911944T Expired - Lifetime ES2194867T3 (es) | 1993-03-26 | 1994-03-18 | Composiciones farmaceuticas para la administracion intranasal de apomorfina. |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES98109002T Expired - Lifetime ES2239369T3 (es) | 1993-03-26 | 1994-03-18 | Composiciones farmaceuticas para administracion intranasal de dihidroergotamina. |
Country Status (10)
Country | Link |
---|---|
US (2) | US5756483A (es) |
EP (2) | EP0689438B1 (es) |
JP (2) | JPH08508472A (es) |
AT (2) | ATE241984T1 (es) |
AU (1) | AU6428894A (es) |
DE (2) | DE69432789T2 (es) |
DK (2) | DK0865789T3 (es) |
ES (2) | ES2239369T3 (es) |
PT (2) | PT689438E (es) |
WO (1) | WO1994022445A2 (es) |
Families Citing this family (98)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10199068I2 (de) * | 1994-04-22 | 2004-05-06 | Pentech Pharmaceuticals Inc | Sublinguale Dosierungsformen enthaltend apomorphinzur Verwendung bei der Behandlung von erektiler D ysfunktion. |
US6121276A (en) * | 1994-04-22 | 2000-09-19 | Pentech Pharmaceuticals, Inc. | Apomorphine-containing dosage forms for ameliorating male erectile dysfunction |
US6395744B1 (en) | 1994-04-22 | 2002-05-28 | Queen's University At Kingston | Method and compositions for the treatment or amelioration of female sexual dysfunction |
US5612053A (en) | 1995-04-07 | 1997-03-18 | Edward Mendell Co., Inc. | Controlled release insufflation carrier for medicaments |
JPH11503750A (ja) * | 1995-04-17 | 1999-03-30 | サンチェズ,ロバート | ウルシオールの錯体化 |
GB9517062D0 (en) * | 1995-08-18 | 1995-10-25 | Scherer Ltd R P | Pharmaceutical compositions |
US6017963A (en) * | 1995-11-14 | 2000-01-25 | Euro-Celtique, S.A. | Formulation for intranasal administration |
EP0834308A1 (en) * | 1996-09-30 | 1998-04-08 | LG Chemical Limited | Ophthalmic formulation for treating myopia comprising dopamine agonist and cyclodextrin |
US5855907A (en) * | 1997-03-24 | 1999-01-05 | Peyman; Gholam A. | Method of treatment of migraine |
US8631796B2 (en) | 1997-04-10 | 2014-01-21 | Cookgas, L.L.C. | Laryngeal mask |
EP1035833B1 (en) * | 1997-12-02 | 2005-08-31 | Archimedes Development Limited | Compositions for nasal administration |
PT1051155E (pt) * | 1998-01-30 | 2002-10-31 | Novartis Consumer Health Sa | Solucoes nasais |
US6403605B1 (en) | 1998-05-29 | 2002-06-11 | Queen's University At Kingston | Methods for the normalization of sexual response and amelioration of long term genital tissue degradation |
US20020002175A1 (en) * | 2000-09-19 | 2002-01-03 | Charanjit Behl | Nasal delivery of apomorphine in combination with glycol derivatives |
US6436950B1 (en) * | 1998-08-14 | 2002-08-20 | Nastech Pharmaceutical Company, Inc. | Nasal delivery of apomorphine |
CA2346656A1 (en) * | 1998-10-20 | 2000-04-27 | The University Of North Carolina At Chapel Hill | Methods of hydrating mucosal surfaces |
US6291471B1 (en) | 1998-12-17 | 2001-09-18 | Abb Holdings, Inc. | Use of apomorphine for the treatment of organic erectile dysfunction in males |
US6225343B1 (en) | 1999-06-16 | 2001-05-01 | Nastech Pharmaceutical Company, Inc. | Compositions and methods comprising morphine gluconate |
ES2197792B1 (es) * | 1999-06-16 | 2005-05-01 | Nastech Pharmaceutical Co., Inc. | Formulaciones farmaceuticas que contienen morfina intranasal. |
GB9924797D0 (en) | 1999-10-20 | 1999-12-22 | West Pharm Serv Drug Res Ltd | Compound |
IL150034A0 (en) * | 1999-12-30 | 2002-12-01 | Tap Holdings Inc | Oral mucosal dosage forms of apomorphine |
BR0109515A (pt) | 2000-04-07 | 2004-08-10 | Tap Pharmaceutical Prod Inc | Derivados da apomorfina e métodos para seu uso |
US20020013331A1 (en) * | 2000-06-26 | 2002-01-31 | Williams Robert O. | Methods and compositions for treating pain of the mucous membrane |
DE10041478A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
CA2429047A1 (en) | 2000-11-15 | 2002-05-23 | Tap Pharmaceutical Products, Inc. | Treatment of anti-depression drug-induced sexual dysfunction with apomorphine |
US20030027793A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal treatment of parkinson's disease |
US20030026830A1 (en) * | 2001-05-08 | 2003-02-06 | Thomas Lauterback | Transdermal therapeutic system for parkinson's disease inducing high plasma levels of rotigotine |
US20030017175A1 (en) * | 2001-07-05 | 2003-01-23 | R.T. Alamo Ventures I, Inc. | Sublingual administration of dihydroergotamine for the treatment of migraine |
US20030198669A1 (en) * | 2001-07-05 | 2003-10-23 | R.T. Alamo Ventures I, Llc | Compositions and methods for rapid dissolving formulations of dihydroergotamine and caffeine for the treatment of migraine |
US6685951B2 (en) | 2001-07-05 | 2004-02-03 | R. T. Alamo Ventures I, Inc. | Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine |
US20030187011A1 (en) * | 2001-12-20 | 2003-10-02 | Lashuel Hilal A. | Apomorphine inhibitors of amyloid-beta (Abeta) fibril formation and their use in amyloidosis based disease |
US7666876B2 (en) * | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
BR0308567A (pt) * | 2002-03-19 | 2007-01-09 | Michael Holick | derivados de glicosìdeo e glicosìdeo de ortoéster de apomorfina, análogos, e seus usos |
EP1355158A1 (de) * | 2002-04-19 | 2003-10-22 | B.R.A.H.M.S Aktiengesellschaft | Verfahren zur Diagnose von Entzündungserkrankungen und Infektionen unter Bestimmung des Phosphoproteins LASP-1 als Inflammationsmarker |
US20040048779A1 (en) * | 2002-05-06 | 2004-03-11 | Erwin Schollmayer | Use of rotigotine for treating the restless leg syndrome |
US7736665B2 (en) * | 2002-05-31 | 2010-06-15 | Titan Pharmaceuticals, Inc. | Implantable polymeric device for sustained release of buprenorphine |
US8557291B2 (en) * | 2002-07-05 | 2013-10-15 | Collegium Pharmaceutical, Inc. | Abuse-deterrent pharmaceutical compositions of opioids and other drugs |
JP4694207B2 (ja) | 2002-07-05 | 2011-06-08 | コルジウム ファーマシューティカル, インコーポレイテッド | オピオイドおよび他の薬物に関する乱用抑止性の薬学的組成物 |
US10004729B2 (en) | 2002-07-05 | 2018-06-26 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
US8840928B2 (en) * | 2002-07-05 | 2014-09-23 | Collegium Pharmaceutical, Inc. | Tamper-resistant pharmaceutical compositions of opioids and other drugs |
GB0300531D0 (en) | 2003-01-10 | 2003-02-12 | West Pharm Serv Drug Res Ltd | Pharmaceutical compositions |
WO2004073729A1 (ja) | 2003-02-21 | 2004-09-02 | Translational Research Ltd. | 薬物の経鼻投与用組成物 |
GB0304636D0 (en) * | 2003-02-28 | 2003-04-02 | Britannia Pharmaceuticals Ltd | Pharmaceutical composition for nasal delivery |
AU2003220808B2 (en) | 2003-03-27 | 2008-08-21 | Bioactis Limited | Powder medicine applicator for nasal cavity |
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US20050090518A1 (en) * | 2003-10-24 | 2005-04-28 | Nastech Pharmaceutical Company Inc. | Method for treating parkinson's disease using apomorphine and apomorphine prodrugs |
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US20110111014A1 (en) * | 2007-06-26 | 2011-05-12 | Parkinson's Institute | Methods and compositions for treatment of neurological disorders |
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WO2009040595A1 (en) * | 2007-09-28 | 2009-04-02 | Wockhardt Research Centre | Multi-dose pharmaceutical composition of analgesic for nasal administration |
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CA2784207C (en) * | 2009-12-14 | 2018-06-05 | Chiesi Farmaceutici S.P.A. | Antibiotic microparticles for inhalation |
TW201304822A (zh) | 2010-11-15 | 2013-02-01 | Vectura Ltd | 組成物及用途 |
EP2545905A1 (en) * | 2011-07-11 | 2013-01-16 | Britannia Pharmaceuticals Limited | A new therapeutical composition containing apomorphine as active ingredient |
EP2877178A1 (en) | 2012-07-26 | 2015-06-03 | Wockhardt Limited | Pharmaceutical composition comprising diamorphine for intranasal administration |
CA2895816C (en) | 2012-12-21 | 2021-02-23 | Map Pharmaceuticals, Inc. | 8'-hydroxy-dihydroergotamine compounds and compositions |
DK3049059T3 (da) * | 2013-09-24 | 2022-01-31 | Satsuma Pharmaceuticals Inc | Intranasal dhe formulering til behandlingen af hovedpine |
IL257845B (en) | 2015-09-10 | 2022-07-01 | Impel Neuropharma Inc | Lined nasal delivery device |
US9737530B1 (en) | 2016-06-23 | 2017-08-22 | Collegium Pharmaceutical, Inc. | Process of making stable abuse-deterrent oral formulations |
US11744967B2 (en) | 2017-09-26 | 2023-09-05 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal delivery devices |
BR112020013744A8 (pt) * | 2018-01-05 | 2022-10-18 | Impel Neuropharma Inc | Dispensação intranasal de di-hidroergotamina por dispositivo olfativo de precisão |
GB2581431A (en) * | 2018-12-11 | 2020-08-19 | Satsuma Pharmaceuticals Inc | Compositions, devices, and methods for treating or preventing headaches |
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1994
- 1994-03-18 PT PT94911944T patent/PT689438E/pt unknown
- 1994-03-18 PT PT98109002T patent/PT865789E/pt unknown
- 1994-03-18 JP JP6521631A patent/JPH08508472A/ja active Pending
- 1994-03-18 AU AU64288/94A patent/AU6428894A/en not_active Abandoned
- 1994-03-18 DE DE69432789T patent/DE69432789T2/de not_active Expired - Lifetime
- 1994-03-18 DK DK98109002T patent/DK0865789T3/da active
- 1994-03-18 ES ES98109002T patent/ES2239369T3/es not_active Expired - Lifetime
- 1994-03-18 AT AT94911944T patent/ATE241984T1/de active
- 1994-03-18 EP EP94911944A patent/EP0689438B1/en not_active Expired - Lifetime
- 1994-03-18 AT AT98109002T patent/ATE290864T1/de active
- 1994-03-18 ES ES94911944T patent/ES2194867T3/es not_active Expired - Lifetime
- 1994-03-18 EP EP98109002A patent/EP0865789B1/en not_active Expired - Lifetime
- 1994-03-18 DE DE69434304T patent/DE69434304T2/de not_active Expired - Lifetime
- 1994-03-18 DK DK94911944T patent/DK0689438T3/da active
- 1994-03-18 US US08/525,771 patent/US5756483A/en not_active Expired - Lifetime
- 1994-03-18 WO PCT/EP1994/000891 patent/WO1994022445A2/en active IP Right Grant
-
1998
- 1998-04-17 US US09/062,633 patent/US5942251A/en not_active Expired - Lifetime
-
2004
- 2004-10-06 JP JP2004293322A patent/JP2005041884A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
PT865789E (pt) | 2005-05-31 |
EP0865789B1 (en) | 2005-03-16 |
WO1994022445A3 (en) | 1995-01-05 |
DE69432789D1 (de) | 2003-07-10 |
PT689438E (pt) | 2003-10-31 |
US5942251A (en) | 1999-08-24 |
DE69434304T2 (de) | 2005-12-29 |
EP0689438A1 (en) | 1996-01-03 |
ATE241984T1 (de) | 2003-06-15 |
ATE290864T1 (de) | 2005-04-15 |
AU6428894A (en) | 1994-10-24 |
WO1994022445A2 (en) | 1994-10-13 |
DE69432789T2 (de) | 2003-12-04 |
DK0865789T3 (da) | 2005-07-18 |
EP0689438B1 (en) | 2003-06-04 |
EP0865789A3 (en) | 1999-01-07 |
ES2239369T3 (es) | 2005-09-16 |
DE69434304D1 (de) | 2005-04-21 |
DK0689438T3 (da) | 2003-09-29 |
US5756483A (en) | 1998-05-26 |
JPH08508472A (ja) | 1996-09-10 |
EP0865789A2 (en) | 1998-09-23 |
JP2005041884A (ja) | 2005-02-17 |
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