BR9606674B1 - novo derivado de composto de antraciclina e preparação farmacêutica contendo o mesmo. - Google Patents
novo derivado de composto de antraciclina e preparação farmacêutica contendo o mesmo.Info
- Publication number
- BR9606674B1 BR9606674B1 BRPI9606674-1A BR9606674A BR9606674B1 BR 9606674 B1 BR9606674 B1 BR 9606674B1 BR 9606674 A BR9606674 A BR 9606674A BR 9606674 B1 BR9606674 B1 BR 9606674B1
- Authority
- BR
- Brazil
- Prior art keywords
- same
- pharmaceutical preparation
- preparation containing
- new derivative
- anthracycline compound
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP25340495 | 1995-09-29 | ||
PCT/JP1996/002789 WO1997012895A1 (fr) | 1995-09-29 | 1996-09-26 | Nouveaux derives de composes d'anthracycline, et preparations medicamenteuses les contenant |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9606674A BR9606674A (pt) | 1997-10-21 |
BR9606674B1 true BR9606674B1 (pt) | 2010-08-10 |
Family
ID=17250915
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9606674-1A BR9606674B1 (pt) | 1995-09-29 | 1996-09-26 | novo derivado de composto de antraciclina e preparação farmacêutica contendo o mesmo. |
Country Status (9)
Country | Link |
---|---|
US (1) | US6080396A (pt) |
EP (1) | EP0795561B1 (pt) |
JP (1) | JP4039466B2 (pt) |
KR (1) | KR100413029B1 (pt) |
CN (2) | CN1069099C (pt) |
BR (1) | BR9606674B1 (pt) |
DE (1) | DE69625326T2 (pt) |
ES (1) | ES2185801T3 (pt) |
WO (1) | WO1997012895A1 (pt) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2000506899A (ja) * | 1996-03-22 | 2000-06-06 | プリーベ,ウォールドマー | ドキソルビシン耐性腫瘍に対する高活性を有するビス―アントラサイクリン |
KR100566336B1 (ko) * | 1998-06-04 | 2006-03-31 | 가오가부시끼가이샤 | 폴리머 에멀젼 및 그 제조법 |
KR100701904B1 (ko) | 1999-08-21 | 2007-04-02 | 알타나 파마 아게 | Pde 억제제 및 베타 2 아드레날린수용체 작동제의상승적 조합 |
US6338859B1 (en) * | 2000-06-29 | 2002-01-15 | Labopharm Inc. | Polymeric micelle compositions |
US6939564B2 (en) | 2001-06-08 | 2005-09-06 | Labopharm, Inc. | Water-soluble stabilized self-assembled polyelectrolytes |
US7138490B2 (en) * | 2001-06-20 | 2006-11-21 | Nippon Kayaku Kabushiki Kaisha | Block copolymer reduced in impurity content, polymeric carrier, pharmaceutical preparations in polymeric form and process for the preparation of the same |
JP4063510B2 (ja) * | 2001-07-13 | 2008-03-19 | ナノキャリア株式会社 | 薬物含有高分子ミセルの凍結乾燥用組成物およびその凍結乾燥製剤 |
JP2004018494A (ja) * | 2002-06-19 | 2004-01-22 | Japan Science & Technology Corp | ブロック共重合体−薬剤複合体の製造法 |
US20050004038A1 (en) * | 2003-06-27 | 2005-01-06 | Lyon Robert P. | Bivalent inhibitors of Glutathione-S-Transferases |
US7311901B2 (en) * | 2003-10-10 | 2007-12-25 | Samyang Corporation | Amphiphilic block copolymer and polymeric composition comprising the same for drug delivery |
US20050226932A1 (en) * | 2004-04-09 | 2005-10-13 | Samyang Corporation | Pharmaceutical formulations for itraconazole |
JP4758346B2 (ja) * | 2004-07-05 | 2011-08-24 | 財団法人神奈川科学技術アカデミー | 高分子ミセル型mri造影剤 |
CA2666697C (en) * | 2006-10-19 | 2015-03-31 | Nanocarrier Co., Ltd. | Block copolymer for drug conjugates and pharmaceutical composition |
WO2009050203A1 (en) * | 2007-10-15 | 2009-04-23 | Revolymer Limited | Solvent-free synthesis of amphiphilic polymeric material |
CA2756072A1 (en) * | 2009-03-30 | 2010-10-14 | Cerulean Pharma Inc. | Polymer-agent conjugates, particles, compositions, and related methods of use |
WO2010114770A1 (en) * | 2009-03-30 | 2010-10-07 | Cerulean Pharma Inc. | Polymer-agent conjugates, particles, compositions, and related methods of use |
WO2010114768A1 (en) * | 2009-03-30 | 2010-10-07 | Cerulean Pharma Inc. | Polymer-epothilone conjugates, particles, compositions, and related methods of use |
WO2010127154A1 (en) * | 2009-04-30 | 2010-11-04 | Intezyne Technologies, Incorporated | Polymers for polynucleotide encapsulation |
EP2424359A4 (en) | 2009-04-30 | 2014-01-15 | Intezyne Technologies Inc | POLYMIC MICELLES WITH ANTHRACYCLINES FOR THE TREATMENT OF CANCER |
US8524784B2 (en) | 2009-04-30 | 2013-09-03 | Intezyne Technologies, Incorporated | Polymer micelles containing anthracylines for the treatment of cancer |
WO2013124867A1 (en) | 2012-02-21 | 2013-08-29 | Amrita Vishwa Vidyapeetham University | Polymer - polymer or polymer - protein core - shell nano medicine loaded with multiple drug molecules |
WO2014141289A1 (en) | 2013-03-12 | 2014-09-18 | Amrita Vishwa Vidyapeetham University | Photo - chemo composition on the basis of microcapsules with a core -shell structure |
CN106947107B (zh) * | 2017-03-24 | 2019-08-09 | 西北工业大学 | 孔壁上接枝有阿霉素的超支化聚苯乙烯多孔膜的制备方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4263428A (en) * | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
FR2522269A1 (fr) * | 1982-02-26 | 1983-09-02 | Pasteur Institut | Agents antitumoraux, tels que la daunorubicine, a efficacite amelioree, leur obtention et procede pour augmenter l'efficacite des agents antitumoraux |
JP2517760B2 (ja) * | 1989-05-11 | 1996-07-24 | 新技術事業団 | 水溶性高分子化医薬製剤 |
US4965348A (en) * | 1989-05-19 | 1990-10-23 | Bristol-Myers Company | Dimeric epipodophyllotoxin glucoside derivatives |
JP2626654B2 (ja) * | 1990-03-31 | 1997-07-02 | 科学技術振興事業団 | 標的指向性高分子医薬化合物及びその中間体 |
JP3310000B2 (ja) * | 1990-11-07 | 2002-07-29 | 靖久 桜井 | 水溶性高分子抗癌剤及び薬物担持用担体 |
JP3111099B2 (ja) * | 1991-10-31 | 2000-11-20 | 科学技術振興事業団 | 水溶性高分子化薬剤の製造法 |
JPH05117385A (ja) * | 1991-10-31 | 1993-05-14 | Res Dev Corp Of Japan | ブロツク共重合体の製造法、ブロツク共重合体及び水溶性高分子抗癌剤 |
KR940003548U (ko) * | 1992-08-14 | 1994-02-21 | 김형술 | 세탁물 건조기 |
JP3270592B2 (ja) * | 1992-10-26 | 2002-04-02 | 日本化薬株式会社 | ブロック共重合体−抗癌剤複合体医薬製剤 |
JPH06206830A (ja) * | 1992-10-27 | 1994-07-26 | Nippon Kayaku Co Ltd | ブロック共重合体−薬剤複合体及び高分子ブロック共重合体 |
JP3682475B2 (ja) * | 1993-08-31 | 2005-08-10 | 靖久 桜井 | 水溶性抗癌剤 |
JP2690276B2 (ja) * | 1995-01-10 | 1997-12-10 | 科学技術振興事業団 | 静電結合型高分子ミセル薬物担体とその薬剤 |
-
1996
- 1996-09-26 JP JP51067097A patent/JP4039466B2/ja not_active Expired - Lifetime
- 1996-09-26 DE DE69625326T patent/DE69625326T2/de not_active Expired - Lifetime
- 1996-09-26 EP EP96932005A patent/EP0795561B1/en not_active Expired - Lifetime
- 1996-09-26 WO PCT/JP1996/002789 patent/WO1997012895A1/ja active IP Right Grant
- 1996-09-26 KR KR1019970703611A patent/KR100413029B1/ko not_active IP Right Cessation
- 1996-09-26 BR BRPI9606674-1A patent/BR9606674B1/pt not_active IP Right Cessation
- 1996-09-26 ES ES96932005T patent/ES2185801T3/es not_active Expired - Lifetime
- 1996-09-26 CN CN96191130A patent/CN1069099C/zh not_active Expired - Fee Related
- 1996-09-26 US US08/836,965 patent/US6080396A/en not_active Expired - Fee Related
-
2000
- 2000-07-11 CN CNB001219014A patent/CN1155392C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0795561B1 (en) | 2002-12-11 |
US6080396A (en) | 2000-06-27 |
BR9606674A (pt) | 1997-10-21 |
CN1069099C (zh) | 2001-08-01 |
KR100413029B1 (ko) | 2004-04-30 |
JP4039466B2 (ja) | 2008-01-30 |
DE69625326D1 (de) | 2003-01-23 |
KR987000322A (ko) | 1998-03-30 |
ES2185801T3 (es) | 2003-05-01 |
WO1997012895A1 (fr) | 1997-04-10 |
CN1288728A (zh) | 2001-03-28 |
DE69625326T2 (de) | 2003-09-18 |
CN1155392C (zh) | 2004-06-30 |
CN1165518A (zh) | 1997-11-19 |
EP0795561A1 (en) | 1997-09-17 |
EP0795561A4 (en) | 1998-11-11 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B25A | Requested transfer of rights approved |
Owner name: NIPPON KAYAKU KABUSHIKI KAISHA (JP) , YASUHISA SAK Free format text: TRANSFERIDO DE: JAPAN SCIENCE AND TECHNOLOGY CORPORATION |
|
B25A | Requested transfer of rights approved |
Owner name: NIPPON KAYAKU KABUSHIKI KAISHA (JP) , YASUHISA SAK Free format text: TRANSFERIDO DE: JAPAN SCIENCE AND TECHNOLOGY AGENCY |
|
B09S | Decision of refusal: publication cancelled [chapter 9.2.2 patent gazette] |
Free format text: ANULADA A PUBLICACAO DE INDEFERIMENTO POR TER SIDO INDEVIDA. |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B09A | Decision: intention to grant [chapter 9.1 patent gazette] | ||
B16A | Patent or certificate of addition of invention granted [chapter 16.1 patent gazette] |
Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 10/08/2010, OBSERVADAS AS CONDICOES LEGAIS. |
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B22O | Other matters related to patents and certificates of addition of invention: legal action concerning patent |
Free format text: INPI-52400.062008/2013 ORIGEM: JUIZO DA 013A VARA FEDERAL DO RIO DE JANEIRO PROCESSO NO 0132270-62.2013.4.02.5101 ACAO DE NULIDADE DAS PATENTES SUBMETIDAS AO MAILBOX (ART. 229, PARAGRAFO UNICO DA LPI); ALTERNATIVAMENTE, A DECRETACAO DA NULIDADE PARCIAL PARA CORRECAO DO PRAZO DE VIGENCIA; SUBSIDIARIAMENTE, CASO SE ENTENDA NAO SER O CASO DE NULIDADE, A CORRECAO DO ATO ADMINISTRATIVO PARA ADEQUACAO DA VIGENCIA DAS PATENTES. AUTOR: INSTITUTO NACIONAL DA PROPRIEDADE INDUSTRIAL - INPI REU:NIPPON KAYAKU KABUSHIKI KAISHA, NOVARTIS AG, NOVARTIS SA, NOVARTISINS, NOVARTIS CONSUMER HEALTH S.A. |
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B24H | Lapse because of non-payment of annual fees (definitively: art 78 iv lpi) |
Free format text: EXTINCAO DEFINITIVA - ART. 78 INCISO IV DA LPI |
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B24F | Patent annual fee: publication cancelled |
Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2234 DE 29/10/2013 POR TER SIDO INDEVIDA. |
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B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE A 16O, 17O, 18O, 19O E 20O RETRIBUICAO ANUAL. |