DE2702600A1 - Neue aminoalkoxyphenyl-derivate - Google Patents
Neue aminoalkoxyphenyl-derivateInfo
- Publication number
- DE2702600A1 DE2702600A1 DE19772702600 DE2702600A DE2702600A1 DE 2702600 A1 DE2702600 A1 DE 2702600A1 DE 19772702600 DE19772702600 DE 19772702600 DE 2702600 A DE2702600 A DE 2702600A DE 2702600 A1 DE2702600 A1 DE 2702600A1
- Authority
- DE
- Germany
- Prior art keywords
- group
- methyl
- hydrogen atom
- phenyl
- carbon atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Priority Applications (37)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19772702600 DE2702600A1 (de) | 1977-01-22 | 1977-01-22 | Neue aminoalkoxyphenyl-derivate |
FI773717A FI63393C (fi) | 1977-01-22 | 1977-12-09 | Foerfarande foer framstaellning av farmakologiskt vaerdefulla isokinolin-1(2h)-oner eller 1,6-naftyridin-5(6h)oner |
BG038210A BG28573A3 (bg) | 1977-01-22 | 1977-12-26 | Метод за получаване на аминоалкоксифенилови производни |
ES465455A ES465455A1 (es) | 1977-01-22 | 1977-12-27 | Procedimiento para la preparacion de nuevos derivados amino-alcoxifenilicos. |
US05/867,308 US4154837A (en) | 1977-01-22 | 1978-01-06 | (Aminoalkoxy-aryl)-substituted isoquinolinones and naphthydrinones and salts thereof, and hypotensive compositions and methods employing them |
AT11078A AT361480B (de) | 1977-01-22 | 1978-01-09 | Verfahren zur herstellung von neuen amino- alkoxyphenyl-derivaten und deren physiologisch vertraeglichen saeureadditionssalzen |
RO7892901A RO72911A (ro) | 1977-01-22 | 1978-01-13 | Procedeu pentru prepararea unor izochinolin-1(2h)-one si 1,6-naftiridin-5(6h)-one |
SU782566499A SU677654A3 (ru) | 1977-01-22 | 1978-01-17 | Способ получени производных аминоалкоксифенила или их солей |
CH52378A CH640227A5 (de) | 1977-01-22 | 1978-01-18 | Aminoalkoxyphenyl-derivate. |
DD78203307A DD135283A5 (de) | 1977-01-22 | 1978-01-19 | Verfahren zur herstellung von neuen aminoalkoxyphenyl-derivaten |
CS78380A CS195653B2 (en) | 1977-01-22 | 1978-01-19 | Method of producing new aminoalkoxyphenylderivatives |
YU134/78A YU40504B (en) | 1977-01-22 | 1978-01-19 | Process for preparing new aminoalkoxyphenenyl derivatives |
BE184522A BE863160A (fr) | 1977-01-22 | 1978-01-20 | Nouveaux derives aminoalcoxyphenyles, leur preparation et leur utilisation en tant que medicaments |
IE139/78A IE46376B1 (en) | 1977-01-22 | 1978-01-20 | Isoquinoline and naphthyridine substituted aminoalkoxyphenyl derivatives |
AU32581/78A AU516692B2 (en) | 1977-01-02 | 1978-01-20 | Isoquinoline and 1,6-naphtyridine derivitives |
NL7800717A NL7800717A (nl) | 1977-01-22 | 1978-01-20 | Nieuwe aminoalkoxyfenyl-derivaten. |
NO780214A NO149502C (no) | 1977-01-22 | 1978-01-20 | Analogifremgangsmaate for fremstilling av fysiologisk aktive aminoalkoksyfenylderivater |
HU78TO1068A HU176895B (en) | 1977-01-22 | 1978-01-20 | Process for preparing new aminoalkoxy-phenyl-derivatives |
NZ186287A NZ186287A (en) | 1977-01-22 | 1978-01-20 | 3-(3'-substituted-diaminopropoxy(phenyl or phenalkyl)-iso-quinolin-1(2h)-ones or napthyridin-1(2h)-ones |
DK30578A DK149847C (da) | 1977-01-22 | 1978-01-20 | Analogifremgangsmaade til fremstilling af aminoalkoxyphenyl-derivater af isoquinolinoner eller napthyridinoner |
LU78919A LU78919A1 (de) | 1977-01-22 | 1978-01-20 | Verfahren zur herstellung von neuen aminoalkoxyphenyl-derivaten |
CA295,361A CA1106846A (en) | 1977-01-22 | 1978-01-20 | Aminoalkoxyphenyl-derivatives |
PH20691A PH13911A (en) | 1977-01-22 | 1978-01-20 | Neue aminoalkoxyphenyl-derivate |
PT67561A PT67561B (de) | 1977-01-22 | 1978-01-20 | Neue aminoalkoxyphenyl-derivate |
GR55214A GR64093B (en) | 1977-01-22 | 1978-01-20 | Method for the preparation of new aminoalkoxyphenyl-derivatives |
SE7800739A SE444433B (sv) | 1977-01-22 | 1978-01-20 | Forfarande for framstellning av nya aminoalkoxifenylderivat |
ZA00780365A ZA78365B (en) | 1977-01-22 | 1978-01-20 | Improvements relating to aminoalkoxyphenyl derivates |
IL53857A IL53857A (en) | 1977-01-22 | 1978-01-20 | 3-aminopropoxyphenyl (alkyl) isoquinolin-1(2h)-one (or 1,6-naphthyridine-5(6h)-one) derivatives, their preparation and pharmaceutical compositions containing them |
FR7801684A FR2378014A1 (fr) | 1977-01-22 | 1978-01-20 | Nouveaux derives aminoalcoxyphenyles, leur preparation et leur utilisation en tant que medicaments |
IT47729/78A IT1102816B (it) | 1977-01-22 | 1978-01-20 | Derivati amminoalcossifinilici e procedimento per la loro preparazione |
JP514978A JPS5392786A (en) | 1977-01-22 | 1978-01-20 | Novel aminoalkoxyphenyl derivative |
PL1978204134A PL112130B1 (en) | 1977-01-22 | 1978-01-21 | Method of manufacturing of novel aminoalkoxyphenyl derivatives |
GB2643/78A GB1568021A (en) | 1977-01-22 | 1978-01-23 | Isoquinoline and naphthyridine substituted aminoalkoxphenol derivatives |
AT614979A AT361485B (de) | 1977-01-22 | 1979-09-19 | Verfahren zur herstellung von neuen amino- alkoxyphenyl-derivaten und deren physiologisch vertraeglichen saeureadditionssalzen |
SG42883A SG42883G (en) | 1977-01-22 | 1983-07-19 | Isoquinoline and naphthyridine substituted aminoalkoxyphenyl derivatives |
HK600/83A HK60083A (en) | 1977-01-22 | 1983-11-24 | Isoquinoline and naphthyridine substituted aminoalkoxyphenyl derivatives |
MY275/84A MY8400275A (en) | 1977-01-22 | 1984-12-30 | Isoquinoline and naphthyridine substituted aminoalkoxy-phenyl derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19772702600 DE2702600A1 (de) | 1977-01-22 | 1977-01-22 | Neue aminoalkoxyphenyl-derivate |
Publications (1)
Publication Number | Publication Date |
---|---|
DE2702600A1 true DE2702600A1 (de) | 1978-07-27 |
Family
ID=5999300
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19772702600 Ceased DE2702600A1 (de) | 1977-01-02 | 1977-01-22 | Neue aminoalkoxyphenyl-derivate |
Country Status (36)
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0113910A1 (en) * | 1982-12-24 | 1984-07-25 | Nisshin Flour Milling Co., Ltd. | Isocarbostyril derivatives, processes for their preparation and pharmaceutical compositions containing them |
DE3423003A1 (de) * | 1984-06-22 | 1986-01-02 | Beiersdorf Ag, 2000 Hamburg | Benzo(c)(1,8)naphthyridine, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen |
DE3526693A1 (de) * | 1984-07-26 | 1986-02-06 | Mitsui Toatsu Chemicals, Inc., Tokio/Tokyo | Isochinolin-derivat |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4329349A (en) * | 1979-07-25 | 1982-05-11 | Sandoz, Inc. | 6-C1-4 Alkyl-7-phenyl or substituted phenyl-1,6-naphthyridine-5(6H)-ones |
DE3027619A1 (de) * | 1979-07-25 | 1981-02-19 | Sandoz Ag | 6-alkyl-7-phenyl-1,6-naphtyradin- 5(6h)-on-derivate |
US4698341A (en) * | 1983-07-30 | 1987-10-06 | Godecke Aktiengesellschaft | Use of 1,6-naphthyridinone derivatives in treating pulmonary thrombosis |
DE3502831A1 (de) * | 1985-01-29 | 1986-07-31 | Gödecke AG, 1000 Berlin | 1,6-naphthyridinon-derivate, verfahren zu deren herstellung und deren verwendung |
AU2630095A (en) * | 1994-08-04 | 1996-03-04 | C & C Research Laboratories | Novel amine derivative, process for producing the same, and use thereof as antiarrhythmic |
DE19943635A1 (de) * | 1999-09-13 | 2001-03-15 | Bayer Ag | Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften |
JPWO2005115993A1 (ja) * | 2004-05-31 | 2008-03-27 | 萬有製薬株式会社 | キナゾリン誘導体 |
DK2303846T3 (en) * | 2008-06-24 | 2015-08-03 | Sanofi Sa | SUBSTITUTED isoquinolines AND ISOQUINOLINONER AS RHO kinase inhibitors |
RU2532481C2 (ru) * | 2008-06-24 | 2014-11-10 | Санофи-Авентис | Би- и полициклические замещенные производные изохинолина и изохинолинона, полезные в качестве ингибиторов rho-киназы |
MX2010013974A (es) * | 2008-06-24 | 2011-01-14 | Sanofi Aventis | Isoquinolinas e isoquinolinonas 6-sustituidas. |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1394700A (en) * | 1972-11-25 | 1975-05-21 | Aspro Nicholas Ltd | Pharmacologically active isoquinoline derivatives |
GB1446791A (en) * | 1973-09-08 | 1976-08-18 | Thomae Gmbh Dr K | 1,3-diketo-1,2,3,4-tetrahydroisoquinolines |
DE2615406A1 (de) * | 1975-04-09 | 1976-10-14 | Abbott Lab | Beta-adrenergische rezeptoren-blocker |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2538341A (en) * | 1949-09-20 | 1951-01-16 | Smith Kline French Lab | Method for producing 1-hydroxyisoquinolines |
US3432027A (en) * | 1966-01-05 | 1969-03-11 | Lily Tulip Cup Corp | Dispensing container assembly |
US3993656A (en) * | 1974-11-19 | 1976-11-23 | Merck & Co., Inc. | 1,8-Naphthyridine compounds |
DE2611148A1 (de) * | 1975-03-26 | 1976-10-14 | Sandoz Ag | Organische verbindungen, ihre verwendung und herstellung |
-
1977
- 1977-01-22 DE DE19772702600 patent/DE2702600A1/de not_active Ceased
- 1977-12-09 FI FI773717A patent/FI63393C/fi not_active IP Right Cessation
- 1977-12-26 BG BG038210A patent/BG28573A3/xx unknown
- 1977-12-27 ES ES465455A patent/ES465455A1/es not_active Expired
-
1978
- 1978-01-06 US US05/867,308 patent/US4154837A/en not_active Expired - Lifetime
- 1978-01-09 AT AT11078A patent/AT361480B/de not_active IP Right Cessation
- 1978-01-13 RO RO7892901A patent/RO72911A/ro unknown
- 1978-01-17 SU SU782566499A patent/SU677654A3/ru active
- 1978-01-18 CH CH52378A patent/CH640227A5/de not_active IP Right Cessation
- 1978-01-19 DD DD78203307A patent/DD135283A5/xx unknown
- 1978-01-19 CS CS78380A patent/CS195653B2/cs unknown
- 1978-01-19 YU YU134/78A patent/YU40504B/xx unknown
- 1978-01-20 IL IL53857A patent/IL53857A/xx unknown
- 1978-01-20 FR FR7801684A patent/FR2378014A1/fr active Granted
- 1978-01-20 JP JP514978A patent/JPS5392786A/ja active Pending
- 1978-01-20 NO NO780214A patent/NO149502C/no unknown
- 1978-01-20 GR GR55214A patent/GR64093B/el unknown
- 1978-01-20 HU HU78TO1068A patent/HU176895B/hu unknown
- 1978-01-20 NL NL7800717A patent/NL7800717A/xx not_active Application Discontinuation
- 1978-01-20 ZA ZA00780365A patent/ZA78365B/xx unknown
- 1978-01-20 PT PT67561A patent/PT67561B/pt unknown
- 1978-01-20 IT IT47729/78A patent/IT1102816B/it active
- 1978-01-20 AU AU32581/78A patent/AU516692B2/en not_active Expired
- 1978-01-20 SE SE7800739A patent/SE444433B/sv not_active IP Right Cessation
- 1978-01-20 LU LU78919A patent/LU78919A1/de unknown
- 1978-01-20 IE IE139/78A patent/IE46376B1/en unknown
- 1978-01-20 CA CA295,361A patent/CA1106846A/en not_active Expired
- 1978-01-20 PH PH20691A patent/PH13911A/en unknown
- 1978-01-20 DK DK30578A patent/DK149847C/da not_active IP Right Cessation
- 1978-01-20 BE BE184522A patent/BE863160A/xx not_active IP Right Cessation
- 1978-01-20 NZ NZ186287A patent/NZ186287A/xx unknown
- 1978-01-21 PL PL1978204134A patent/PL112130B1/pl unknown
- 1978-01-23 GB GB2643/78A patent/GB1568021A/en not_active Expired
-
1983
- 1983-07-19 SG SG42883A patent/SG42883G/en unknown
- 1983-11-24 HK HK600/83A patent/HK60083A/xx unknown
-
1984
- 1984-12-30 MY MY275/84A patent/MY8400275A/xx unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1394700A (en) * | 1972-11-25 | 1975-05-21 | Aspro Nicholas Ltd | Pharmacologically active isoquinoline derivatives |
GB1446791A (en) * | 1973-09-08 | 1976-08-18 | Thomae Gmbh Dr K | 1,3-diketo-1,2,3,4-tetrahydroisoquinolines |
DE2615406A1 (de) * | 1975-04-09 | 1976-10-14 | Abbott Lab | Beta-adrenergische rezeptoren-blocker |
Non-Patent Citations (3)
Title |
---|
Chemical Abstracts, Bd. 80, 1974, 133455 a * |
Chemical Abstracts, Bd. 80, 1974, 82715 a * |
NEGWER: Organisch Chemische Arzneimittel und ihre Synonyma, Bd. 1, 1971, S.468 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0113910A1 (en) * | 1982-12-24 | 1984-07-25 | Nisshin Flour Milling Co., Ltd. | Isocarbostyril derivatives, processes for their preparation and pharmaceutical compositions containing them |
DE3423003A1 (de) * | 1984-06-22 | 1986-01-02 | Beiersdorf Ag, 2000 Hamburg | Benzo(c)(1,8)naphthyridine, verfahren zu ihrer herstellung und ihre verwendung sowie diese verbindungen enthaltende zubereitungen |
DE3526693A1 (de) * | 1984-07-26 | 1986-02-06 | Mitsui Toatsu Chemicals, Inc., Tokio/Tokyo | Isochinolin-derivat |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
8131 | Rejection |