DE2524619A1 - (dl)-13-substituierte sulfinyl- prostaglandinartige verbindungen und verfahren zu ihrer herstellung - Google Patents

(dl)-13-substituierte sulfinyl- prostaglandinartige verbindungen und verfahren zu ihrer herstellung

Info

Publication number
DE2524619A1
DE2524619A1 DE19752524619 DE2524619A DE2524619A1 DE 2524619 A1 DE2524619 A1 DE 2524619A1 DE 19752524619 DE19752524619 DE 19752524619 DE 2524619 A DE2524619 A DE 2524619A DE 2524619 A1 DE2524619 A1 DE 2524619A1
Authority
DE
Germany
Prior art keywords
octenyl
carbon atoms
compounds
trans
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19752524619
Other languages
German (de)
English (en)
Inventor
Gilbert J Stork
Karl G Untch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex USA LLC
Original Assignee
Syntex USA LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex USA LLC filed Critical Syntex USA LLC
Publication of DE2524619A1 publication Critical patent/DE2524619A1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P31/00—Preparation of compounds containing a five-membered ring having two side-chains in ortho position to each other, and having at least one oxygen atom directly bound to the ring in ortho position to one of the side-chains, one side-chain containing, not directly bound to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having at least one oxygen atom bound in gamma-position to the ring, e.g. prostaglandins

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19752524619 1974-06-05 1975-06-03 (dl)-13-substituierte sulfinyl- prostaglandinartige verbindungen und verfahren zu ihrer herstellung Pending DE2524619A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/476,362 US3970685A (en) 1974-06-05 1974-06-05 (DL)-13-Substituted sulfinyl-prostaglandin-like compounds

Publications (1)

Publication Number Publication Date
DE2524619A1 true DE2524619A1 (de) 1976-01-02

Family

ID=23891540

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752524619 Pending DE2524619A1 (de) 1974-06-05 1975-06-03 (dl)-13-substituierte sulfinyl- prostaglandinartige verbindungen und verfahren zu ihrer herstellung

Country Status (16)

Country Link
US (1) US3970685A (enExample)
JP (1) JPS5111743A (enExample)
AT (1) AT348156B (enExample)
BE (1) BE829820A (enExample)
CA (1) CA1039277A (enExample)
CH (2) CH611880A5 (enExample)
DE (1) DE2524619A1 (enExample)
DK (1) DK245075A (enExample)
ES (2) ES438237A1 (enExample)
FR (1) FR2273519A1 (enExample)
GB (1) GB1496845A (enExample)
IL (1) IL47354A (enExample)
NL (1) NL7506666A (enExample)
NO (1) NO751975L (enExample)
SE (1) SE7506388L (enExample)
ZA (1) ZA753247B (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2704774A1 (de) * 1976-02-09 1977-08-11 Miles Lab 1-dicarboxy-1-hydroxymethyl-pge tief 1 enthaltendes arzneimittel
DE2708220A1 (de) * 1976-02-25 1977-09-01 Sagami Chem Res Prostaglandin-vorlaeufer und verfahren zu ihrer herstellung

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605381A (nl) * 1975-05-26 1976-11-30 Schering Ag Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking.
US4159343A (en) * 1975-05-26 1979-06-26 Schering Aktiengesellschaft Prostane derivatives
US4026909A (en) * 1975-07-14 1977-05-31 The Upjohn Company Cis-13-PGF2.sub.α analogs
US4085125A (en) * 1976-03-22 1978-04-18 Merck & Co., Inc. 9-Thia-, 9-oxothia-, and 9-dioxothia-11,12-seco-prostaglandins and processes
JPS62152008A (ja) * 1985-12-25 1987-07-07 Fanuc Ltd 送り速度制御方法

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2704774A1 (de) * 1976-02-09 1977-08-11 Miles Lab 1-dicarboxy-1-hydroxymethyl-pge tief 1 enthaltendes arzneimittel
DE2708220A1 (de) * 1976-02-25 1977-09-01 Sagami Chem Res Prostaglandin-vorlaeufer und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ZA753247B (en) 1977-01-26
CA1039277A (en) 1978-09-26
IL47354A0 (en) 1975-07-28
ATA425375A (de) 1978-06-15
AU8179175A (en) 1976-12-09
FR2273519A1 (fr) 1976-01-02
IL47354A (en) 1979-01-31
SE7506388L (sv) 1975-12-08
NL7506666A (nl) 1975-12-09
CH611880A5 (enExample) 1979-06-29
DK245075A (da) 1975-12-06
AT348156B (de) 1979-02-12
NO751975L (enExample) 1975-12-08
GB1496845A (en) 1978-01-05
US3970685A (en) 1976-07-20
JPS5111743A (en) 1976-01-30
ES454767A1 (es) 1978-01-01
CH617187A5 (enExample) 1980-05-14
BE829820A (fr) 1975-12-03
ES438237A1 (es) 1977-05-16

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Legal Events

Date Code Title Description
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