IL47354A - (dl)-2 -(acetoxymethyl-,carboxyalk-(en)yl- or carbalkoxyalk(en)yl)-3 -(1 -alkyl-,-phenyl- or -p-tolylsulfinyl-trans-2-alkenyl)-1-(hydroxy or oxo)-cyclopentanes and their preparation - Google Patents

(dl)-2 -(acetoxymethyl-,carboxyalk-(en)yl- or carbalkoxyalk(en)yl)-3 -(1 -alkyl-,-phenyl- or -p-tolylsulfinyl-trans-2-alkenyl)-1-(hydroxy or oxo)-cyclopentanes and their preparation

Info

Publication number
IL47354A
IL47354A IL47354A IL4735475A IL47354A IL 47354 A IL47354 A IL 47354A IL 47354 A IL47354 A IL 47354A IL 4735475 A IL4735475 A IL 4735475A IL 47354 A IL47354 A IL 47354A
Authority
IL
Israel
Prior art keywords
carboxyalk
carbalkoxyalk
tolylsulfinyl
cyclopentanes
acetoxymethyl
Prior art date
Application number
IL47354A
Other languages
English (en)
Other versions
IL47354A0 (en
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of IL47354A0 publication Critical patent/IL47354A0/xx
Publication of IL47354A publication Critical patent/IL47354A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P31/00—Preparation of compounds containing a five-membered ring having two side-chains in ortho position to each other, and having at least one oxygen atom directly bound to the ring in ortho position to one of the side-chains, one side-chain containing, not directly bound to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having at least one oxygen atom bound in gamma-position to the ring, e.g. prostaglandins

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL47354A 1974-06-05 1975-05-26 (dl)-2 -(acetoxymethyl-,carboxyalk-(en)yl- or carbalkoxyalk(en)yl)-3 -(1 -alkyl-,-phenyl- or -p-tolylsulfinyl-trans-2-alkenyl)-1-(hydroxy or oxo)-cyclopentanes and their preparation IL47354A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/476,362 US3970685A (en) 1974-06-05 1974-06-05 (DL)-13-Substituted sulfinyl-prostaglandin-like compounds

Publications (2)

Publication Number Publication Date
IL47354A0 IL47354A0 (en) 1975-07-28
IL47354A true IL47354A (en) 1979-01-31

Family

ID=23891540

Family Applications (1)

Application Number Title Priority Date Filing Date
IL47354A IL47354A (en) 1974-06-05 1975-05-26 (dl)-2 -(acetoxymethyl-,carboxyalk-(en)yl- or carbalkoxyalk(en)yl)-3 -(1 -alkyl-,-phenyl- or -p-tolylsulfinyl-trans-2-alkenyl)-1-(hydroxy or oxo)-cyclopentanes and their preparation

Country Status (16)

Country Link
US (1) US3970685A (xx)
JP (1) JPS5111743A (xx)
AT (1) AT348156B (xx)
BE (1) BE829820A (xx)
CA (1) CA1039277A (xx)
CH (2) CH611880A5 (xx)
DE (1) DE2524619A1 (xx)
DK (1) DK245075A (xx)
ES (2) ES438237A1 (xx)
FR (1) FR2273519A1 (xx)
GB (1) GB1496845A (xx)
IL (1) IL47354A (xx)
NL (1) NL7506666A (xx)
NO (1) NO751975L (xx)
SE (1) SE7506388L (xx)
ZA (1) ZA753247B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4159343A (en) * 1975-05-26 1979-06-26 Schering Aktiengesellschaft Prostane derivatives
NL7605381A (nl) * 1975-05-26 1976-11-30 Schering Ag Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking.
US4026909A (en) * 1975-07-14 1977-05-31 The Upjohn Company Cis-13-PGF2.sub.α analogs
US4022912A (en) * 1976-02-09 1977-05-10 Miles Laboratories, Inc. Use of 1-decarboxy-1-hydroxymethyl-PGE1 in therapeutic bronchodilation
GB1541962A (en) * 1976-02-25 1979-03-14 Sagami Chem Res Prostaglandin precursors and processes for preparing the same
US4085125A (en) * 1976-03-22 1978-04-18 Merck & Co., Inc. 9-Thia-, 9-oxothia-, and 9-dioxothia-11,12-seco-prostaglandins and processes
JPS62152008A (ja) * 1985-12-25 1987-07-07 Fanuc Ltd 送り速度制御方法

Also Published As

Publication number Publication date
ATA425375A (de) 1978-06-15
NO751975L (xx) 1975-12-08
CA1039277A (en) 1978-09-26
GB1496845A (en) 1978-01-05
AU8179175A (en) 1976-12-09
AT348156B (de) 1979-02-12
IL47354A0 (en) 1975-07-28
ES454767A1 (es) 1978-01-01
CH617187A5 (xx) 1980-05-14
ES438237A1 (es) 1977-05-16
BE829820A (fr) 1975-12-03
DE2524619A1 (de) 1976-01-02
JPS5111743A (en) 1976-01-30
NL7506666A (nl) 1975-12-09
FR2273519A1 (fr) 1976-01-02
DK245075A (da) 1975-12-06
US3970685A (en) 1976-07-20
ZA753247B (en) 1977-01-26
SE7506388L (sv) 1975-12-08
CH611880A5 (xx) 1979-06-29

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