ZA753247B - (d1)-13-substituted sulfinyl-prostaglandinlike compounds and methods of making - Google Patents

(d1)-13-substituted sulfinyl-prostaglandinlike compounds and methods of making

Info

Publication number
ZA753247B
ZA753247B ZA3247A ZA753247A ZA753247B ZA 753247 B ZA753247 B ZA 753247B ZA 3247 A ZA3247 A ZA 3247A ZA 753247 A ZA753247 A ZA 753247A ZA 753247 B ZA753247 B ZA 753247B
Authority
ZA
South Africa
Prior art keywords
prostaglandinlike
compounds
making
methods
substituted sulfinyl
Prior art date
Application number
ZA3247A
Other languages
English (en)
Inventor
G Stork
K Untch
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of ZA753247B publication Critical patent/ZA753247B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0033—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing sulfur
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P31/00—Preparation of compounds containing a five-membered ring having two side-chains in ortho position to each other, and having at least one oxygen atom directly bound to the ring in ortho position to one of the side-chains, one side-chain containing, not directly bound to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having at least one oxygen atom bound in gamma-position to the ring, e.g. prostaglandins

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA3247A 1974-06-05 1975-05-20 (d1)-13-substituted sulfinyl-prostaglandinlike compounds and methods of making ZA753247B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/476,362 US3970685A (en) 1974-06-05 1974-06-05 (DL)-13-Substituted sulfinyl-prostaglandin-like compounds

Publications (1)

Publication Number Publication Date
ZA753247B true ZA753247B (en) 1977-01-26

Family

ID=23891540

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA3247A ZA753247B (en) 1974-06-05 1975-05-20 (d1)-13-substituted sulfinyl-prostaglandinlike compounds and methods of making

Country Status (16)

Country Link
US (1) US3970685A (xx)
JP (1) JPS5111743A (xx)
AT (1) AT348156B (xx)
BE (1) BE829820A (xx)
CA (1) CA1039277A (xx)
CH (2) CH611880A5 (xx)
DE (1) DE2524619A1 (xx)
DK (1) DK245075A (xx)
ES (2) ES438237A1 (xx)
FR (1) FR2273519A1 (xx)
GB (1) GB1496845A (xx)
IL (1) IL47354A (xx)
NL (1) NL7506666A (xx)
NO (1) NO751975L (xx)
SE (1) SE7506388L (xx)
ZA (1) ZA753247B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7605381A (nl) * 1975-05-26 1976-11-30 Schering Ag Werkwijze voor het bereiden van prostaanderi- vaten en werkwijze voor het bereiden van een geneesmiddel met prostaglandinewerking.
US4159343A (en) * 1975-05-26 1979-06-26 Schering Aktiengesellschaft Prostane derivatives
US4026909A (en) * 1975-07-14 1977-05-31 The Upjohn Company Cis-13-PGF2.sub.α analogs
US4022912A (en) * 1976-02-09 1977-05-10 Miles Laboratories, Inc. Use of 1-decarboxy-1-hydroxymethyl-PGE1 in therapeutic bronchodilation
GB1541962A (en) * 1976-02-25 1979-03-14 Sagami Chem Res Prostaglandin precursors and processes for preparing the same
US4066675A (en) * 1976-03-22 1978-01-03 Merck & Co., Inc. 9-thia- and oxothia- and 9-dioxothia-11,12-seco-prostaglandins and processes
JPS62152008A (ja) * 1985-12-25 1987-07-07 Fanuc Ltd 送り速度制御方法

Also Published As

Publication number Publication date
SE7506388L (sv) 1975-12-08
AU8179175A (en) 1976-12-09
NL7506666A (nl) 1975-12-09
CH611880A5 (xx) 1979-06-29
GB1496845A (en) 1978-01-05
IL47354A (en) 1979-01-31
NO751975L (xx) 1975-12-08
DK245075A (da) 1975-12-06
US3970685A (en) 1976-07-20
ES454767A1 (es) 1978-01-01
AT348156B (de) 1979-02-12
CA1039277A (en) 1978-09-26
DE2524619A1 (de) 1976-01-02
ATA425375A (de) 1978-06-15
CH617187A5 (xx) 1980-05-14
ES438237A1 (es) 1977-05-16
JPS5111743A (en) 1976-01-30
BE829820A (fr) 1975-12-03
IL47354A0 (en) 1975-07-28
FR2273519A1 (fr) 1976-01-02

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