DE2500076C3 - Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen - Google Patents

Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen

Info

Publication number
DE2500076C3
DE2500076C3 DE2500076A DE2500076A DE2500076C3 DE 2500076 C3 DE2500076 C3 DE 2500076C3 DE 2500076 A DE2500076 A DE 2500076A DE 2500076 A DE2500076 A DE 2500076A DE 2500076 C3 DE2500076 C3 DE 2500076C3
Authority
DE
Germany
Prior art keywords
gamma globulin
precipitate
gamma
solution
precipitation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2500076A
Other languages
German (de)
English (en)
Other versions
DE2500076A1 (de
DE2500076B2 (de
Inventor
Waldemar Schneider
Dietrich Wolter
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Armour Pharma GmbH
Original Assignee
Schura Blutderivate & Co Kg 4150 Krefeld De GmbH
Schura Blutderivate & Co Kg 4150 Krefeld GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schura Blutderivate & Co Kg 4150 Krefeld De GmbH, Schura Blutderivate & Co Kg 4150 Krefeld GmbH filed Critical Schura Blutderivate & Co Kg 4150 Krefeld De GmbH
Priority to DE2500076A priority Critical patent/DE2500076C3/de
Priority to NLAANVRAGE7514627,A priority patent/NL179824C/xx
Priority to SE7514388A priority patent/SE437470B/xx
Priority to DK584375A priority patent/DK144679C/da
Priority to AT981675A priority patent/AT344883B/de
Priority to FR7539814A priority patent/FR2296429A1/fr
Priority to JP15974275A priority patent/JPS5512001B2/ja
Priority to DD190614A priority patent/DD121875A5/xx
Priority to GB53020/75A priority patent/GB1495159A/en
Priority to EG775/75A priority patent/EG11987A/xx
Priority to CA242,734A priority patent/CA1058075A/en
Priority to IE2826/75A priority patent/IE43449B1/en
Priority to ZA00758050A priority patent/ZA758050B/xx
Priority to ES443982A priority patent/ES443982A1/es
Priority to IL48766A priority patent/IL48766A/xx
Priority to IN2413/CAL/75A priority patent/IN143525B/en
Priority to BE6045314A priority patent/BE837211A/xx
Priority to AU87921/75A priority patent/AU505416B2/en
Priority to SU7502306354A priority patent/SU576898A3/ru
Priority to PL1976186289A priority patent/PL99599B1/pl
Priority to MX663076U priority patent/MX5052E/es
Publication of DE2500076A1 publication Critical patent/DE2500076A1/de
Publication of DE2500076B2 publication Critical patent/DE2500076B2/de
Application granted granted Critical
Publication of DE2500076C3 publication Critical patent/DE2500076C3/de
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE2500076A 1975-01-02 1975-01-02 Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen Expired DE2500076C3 (de)

Priority Applications (21)

Application Number Priority Date Filing Date Title
DE2500076A DE2500076C3 (de) 1975-01-02 1975-01-02 Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen
NLAANVRAGE7514627,A NL179824C (nl) 1975-01-02 1975-12-16 Werkwijze voor het winnen van intraveneus verdraagbare gammaglobulinen.
SE7514388A SE437470B (sv) 1975-01-02 1975-12-18 Forfarande for utvinning av ett rent gammaglobulinpreparat, som tolereras vid intravenos administrering
DK584375A DK144679C (da) 1975-01-02 1975-12-22 Fremgangsmaade til udvinding af intravenoeskompatible gammaglobuliner
AT981675A AT344883B (de) 1975-01-02 1975-12-23 Verfahren zur gewinnung von intravenoesvertraeglichem gammaglobulin
FR7539814A FR2296429A1 (fr) 1975-01-02 1975-12-26 Procede pour ameliorer la tolerance a l'injection intraveineuse de gammaglobuline
JP15974275A JPS5512001B2 (en) 1975-01-02 1975-12-27 Improving the compatibility of gamma globulins
GB53020/75A GB1495159A (en) 1975-01-02 1975-12-29 Process reducing the anticomplementary activity of gamma globulins
DD190614A DD121875A5 (US08088816-20120103-C00036.png) 1975-01-02 1975-12-29
IE2826/75A IE43449B1 (en) 1975-01-02 1975-12-30 Process reducing the anticomplementary activity of gamma globulins
EG775/75A EG11987A (en) 1975-01-02 1975-12-30 Process of improving the compatibility of gamma globulins
ZA00758050A ZA758050B (en) 1975-01-02 1975-12-30 Process of improving the compatibility of gamma globulins
ES443982A ES443982A1 (es) 1975-01-02 1975-12-30 Un procedimiento para elevar la tolerancia intravenosa de globulinas gamma precipitadas de la sangre o de productos sanguineos.
IL48766A IL48766A (en) 1975-01-02 1975-12-30 Process for obtaining intravenous-compatible gamma globulin
IN2413/CAL/75A IN143525B (US08088816-20120103-C00036.png) 1975-01-02 1975-12-30
BE6045314A BE837211A (fr) 1975-01-02 1975-12-30 Procede pour ameliorer la tolerance a l'injection intraveineuse de gammaglobuline
AU87921/75A AU505416B2 (en) 1975-01-02 1975-12-30 Improving the compatibility of gamma globulins
CA242,734A CA1058075A (en) 1975-01-02 1975-12-30 Process of improving the compatibility of gamma globulins
SU7502306354A SU576898A3 (ru) 1975-01-02 1975-12-31 Способ снижени реактогенности гамма-глобулина
PL1976186289A PL99599B1 (pl) 1975-01-02 1976-01-01 Sposob otrzymywania tolerowanej srodzylnie gammaglobuliny
MX663076U MX5052E (es) 1975-01-02 1976-01-05 Procedimiento para preparar gamma globulinas iv compatibles

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2500076A DE2500076C3 (de) 1975-01-02 1975-01-02 Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen

Publications (3)

Publication Number Publication Date
DE2500076A1 DE2500076A1 (de) 1976-07-08
DE2500076B2 DE2500076B2 (de) 1979-02-22
DE2500076C3 true DE2500076C3 (de) 1982-11-18

Family

ID=5935911

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2500076A Expired DE2500076C3 (de) 1975-01-02 1975-01-02 Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen

Country Status (20)

Country Link
JP (1) JPS5512001B2 (US08088816-20120103-C00036.png)
AT (1) AT344883B (US08088816-20120103-C00036.png)
AU (1) AU505416B2 (US08088816-20120103-C00036.png)
BE (1) BE837211A (US08088816-20120103-C00036.png)
CA (1) CA1058075A (US08088816-20120103-C00036.png)
DD (1) DD121875A5 (US08088816-20120103-C00036.png)
DE (1) DE2500076C3 (US08088816-20120103-C00036.png)
DK (1) DK144679C (US08088816-20120103-C00036.png)
EG (1) EG11987A (US08088816-20120103-C00036.png)
ES (1) ES443982A1 (US08088816-20120103-C00036.png)
FR (1) FR2296429A1 (US08088816-20120103-C00036.png)
GB (1) GB1495159A (US08088816-20120103-C00036.png)
IE (1) IE43449B1 (US08088816-20120103-C00036.png)
IL (1) IL48766A (US08088816-20120103-C00036.png)
IN (1) IN143525B (US08088816-20120103-C00036.png)
NL (1) NL179824C (US08088816-20120103-C00036.png)
PL (1) PL99599B1 (US08088816-20120103-C00036.png)
SE (1) SE437470B (US08088816-20120103-C00036.png)
SU (1) SU576898A3 (US08088816-20120103-C00036.png)
ZA (1) ZA758050B (US08088816-20120103-C00036.png)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2604759C2 (de) * 1976-02-07 1983-06-01 SCHURA Blutderivate GmbH & Co KG, 4150 Krefeld Verfahren zur Gewinnung von iv-verträglichen Γglobulinen
JPS6016406B2 (ja) * 1976-08-06 1985-04-25 マイヤ−、ル−イス、コ−バル 静脈内に投与可能なガンマ・グロブリンの製造法ならびにそれにより調製したガンマ・グロブリン
US4124576A (en) * 1976-12-03 1978-11-07 Coval M L Method of producing intravenously injectable gamma globulin
GB1603244A (en) * 1977-05-20 1981-11-18 Max Planck Gesellschaft Medicaments for the suppression of pathological processes
JPS5822085B2 (ja) * 1977-07-19 1983-05-06 株式会社ミドリ十字 静注用ガンマ・グロブリン製剤
AT359641B (de) * 1978-09-19 1980-11-25 Immuno Ag Verfahren zur herstellung eines intravenoes ver- abreichbaren antikoerperhaeltigen immunglobulin- praeparates
EP0019403B1 (en) * 1979-05-10 1985-07-31 American Hospital Supply Corporation Hydroxyalkyl-starch drug carrier
US4396608A (en) * 1981-08-24 1983-08-02 Cutter Laboratories Intravenously injectable immune serum globulin
DE3271181D1 (en) * 1982-02-08 1986-06-19 Schweiz Serum & Impfinst Intravenously administrable human immunoglobuline and process for its preparation
US4482483A (en) * 1983-04-06 1984-11-13 Armour Pharmceutical Company Composition of intravenous immune globulin
SE8302483L (sv) * 1983-05-02 1984-11-03 Pharmacia Ind Forfarande vid rening av biologiskt aktiva substanser
US5945098A (en) * 1990-02-01 1999-08-31 Baxter International Inc. Stable intravenously-administrable immune globulin preparation
DE19907257A1 (de) * 1999-02-21 2000-09-14 Bernd Horst Meier Mittel zur Steuerung der Diffusion von Injektionslösungen
DE10040707A1 (de) * 2000-08-17 2002-03-14 Braun Melsungen Ag Kolloidale Pharmakomodulation injizierter Arzneimittel
DE10303974A1 (de) 2003-01-31 2004-08-05 Abbott Gmbh & Co. Kg Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
CA2631195C (en) 2005-11-30 2016-04-05 Abbott Laboratories Monoclonal antibodies against amyloid beta protein and uses thereof
CN101432302A (zh) 2005-11-30 2009-05-13 艾博特公司 抗-Aβ球聚体抗体,其抗原结合部分,相应的杂交瘤、核酸、载体、宿主细胞,生产所述抗体的方法,包含所述抗体的组合物,所述抗体的应用以及使用所述抗体的方法
US8455626B2 (en) 2006-11-30 2013-06-04 Abbott Laboratories Aβ conformer selective anti-aβ globulomer monoclonal antibodies
EP2124952A2 (en) 2007-02-27 2009-12-02 Abbott GmbH & Co. KG Method for the treatment of amyloidoses
US8987419B2 (en) 2010-04-15 2015-03-24 AbbVie Deutschland GmbH & Co. KG Amyloid-beta binding proteins
MX358739B (es) 2010-08-14 2018-09-03 Abbvie Inc Star Proteinas de union a amiloide beta.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE348942B (US08088816-20120103-C00036.png) * 1970-06-02 1972-09-18 Statens Bakteriologiska Labor
DE2234069A1 (de) * 1971-07-16 1973-02-08 South African Inventions Verfahren zur herstellung eines gereinigten gamma-globulins
ZA738779B (en) * 1972-11-27 1974-10-30 Baxter Laboratories Inc Production of gamma globulin
JPS49101516A (US08088816-20120103-C00036.png) * 1973-01-13 1974-09-25

Also Published As

Publication number Publication date
ATA981675A (de) 1977-12-15
FR2296429A1 (fr) 1976-07-30
ES443982A1 (es) 1977-07-16
CA1058075A (en) 1979-07-10
JPS5191321A (en) 1976-08-10
SE437470B (sv) 1985-03-04
DK144679B (da) 1982-05-10
ZA758050B (en) 1976-12-29
DK584375A (da) 1976-07-03
DE2500076A1 (de) 1976-07-08
IL48766A (en) 1979-11-30
AU8792175A (en) 1977-07-14
GB1495159A (en) 1977-12-14
IN143525B (US08088816-20120103-C00036.png) 1977-12-17
IL48766A0 (en) 1976-02-29
SE7514388L (sv) 1976-07-05
PL99599B1 (pl) 1978-07-31
DD121875A5 (US08088816-20120103-C00036.png) 1976-09-05
NL179824B (nl) 1986-06-16
DK144679C (da) 1982-10-11
FR2296429B1 (US08088816-20120103-C00036.png) 1978-12-01
NL179824C (nl) 1986-11-17
SU576898A3 (ru) 1977-10-15
AU505416B2 (en) 1979-11-22
NL7514627A (nl) 1976-07-06
IE43449L (en) 1976-07-02
BE837211A (fr) 1976-06-30
DE2500076B2 (de) 1979-02-22
IE43449B1 (en) 1981-02-25
EG11987A (en) 1981-12-31
AT344883B (de) 1978-08-10
JPS5512001B2 (en) 1980-03-29

Similar Documents

Publication Publication Date Title
DE2500076C3 (de) Verfahren zur Gewinnung von intravenös-verträglichen Gammaglobulinen
DE3886134T2 (de) Polysaccharide, extrahiert aus Pflanzen und verwendet als Medizinen und Zusatzstoffe für Nahrungsmittel.
DE2936047C2 (US08088816-20120103-C00036.png)
DE2333883C3 (de) Verfahren zur Herstellung von hochgereinigtem Humanalbumin
DE69012154T2 (de) Heparinderivate und Verfahren zu ihrer Herstellung.
DE2324717C3 (de) Verfahren zur Herstellung eines stabilen AHF-Konzentrates (Faktor VIII)
DE2219635C3 (de) Insulinsalz-Protamin-Komplexe und Verfahren zu ihrer Herstellung
DE3039566A1 (de) Verfahren zur reinigung von interferon
DE3026180C2 (de) Rifamycin-SV-Salze von basischen Aminosäuren, Verfahren zu ihrer Herstellung und Arzneimittel zur intraartikulären Injektion bei der Bekämpfung von rheumatoider Arthritis
DE4435392A1 (de) Hochmolekulare und niedermolekulare Fraktionen des von Willebrand-Faktors
DE2433209A1 (de) Hitzestabile plasmaproteinloesungen, verfahren zu ihrer herstellung und arzneipraeparate
DE2403994A1 (de) Herstellung von antisera
DE2837168A1 (de) Verfahren zur herstellung einer fuer die intravenoese anwendung geeigneten immunglobulinloesung
DE2835843A1 (de) Verfahren zur herstellung einer fuer die intravenoese anwendung geeigneten gammaglobulinloesung
DE2604759C2 (de) Verfahren zur Gewinnung von iv-verträglichen Γglobulinen
DE1940130C2 (de) Verfahren zur Reinigung von Insulin, nach diesem Verfahren gereinigtes Insulin und dessen Verwendung
DE2856939A1 (de) Verfahren zur gewinnung von intravenoes-vertraeglichen gammaglobulinen
CH639394A5 (de) Verfahren zur herstellung von immunglobulinpraeparationen mit verminderter komplementaktivitaet.
DE1076888B (de) Verfahren zur Gewinnung atmungsfoerdernder Wirkstoffe fuer therapeutische Zwecke
DE2415079C3 (de) Verfahren zum Isolieren von Albumin aus Blutplasma
DE1148037B (de) Verfahren zur Herstellung eines desaggregierten, das Komplementsystem nicht beeinflussenden Gammaglobulins
DE3034529C2 (de) Leukorekrutin: Ein Entzündungsmediatorprotein aus Säugerserum zur Induzierung einer Leukozytosereaktion, Herstellungsverfahren, Gewinnung in molekular einheitlicher, kristallisierbarer und biologisch spezifisch wirkender Form und Leukorekrutin enthaltendes Arzneimittel
AT271725B (de) Verfahren zur Gewinnung von Gammaglobulin
DE1767404B2 (de) Verfahren zur Gewinnung von Lysozym aus einem lysozymhaltigen Ausgangsmaterial
DE1000963C2 (de) Verfahren zur Herstellung von biologisch aktiven, Vitamine der B-Gruppe enthaltenden Zubereitungen

Legal Events

Date Code Title Description
OI Miscellaneous see part 1
OI Miscellaneous see part 1
BGA New person/name/address of the applicant
AG Has addition no.

Ref country code: DE

Ref document number: 2604759

Format of ref document f/p: P

C3 Grant after two publication steps (3rd publication)
AG Has addition no.

Ref country code: DE

Ref document number: 2604759

Format of ref document f/p: P

8327 Change in the person/name/address of the patent owner

Owner name: ARMOUR PHARMA GMBH & CO KG, 3440 ESCHWEGE, DE

8327 Change in the person/name/address of the patent owner

Owner name: ARMOUR PHARMA GMBH & CO. KG, 4800 BIELEFELD, DE

8327 Change in the person/name/address of the patent owner

Owner name: ARMOUR PHARMA GMBH, 3440 ESCHWEGE, DE

8339 Ceased/non-payment of the annual fee